Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Ashley J. Lamparello"'
Autor:
Tianmeng Chen, Matthew J. Delano, Kong Chen, Jason L. Sperry, Rami A. Namas, Ashley J. Lamparello, Meihong Deng, Julia Conroy, Lyle L. Moldawer, Philip A. Efron, Patricia Loughran, Christopher Seymour, Derek C. Angus, Yoram Vodovotz, Wei Chen, Timothy R. Billiar
Publikováno v:
JCI Insight, Vol 6, Iss 2 (2021)
Immune dysfunction is an important factor driving mortality and adverse outcomes after trauma but remains poorly understood, especially at the cellular level. To deconvolute the trauma-induced immune response, we applied single-cell RNA sequencing to
Externí odkaz:
https://doaj.org/article/aa87caa1bd944fb59beac3cbabf37d4a
Autor:
Timothy R. Billiar, Rami A. Namas, Fayten El-Dehaibi, Maria Cohen, Yoram Vodovotz, Yan Xu, Ashley J. Lamparello, A. Kaynar, Lukas Schimunek
Publikováno v:
Shock
Acute illness is a complex constellation of responses involving dysregulated inflammatory and immune responses, which are ultimately associated with multiple organ dysfunction. Gene association studies have associated single-nucleotide polymorphisms
Autor:
Ashley J. Lamparello, Greg Constantine, Rajaie Namas, Timothy R. Billiar, Eric A. Elster, Yoram Vodovotz, Todd O. McKinley
Publikováno v:
Journal of Internal Medicine. 286:2-15
Progress in the testing of therapies targeting the immune response following trauma, a leading cause of morbidity and mortality worldwide, has been slow. We propose that the design of interventional trials in trauma would benefit from a scheme or pla
Autor:
Christopher W. Seymour, Tianmeng Chen, Rami A. Namas, Kong Chen, Jason L. Sperry, Derek C. Angus, Matthew J. Delano, Wei Chen, Yoram Vodovotz, Timothy R. Billiar, Ashley J. Lamparello, Patricia Loughran, Lyle L. Moldawer, Julia Conroy, Meihong Deng, Philip A. Efron
Publikováno v:
JCI Insight
JCI Insight, Vol 6, Iss 2 (2021)
JCI Insight, Vol 6, Iss 2 (2021)
Immune dysfunction is an important factor driving mortality and adverse outcomes after trauma but remains poorly understood, especially at the cellular level. To deconvolute the trauma-induced immune response, we applied single-cell RNA sequencing to
Autor:
Ruben Zamora, Timothy R. Billiar, Yoram Vodovotz, Fayten El-Dehaibi, Rami A. Namas, Ashley J. Lamparello, Derek Barclay, Lukas Schimunek, Jinling Yin, Maria Cohen
Publikováno v:
Shock
The contribution of individual genetic determinants of aging to the adverse clinical outcomes and altered inflammation mediator networks characteristic of aged trauma patients is unknown. The AA genotype of the aging-related single-nucleotide polymor
Publikováno v:
Journal of the American College of Surgeons. 229:S310
Publikováno v:
J Am Coll Surg
Background Aging is accompanied by alterations in immune functions. How these changes translate into levels of circulating inflammatory mediators and network expression after severe trauma is not well characterized. To address this, we compared time-
Publikováno v:
Journal of the American College of Surgeons. 227:S261