Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Ashley I Beyer"'
Autor:
Shingo Suzuki, R Geoffrey Sargent, Beate Illek, Horst Fischer, Alaleh Esmaeili-Shandiz, Michael J Yezzi, Albert Lee, Yanu Yang, Soya Kim, Peter Renz, Zhongxia Qi, Jingwei Yu, Marcus O Muench, Ashley I Beyer, Alessander O Guimarães, Lin Ye, Judy Chang, Eli J Fine, Thomas J Cradick, Gang Bao, Meghdad Rahdar, Matthew H Porteus, Tsuyoshi Shuto, Hirofumi Kai, Yuet W Kan, Dieter C Gruenert
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 5, Iss C (2016)
Cystic fibrosis (CF) is a recessive inherited disease associated with multiorgan damage that compromises epithelial and inflammatory cell function. Induced pluripotent stem cells (iPSCs) have significantly advanced the potential of developing a perso
Externí odkaz:
https://doaj.org/article/aa7f6c58c90142c2a88dd3a6fd6f2d5f
Autor:
Marcus O Muench, Ashley I Beyer, Marina E Fomin, Rahul Thakker, Usha S Mulvaney, Masato Nakamura, Hiroshi Suemizu, Alicia Bárcena
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e97312 (2014)
The liver plays a vital role in hematopoiesis during mammalian prenatal development but its hematopoietic output declines during the perinatal period. Nonetheless, hepatic hematopoiesis is believed to persist into adulthood. We sought to model human
Externí odkaz:
https://doaj.org/article/6c4ceb1869984395a32fa1640edb59c6
Autor:
Terry Fei Fan Ng, Nikola O Kondov, Nobuhito Hayashimoto, Ritsuki Uchida, Yunhee Cha, Ashley I Beyer, Walt Wong, Patricia A Pesavento, Hiroshi Suemizu, Marcus O Muench, Eric Delwart
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66937 (2013)
Mice (Mus musculus) are the most commonly used laboratory animals. Viral metagenomics on tissues of immunodeficient mice revealed sequences of a novel mammalian astrovirus. Using PCR, we screened mice from 4 breeders, 4 pharmaceutical companies, 14 r
Externí odkaz:
https://doaj.org/article/26567e12e9d84a82bfb20561da592605
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77255 (2013)
Liver sinusoidal endothelial cells (LSECs) form a semi-permeable barrier between parenchymal hepatocytes and the blood. LSECs participate in liver metabolism, clearance of pathological agents, immunological responses, architectural maintenance of the
Externí odkaz:
https://doaj.org/article/291215665ce54326a19bfe280d7f97d0
Autor:
Marcus O. Muench, Marina E. Fomin, Alan G. Gutierrez, Dolores López-Terrada, Renata Gilfanova, Christopher Nosworthy, Ashley I. Beyer, Gregory Ostolaza, Dina Kats, Kevin L. Matlock, Stefano Cairo, Charles Keller
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Background & AimsHepatocytic cells found during prenatal development have unique features compared to their adult counterparts, and are believed to be the precursors of pediatric hepatoblastoma. The cell-surface phenotype of hepatoblasts and hepatobl
Externí odkaz:
https://doaj.org/article/a37e0996fedf4aec9268047863647657
Autor:
Graham Simmons, Marcus O. Muench, Ashley I. Beyer, Jean Publicover, Sonia Bakkour, Kai Lu, Marina E. Fomin
Publikováno v:
Cell medicine, vol 9, iss 3
The effects of sex on the degree of liver damage and human cell engraftment were investigated in immunodeficient urokinase-type plasminogen activator-transgenic (uPA-NOG) mice. Liver damage, measured by serum alanine transaminase (ALT) levels, was co
Autor:
Ashley I. Beyer, Daniel R. Potter, Gyulnar Baimukanova, Roberta Bruhn, Mitchell J. Cohen, Byron Miyazawa, Andrew P. Cap, Ali Danesh, Philip C. Spinella, Shibani Pati, Marcus O. Muench, Philip J. Norris, Yelena Dayter, Stuart L. Gibb, Sheila M. Keating
Publikováno v:
Transfusion. 56:S52-S64
Background Although a majority of the studies conducted to date on platelet (PLT) storage have been focused on PLT hemostatic function, the effects of 4°C PLTs on regulation of endothelial barrier permeability are still not known. In this study, we
Autor:
Ashley I. Beyer, Paul B. Contestable, Michael P. Busch, Fábio Fernandes, Antonio Luiz Pinho Ribeiro, Sheila M. Keating, Ester Cerdeira Sabino, Xutao Deng, B. Adesina, Brian Custer, Edecio Cunha-Neto
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Background Chagas disease has a long clinically silent period following Trypanosoma cruzi infection and before development of overt clinical pathology; detectable biomarkers of infection and pathogenesis are urgently needed. We tested 22 biomarkers k
Publikováno v:
Open Biology, Vol 7, Iss 12 (2017)
Open Biology
Open Biology
During prenatal development the liver is composed of multiple cell types with unique properties compared to their adult counterparts. We aimed to establish multilineage cultures of human fetal liver cells that could maintain stem cell and progenitor
Autor:
Alan G. Gutierrez, Zhongxia Qi, Kathryn L. Ponder, Mirhan Kapidzic, Haley Stolp, Susan J. Fisher, Marina E. Fomin, Ashley I. Beyer, Alicia Bárcena, Marcus O. Muench, Matthew Gormley
Publikováno v:
Development.
We examined the contribution of the fetal membranes, amnion and chorion, to human embryonic and fetal hematopoiesis. A population of cells displaying a hematopoietic progenitor phenotype (CD34++/+CD45low cells) of fetal origin was present in the chor