Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Ashley H. Choi"'
Autor:
Tianshu Feng, Jannik N. Andersen, Alan Huang, Yi Yu, Yingnan Chen, John P. Maxwell, Scott Throner, Douglas A. Whittington, Xuewen Pan, Erik Wilker, Minjie Zhang, Shanzhong Gong, Lina Gu, Fang Li, Truc V. Pham, Deepali Gotur, Lauren Martires, Binzhang Shen, Hongxiang Zhang, Ashley H. Choi, Samuel R. Meier, Shangtao Liu, Katherine Lazarides, Madhavi Bandi, Justin L. Engel, Antoine Simoneau
Supplementary Tables S1-S7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5312719b58a710c0222ed10b83c13e45
https://doi.org/10.1158/1535-7163.22523637
https://doi.org/10.1158/1535-7163.22523637
Autor:
Tianshu Feng, Jannik N. Andersen, Alan Huang, Yi Yu, Yingnan Chen, John P. Maxwell, Scott Throner, Douglas A. Whittington, Xuewen Pan, Erik Wilker, Minjie Zhang, Shanzhong Gong, Lina Gu, Fang Li, Truc V. Pham, Deepali Gotur, Lauren Martires, Binzhang Shen, Hongxiang Zhang, Ashley H. Choi, Samuel R. Meier, Shangtao Liu, Katherine Lazarides, Madhavi Bandi, Justin L. Engel, Antoine Simoneau
USP1 and PARP inhibition are synergistic in a BRCA1/2-dependent manner - related to Figure 4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8823edf17c22199a83a1e9bce21bf66
https://doi.org/10.1158/1535-7163.22523643
https://doi.org/10.1158/1535-7163.22523643
Autor:
Tianshu Feng, Jannik N. Andersen, Alan Huang, Yi Yu, Yingnan Chen, John P. Maxwell, Scott Throner, Douglas A. Whittington, Xuewen Pan, Erik Wilker, Minjie Zhang, Shanzhong Gong, Lina Gu, Fang Li, Truc V. Pham, Deepali Gotur, Lauren Martires, Binzhang Shen, Hongxiang Zhang, Ashley H. Choi, Samuel R. Meier, Shangtao Liu, Katherine Lazarides, Madhavi Bandi, Justin L. Engel, Antoine Simoneau
CRISPR-UMI analysis and characterization of PCNA dynamics - related to Figure 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ace5e56a67d70e4096c5a41d38520e58
https://doi.org/10.1158/1535-7163.22523646
https://doi.org/10.1158/1535-7163.22523646
Autor:
Tianshu Feng, Jannik N. Andersen, Alan Huang, Yi Yu, Yingnan Chen, John P. Maxwell, Scott Throner, Douglas A. Whittington, Xuewen Pan, Erik Wilker, Minjie Zhang, Shanzhong Gong, Lina Gu, Fang Li, Truc V. Pham, Deepali Gotur, Lauren Martires, Binzhang Shen, Hongxiang Zhang, Ashley H. Choi, Samuel R. Meier, Shangtao Liu, Katherine Lazarides, Madhavi Bandi, Justin L. Engel, Antoine Simoneau
Supplementary methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c764cc6d7f6554eddaf4cc9288f72c3
https://doi.org/10.1158/1535-7163.22523658.v1
https://doi.org/10.1158/1535-7163.22523658.v1
Autor:
Tianshu Feng, Jannik N. Andersen, Alan Huang, Yi Yu, Yingnan Chen, John P. Maxwell, Scott Throner, Douglas A. Whittington, Xuewen Pan, Erik Wilker, Minjie Zhang, Shanzhong Gong, Lina Gu, Fang Li, Truc V. Pham, Deepali Gotur, Lauren Martires, Binzhang Shen, Hongxiang Zhang, Ashley H. Choi, Samuel R. Meier, Shangtao Liu, Katherine Lazarides, Madhavi Bandi, Justin L. Engel, Antoine Simoneau
I-138 inhibits USP1-UAF1 - related to Figure 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88353d6c032f42bfab6a6b31c2e74be5
https://doi.org/10.1158/1535-7163.22523655.v1
https://doi.org/10.1158/1535-7163.22523655.v1
Autor:
Tianshu Feng, Jannik N. Andersen, Alan Huang, Yi Yu, Yingnan Chen, John P. Maxwell, Scott Throner, Douglas A. Whittington, Xuewen Pan, Erik Wilker, Minjie Zhang, Shanzhong Gong, Lina Gu, Fang Li, Truc V. Pham, Deepali Gotur, Lauren Martires, Binzhang Shen, Hongxiang Zhang, Ashley H. Choi, Samuel R. Meier, Shangtao Liu, Katherine Lazarides, Madhavi Bandi, Justin L. Engel, Antoine Simoneau
I-138 activity in BRCA1/2 WT and mutant cells - related to Figure 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08fbbd132593cd84e8647e692dae3dd7
https://doi.org/10.1158/1535-7163.22523652
https://doi.org/10.1158/1535-7163.22523652
Autor:
Tianshu Feng, Jannik N. Andersen, Alan Huang, Yi Yu, Yingnan Chen, John P. Maxwell, Scott Throner, Douglas A. Whittington, Xuewen Pan, Erik Wilker, Minjie Zhang, Shanzhong Gong, Lina Gu, Fang Li, Truc V. Pham, Deepali Gotur, Lauren Martires, Binzhang Shen, Hongxiang Zhang, Ashley H. Choi, Samuel R. Meier, Shangtao Liu, Katherine Lazarides, Madhavi Bandi, Justin L. Engel, Antoine Simoneau
CRISPR-UMI analysis of screens performed in NCI-H1693 cells - related to Figure 5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51e1b9d726e8dadf2858d500536964c7
https://doi.org/10.1158/1535-7163.22523640.v1
https://doi.org/10.1158/1535-7163.22523640.v1
Autor:
Antoine Simoneau, Justin L. Engel, Madhavi Bandi, Katherine Lazarides, Shangtao Liu, Samuel R. Meier, Ashley H. Choi, Hongxiang Zhang, Binzhang Shen, Lauren Martires, Deepali Gotur, Truc V. Pham, Fang Li, Lina Gu, Shanzhong Gong, Minjie Zhang, Erik Wilker, Xuewen Pan, Douglas A. Whittington, Scott Throner, John P. Maxwell, Yingnan Chen, Yi Yu, Alan Huang, Jannik N. Andersen, Tianshu Feng
Publikováno v:
Molecular cancer therapeutics.
CRISPR Cas9-based screening is a powerful approach for identifying and characterizing novel drug targets. Here, we elucidate the synthetic lethal mechanism of deubiquitinating enzyme USP1 in cancers with underlying DNA damage vulnerabilities, specifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::874e9cca43ea30bcc920747d496d8e35
https://pubmed.ncbi.nlm.nih.gov/36228090
https://pubmed.ncbi.nlm.nih.gov/36228090
Autor:
Jason T. Machan, Ashley H Choi, Benjamin J. Korry, Peter Belenky, Stella Ye Eun Lee, Collin Ganser, Amit K Chakrabarti
Publikováno v:
Antimicrob Agents Chemother
Mutagenesis is integral for bacterial evolution and the development of antibiotic resistance. Environmental toxins and stressors are known to elevate the rate of mutagenesis through direct DNA toxicity, known as stress-associated mutagenesis, or via
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71ba752f91554d49ad29385d9d2c21bd
https://europepmc.org/articles/PMC8448107/
https://europepmc.org/articles/PMC8448107/