Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Ashley Gomm"'
Autor:
Megan E. Bosch, Hemraj B. Dodiya, Julia Michalkiewicz, Choonghee Lee, Shabana M. Shaik, Ian Q. Weigle, Can Zhang, Jack Osborn, Aishwarya Nambiar, Priyam Patel, Samira Parhizkar, Xiaoqiong Zhang, Marie L. Laury, Prasenjit Mondal, Ashley Gomm, Matthew John Schipma, Dania Mallah, Oleg Butovsky, Eugene B. Chang, Rudolph E. Tanzi, Jack A. Gilbert, David M. Holtzman, Sangram S. Sisodia
Publikováno v:
Molecular Neurodegeneration, Vol 19, Iss 1, Pp 1-2 (2024)
Externí odkaz:
https://doaj.org/article/14d8b48203894334ae62b75a08c5835b
Autor:
Ping Bai, Yu Lan, Yan Liu, Prasenjit Mondal, Ashley Gomm, Yulong Xu, Yanli Wang, Yongle Wang, Leyi Kang, Lili Pan, Frederick A. Bagdasarian, Madelyn Hallisey, Fleur Lobo, Breanna Varela, Se Hoon Choi, Stephen N. Gomperts, Hsiao‐Ying Wey, Shiqian Shen, Rudolph E. Tanzi, Changning Wang, Can Zhang
Publikováno v:
Advanced Science, Vol 11, Iss 32, Pp n/a-n/a (2024)
Abstract Targeting receptor‐interacting protein kinase 1 (RIPK1) has emerged as a promising therapeutic stratagem for neurodegenerative disorders, particularly Alzheimer's disease (AD). A positron emission tomography (PET) probe enabling brain RIPK
Externí odkaz:
https://doaj.org/article/6a95c45a9c77468596a655055eef9238
Autor:
Megan E. Bosch, Hemraj B. Dodiya, Julia Michalkiewicz, Choonghee Lee, Shabana M. Shaik, Ian Q. Weigle, Can Zhang, Jack Osborn, Aishwarya Nambiar, Priyam Patel, Samira Parhizkar, Xiaoqiong Zhang, Marie L. Laury, Prasenjit Mondal, Ashley Gomm, Matthew John Schipma, Dania Mallah, Oleg Butovsky, Eugene B. Chang, Rudolph E. Tanzi, Jack A. Gilbert, David M. Holtzman, Sangram S. Sisodia
Publikováno v:
Molecular Neurodegeneration, Vol 19, Iss 1, Pp 1-26 (2024)
Abstract It has recently become well-established that there is a connection between Alzheimer’s disease pathology and gut microbiome dysbiosis. We have previously demonstrated that antibiotic-mediated gut microbiota perturbations lead to attenuatio
Externí odkaz:
https://doaj.org/article/5d6226d85e844091868e4f867d83ad18
Autor:
Piyali Saha, Ian Q. Weigle, Nicholas Slimmon, Pedro Blauth Poli, Priyam Patel, Xiaoqiong Zhang, Yajun Cao, Julia Michalkiewicz, Ashley Gomm, Can Zhang, Rudolph E. Tanzi, Nicholas Dylla, Ayman Al-Hendy, Sangram S. Sisodia
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract It is well-established that women are disproportionately affected by Alzheimer’s disease. The mechanisms underlying this sex-specific disparity are not fully understood, but several factors that are often associated-including interactions
Externí odkaz:
https://doaj.org/article/14fe3521416447db8bfd39910271f23f
Autor:
Prasenjit Mondal, Ping Bai, Ashley Gomm, Grisilda Bakiasi, Chih‐Chung Jerry Lin, Yanli Wang, Se Hoon Choi, Rudolph E. Tanzi, Changning Wang, Can Zhang
Publikováno v:
Advanced Science, Vol 11, Iss 1, Pp n/a-n/a (2024)
Abstract Histone deacetylase 6 (HDAC6) is one of the key histone deacetylases (HDACs) that regulates various cellular functions including clearance of misfolded protein and immunological responses. Considerable evidence suggests that HDAC6 is closely
Externí odkaz:
https://doaj.org/article/dc1603e8e7de47d08dce3a1227f667ad
Autor:
Ping Bai, Prasenjit Mondal, Frederick A. Bagdasarian, Nisha Rani, Yan Liu, Ashley Gomm, Darcy R. Tocci, Se Hoon Choi, Hsiao-Ying Wey, Rudolph E. Tanzi, Can Zhang, Changning Wang
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 12, Iss 10, Pp 3891-3904 (2022)
Although the epigenetic regulatory protein histone deacetylase 6 (HDAC6) has been recently implicated in the etiology of Alzheimer's disease (AD), little is known about the role of HDAC6 in the etiopathogenesis of AD and whether HDAC6 can be a potent
Externí odkaz:
https://doaj.org/article/fd064ae82b114df3b5e13bbc54ea4e17
Autor:
Gang Liu, Prasenjit Mondal, Na Sang, Zihua Li, Weihua Ding, Liuyue Yang, Yan Liu, Vishal C. Birar, Ashley Gomm, Rudolph E. Tanzi, Can Zhang, Shiqian Shen, Changning Wang, Xiaoxia Lu, Ping Bai
Publikováno v:
European Journal of Medicinal Chemistry. 254:115327
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3003e8dceaf7db94966baef0ff6e9fe
https://doi.org/10.1016/j.ejmech.2023.115327
https://doi.org/10.1016/j.ejmech.2023.115327