Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Ashley Geiger"'
Autor:
Gerasimos Konidaris, Diana Rofail, Jason Randall, Patrick R. LaFontaine, Chieh-I. Chen, Denise Bury, Ashley Geiger, Medha Sasane, Tara Symonds
Publikováno v:
Dermatology and Therapy, Vol 13, Iss 8, Pp 1747-1761 (2023)
Abstract Introduction Evidence of patients’ experiences of living with advanced basal cell carcinoma (aBCC) are limited, particularly after hedgehog pathway inhibitor (HHI) treatment. We explored the burden of aBCC on symptoms and patients’ every
Externí odkaz:
https://doaj.org/article/1e987f0f944244feafbc97352b5c0275
Autor:
Kajal Chaudhry, Ashley Geiger, Ehsan Dowlati, Haili Lang, Danielle K. Sohai, Eugene I. Hwang, Christopher A. Lazarski, Eric Yvon, Matthias Holdhoff, Richard Jones, Barbara Savoldo, Conrad Russell Y. Cruz, Catherine M. Bollard
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 27, Iss , Pp 415-430 (2022)
Cord blood (CB)-derived natural killer (NK) cells that are genetically engineered to express a chimeric antigen receptor (CAR) are an attractive off-the-shelf therapy for the treatment of cancer, demonstrating a robust safety profile in vivo. For poo
Externí odkaz:
https://doaj.org/article/2478a16e444f4187b1167f6bf2ee7d0f
Autor:
Mariah Jensen-Wachspress, Peter D. Burbelo, Kathleen Webber, Conrad Russell Y. Cruz, Catherine M. Bollard, Michael D. Keller, Ashley Geiger, Haili Lang, Jeffrey I. Cohen, Danielle Sohai, Christopher A. Lazarski, Brita Ostermeier, Maja Stanojevic
Publikováno v:
Cytotherapy
Although most studies describing coronavirus disease 2019 vaccine responses have focused on antibodies, there is increasing evidence that T cells play a critical role. Here the authors evaluated T-cell responses in seronegative donors before and afte
Autor:
Patrick J. Hanley, Amy B. Hont, Catherine M. Bollard, Samuel O'Brien, Maja Stanojevic, Robert Ulrey, A. John Barrett, Conrad Russell Y. Cruz, Ashley Geiger, Haili Lang, Melanie Grant, Ping-Hsien Lee, Michael D. Keller, Anushree Datar
Publikováno v:
Cytotherapy
Background aims Preferentially expressed antigen in melanoma (PRAME) is a cancer/testis antigen that is overexpressed in many human malignancies and poorly expressed or absent in healthy tissues, making it a good target for anti-cancer immunotherapy.
Autor:
Ashley Geiger, Hua Liang, Jessica Durkee-Shock, Catherine M. Bollard, Allistair Abraham, C. Russell Cruz, Eva M. Stevenson, Patrick J. Hanley, Fahmida Hoq, R. Brad Jones, Maja Stanojevic, Christopher A. Lazarski, Anushree Datar, Kajal Chaudhry, Zoe Shancer, Haili Lang, Jeffrey I. Cohen, Emily K. Reynolds, Mariah Jensen-Wachspress, Madeline Terpilowski, Ping-Hsien Lee, Kathleen Webber, Robert Ulrey, Kathleen Ferrer, Vaishnavi V. Kankate, Krista Gangler, Katherine M. Harris, Nan Zhang, Stéphanie Val, Peter D. Burbelo, Uduak Ekanem, Michael D. Keller, Lesia K. Dropulic
Publikováno v:
Blood
T-cell responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been described in recovered patients, and may be important for immunity following infection and vaccination as well as for the development of an adoptive immunother
Autor:
Eugene Hwang, Fernanda Fortiz, Russell Cruz, Ashley Geiger, Melanie Grant, Haili Lang, Abeer Shibli, Sianna Burnett, Chris Lazarski, Jay Tanna, Chase McCann, Fahmida Hoq, Patrick Hanley, Lindsay Kilburn, Brian Rood, Roger Packer, Catherine Bollard
Publikováno v:
Neuro-Oncology. 24:i85-i86
BACKGROUND: The ReMIND trial hypothesizes that autologous T-cells specific for three tumor-associated antigens (TAA) -WT1, PRAME, and survivin- will be safe and elicit anti-tumor immunity in pediatric patients with CNS cancer. METHODS: Patients (n=25
Autor:
Kajal Chaudhry, Ehsan Dowlati, Mark D. Long, Ashley Geiger, Haili Lang, Eduardo C. Gomez, Nethaji Muniraj, Carlos E. Sanchez, Prashant K. Singh, Song Liu, Catherine M. Bollard, Conrad Russell Y. Cruz
Publikováno v:
Cytotherapy. 24(8)
T cell-based therapies like genetically modified immune cells expressing chimeric antigen receptors have shown robust anti-cancer activity in vivo, especially in patients with blood cancers. However, extending this approach to an "off-the-shelf" sett
Autor:
Madeline Terpilowski, Vaishnavi V. Kankate, Jeffrey I. Cohen, Krista Gangler, Zoe Shancer, Jessica Durkee-Shock, Katherine M. Harris, Ping-Hsien Lee, Anushree Datar, Fahmida Hoq, Catherine M. Bollard, Russell Cruz, Kathleen Webber, Stéphanie Val, Christopher A. Lazarski, Ashley Geiger, Peter D. Burbelo, Emily K. Reynolds, Nan Zhang, Eva M. Stevenson, Kajal Chaudhry, Hua Liang, Maja Stanojevic, Susan Conway, Michael D. Keller, Patrick J. Hanley, R. Brad Jones, Alister Abraham, Haili Lang, Mariah Jensen-Wachspress, Lesia K. Dropulic
Publikováno v:
Transplantation and Cellular Therapy
Autor:
Melanie Grant, Maria Fortiz, Lu Wang, Haili Lang, Anushree Datar, Emily Reynolds, Madeleine Terpilowski, Ashley Geiger, Chris Lazarski, Jay Tanna, Adriana Pitino, Nan Zhang, Fahmida Hoq, Patrick Hanley, C Russell Cruz, Lindsay Kilburn, Roger Packer, Brian Rood, Catherine Bollard
Publikováno v:
Neuro-Oncology
Background Patients with relapsed CNS malignancies or DIPG face terrible prognoses. We hypothesized that T cells specific for 3 tumor-associated antigens (TAA), WT1, PRAME and survivin, would be safe and elicit anti-tumor immunity. Methods Patients (
Autor:
Robert Ulrey, C.Y. Cruz, S. O'Brien, Maja Stanojevic, Michael D. Keller, Patrick J. Hanley, Catherine M. Bollard, Ashley Geiger
Publikováno v:
Cytotherapy. 22:S136-S137
Background & Aim Preferentially expressed antigen in melanoma (PRAME) is a cancer-testis antigen that is overexpressed in many human malignancies while poorly expressed or absent in healthy tissues, making it a good target for anticancer immunotherap