Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Ashley E Landuyt"'
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0196591 (2018)
Dendritic cells (DC) are sentinels of the immune system, alerting and enlisting T cells to clear pathogenic threats. As such, numerous studies have demonstrated their effective uptake and proteolytic activities coupled with antigen processing and pre
Externí odkaz:
https://doaj.org/article/b51a24e870d9428fa26b8f995c34d429
Autor:
Yun Kyung Lee, Ashley E Landuyt, Stefani Lobionda, Panida Sittipo, Qing Zhao, Craig L Maynard
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0186351 (2017)
The development of Th17 cells is accompanied by the acquisition of responsiveness to both IL-12 and IL-23, cytokines with established roles in the development and/or function of Th1 and Th17 cells, respectively. IL-12 signaling promotes antigen-depen
Externí odkaz:
https://doaj.org/article/0a3cd2029dd545a7920aa129bd83b265
Autor:
Virginia Camacho, Victoria R. Matkins, Sweta B. Patel, Jeremie M. Lever, Zhengqin Yang, Li Ying, Ashley E. Landuyt, Emma C. Dean, James F. George, Henry Yang, Paul Brent Ferrell, Craig L. Maynard, Casey T. Weaver, Heth R. Turnquist, Robert S. Welner
Publikováno v:
JCI Insight, Vol 5, Iss 22 (2020)
The nonimmune roles of Tregs have been described in various tissues, including the BM. In this study, we comprehensively phenotyped marrow Tregs, elucidating their key features and tissue-specific functions. We show that marrow Tregs are migratory an
Externí odkaz:
https://doaj.org/article/1f60283a5d9849e4826f16038c6c5f98
Publikováno v:
The Journal of Immunology. 202:1039-1044
The ICOS pathway has been implicated in the development and functions of regulatory T (Treg) cells, including those producing IL-10. Treg cell–derived IL-10 is indispensable for the establishment and maintenance of intestinal immune homeostasis. We
Autor:
Melissa S Jennings, Barbara J. Klocke, Keri M. Kemp, Hubert M. Tse, L.W. Duck, Craig L. Maynard, Casey D. Morrow, Charles O. Elson, Rachel Q Muir, Goo Lee, Ashley E. Landuyt, Samuel I. Blum
Publikováno v:
Proc Natl Acad Sci U S A
Genome-wide association studies have identified ICOSLG, which encodes the inducible costimulator ligand (ICOSLG or ICOSL) as a susceptibility locus for inflammatory bowel disease. ICOSL has been implicated in the enhancement of pattern recognition re
Autor:
Sweta B. Patel, Emma C. Dean, Ashley E. Landuyt, Henry Yang, Victoria R. Matkins, Craig L. Maynard, Jeremie M. Lever, Li Ying, James F. George, Paul Brent Ferrell, Virginia Camacho, Robert S. Welner, Casey T. Weaver, Heth R. Turnquist, Zhengqin Yang
Publikováno v:
JCI Insight
JCI Insight, Vol 5, Iss 22 (2020)
JCI Insight, Vol 5, Iss 22 (2020)
The nonimmune roles of Tregs have been described in various tissues, including the BM. In this study, we comprehensively phenotyped marrow Tregs, elucidating their key features and tissue-specific functions. We show that marrow Tregs are migratory an
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 202(4)
The ICOS pathway has been implicated in the development and functions of regulatory T cells (Treg cells) including those producing IL-10. Treg cell-derived IL-10 is indispensable for the establishment and maintenance of intestinal immune homeostasis.
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 5, p e0196591 (2018)
PLoS ONE, Vol 13, Iss 5, p e0196591 (2018)
Dendritic cells (DC) are sentinels of the immune system, alerting and enlisting T cells to clear pathogenic threats. As such, numerous studies have demonstrated their effective uptake and proteolytic activities coupled with antigen processing and pre
Synergy between T-dependent antibodies and IL-10 limits susceptibility to inflammatory bowel disease
Publikováno v:
The Journal of Immunology. 202:192.20-192.20
Inflammatory bowel diseases (IBD) are chronic autoinflammatory conditions in which the immune system loses tolerance to gastrointestinal microbes. The role of humoral immunity in IBD is largely undefined. We examined the potential of T-dependent anti
Autor:
Ashley E. Landuyt, Qing Zhao, Panida Sittipo, Stefani Lobionda, Yun Kyung Lee, Craig L. Maynard
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 10, p e0186351 (2017)
PLoS ONE, Vol 12, Iss 10, p e0186351 (2017)
The development of Th17 cells is accompanied by the acquisition of responsiveness to both IL-12 and IL-23, cytokines with established roles in the development and/or function of Th1 and Th17 cells, respectively. IL-12 signaling promotes antigen-depen