Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Ashley Chabot"'
Autor:
Antonio Morales‐Hernández, Emilia Kooienga, Heather Sheppard, Gabriela Gheorghe, Claire Caprio, Ashley Chabot, Shannon McKinney‐Freeman
Publikováno v:
HemaSphere, Vol 8, Iss 11, Pp n/a-n/a (2024)
Abstract Gprasp1 and Gprasp2 encode proteins that control the stability and cellular trafficking of CXCR4, a master regulator of hematopoiesis whose dynamic regulation is required for appropriate trafficking of B‐cells in the germinal center (GC).
Externí odkaz:
https://doaj.org/article/8b30adbd1ee045e590f6be2052c79d45
Autor:
Lindsay Jones Talbot, Ashley Chabot, Amy Funk, Phuong Nguyen, Jessica Wagner, Aaron Ross, Heather Tillman, Andrew Davidoff, Stephen Gottschalk, Christopher DeRenzo
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The outcome for metastatic pediatric osteosarcoma (OS) remains poor. Thus, there is an urgent need to develop novel therapies, and immunotherapy with CAR T cells has the potential to meet this challenge. However, there is a lack of preclinical models
Externí odkaz:
https://doaj.org/article/ced770436fb748028e4dab2bed3ec06b
Autor:
Miguel Ganuza, Ashley Chabot, Xing Tang, Wenjian Bi, Sivaraman Natarajan, Robert Carter, Charles Gawad, Guolian Kang, Yong Cheng, Shannon McKinney-Freeman
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
The source of where definitive hematopoietic stem cells (dHSCs) develop in the mouse embyro has been much debated. Here, the authors identify that dHSCs arise from the intra-embyronic region by using murine embryonic explant transplantation but not f
Externí odkaz:
https://doaj.org/article/7973eb1e655f4fbfabc98a89df0a89fe
Autor:
Antonio Morales-Hernández, Alice Martinat, Ashley Chabot, Guolian Kang, Shannon McKinney-Freeman
Publikováno v:
Stem Cell Reports, Vol 11, Iss 2, Pp 334-347 (2018)
Summary: C57BL/6N (N) and C57BL/6J (J) mice possess key genetic differences, including a deletion in the Nicotinamide nucleotide transhydrogenase (Nnt) gene that results in a non-functional protein in J mice. NNT regulates mitochondrial oxidative str
Externí odkaz:
https://doaj.org/article/c16a3b48638a454caa8542b32034bba9
Autor:
Miguel Ganuza, Trent Hall, Jacquelyn Myers, Chris Nevitt, Raúl Sánchez-Lanzas, Ashley Chabot, Juan Ding, Emilia Kooienga, Claire Caprio, David Finkelstein, Guolian Kang, Esther Obeng, Shannon McKinney-Freeman
Publikováno v:
Nat Cell Biol
Current dogma asserts that the foetal liver (FL) is an expansion niche for recently specified haematopoietic stem cells (HSCs) during ontogeny. Indeed, between embryonic day of development (E)12.5 and E14.5, the number of transplantable HSCs in the m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8319a9bcccf5ffef3ad6ee8e266c3b19
https://europepmc.org/articles/PMC10026622/
https://europepmc.org/articles/PMC10026622/
Autor:
Christopher DeRenzo, Lindsay J. Talbot, Stephen Gottschalk, Amy J. Funk, Aaron Ross, Heather Tillman, Ashley Chabot, Jessica Wagner, Phuong Nguyen, Andrew M. Davidoff
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology, Vol 12 (2021)
The outcome for metastatic pediatric osteosarcoma (OS) remains poor. Thus, there is an urgent need to develop novel therapies, and immunotherapy with CAR T cells has the potential to meet this challenge. However, there is a lack of preclinical models
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::587da69f68df8369f7d732d901dbdc5d
http://europepmc.org/articles/PMC8239305
http://europepmc.org/articles/PMC8239305
Autor:
Antonio Morales-Hernández, Chaïma Benaksas, Maheen Ferdous, Guolian Kang, Shannon McKinney-Freeman, Claire Caprio, Xiwen Zhao, Ashley Chabot
Publikováno v:
Blood
Hematopoietic stem cell (HSC) transplantation (HSCT) is often exploited to treat hematologic disease. Donor HSCs must survive, proliferate, and differentiate in the damaged environment of the reconstituting niche. Illuminating molecular mechanisms re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78ce9cd2894f653c5e7d4b9b78fabcbb
https://europepmc.org/articles/PMC7118811/
https://europepmc.org/articles/PMC7118811/
Autor:
Alice Martinat, Shannon McKinney-Freeman, Antonio Morales-Hernández, Ashley Chabot, Guolian Kang
Publikováno v:
Stem Cell Reports, Vol 11, Iss 2, Pp 334-347 (2018)
Stem Cell Reports
Stem Cell Reports
Summary C57BL/6N (N) and C57BL/6J (J) mice possess key genetic differences, including a deletion in the Nicotinamide nucleotide transhydrogenase (Nnt) gene that results in a non-functional protein in J mice. NNT regulates mitochondrial oxidative stre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e207358c45748cd366031dda80dfdc34
http://www.sciencedirect.com/science/article/pii/S2213671118302741
http://www.sciencedirect.com/science/article/pii/S2213671118302741
Autor:
Antonio Morales-Hernández, Emilia Kooienga, Heather Tillman, Claire Caprio, Ashley Chabot, Laura Pasqualucci, Shannon McKinney-Freeman
Publikováno v:
Experimental Hematology. 100:S55
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c0e90e23ff3c4705ccfc8d1c2b45f40
https://doi.org/10.1016/j.exphem.2021.12.247
https://doi.org/10.1016/j.exphem.2021.12.247
Autor:
David Finkelstein, Ashley Chabot, Guolian Kang, Shannon McKinney-Freeman, Miguel Ganuza, Wenjian Bi, Trent Hall, Gang Wu, Yong-Dong Wang
Publikováno v:
Blood
Although many recent studies describe the emergence and prevalence of “clonal hematopoiesis of indeterminate potential” in aged human populations, a systematic analysis of the numbers of clones supporting steady-state hematopoiesis throughout mam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed529ac41e767103a04597c4939c9048
https://europepmc.org/articles/PMC6497513/
https://europepmc.org/articles/PMC6497513/