Výsledky vyhledávání - "Ashley Callinan"

Abstract LB318: SB-4826, a first-in-class oral, covalent inhibitor of SUMO E1 that induces IFN signaling and inhibits tumor growth as monotherapy and in combination with immune checkpoint blockade

Autor: Jude R. Canon, Ashley Callinan, Sarah Bradley, Laurie Wang, Mackenzie Kui, Ariel Wein, Gabriele Sulli, Peter Buchowiecki, Fang-Tsao Hong, Miles Kubota, Mary Walton, Victor J. Cee

Publikováno v: Cancer Research. 83:LB318-LB318

Sumoylation is a reversible post-translational modification of proteins by small ubiquitin-like modifier (SUMO) that regulates protein function and contributes to cellular response to stress. Sumoylation is an essential pathway for all cells and is i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::29a9c968056ed63643aa28630abd9091
https://doi.org/10.1158/1538-7445.am2023-lb318

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