Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Ashley Bill"'
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 141, Iss , Pp 111852- (2021)
Brief introduction: The synthetic compound enaminone E121 has an established role as a potent anti-tussive, bronchodilator and anti-inflammatory agent in asthma, cough, and colitis induced animal models. The addition of an N-alkylated piperazine moti
Externí odkaz:
https://doaj.org/article/edc55132050242ceb18dcf204ce8ede1
Autor:
Doreen E. Szollosi, Junjiang Sun, Baolai Hua, Ivan O. Edafiogho, Ashley Bill, Chen Zhong, Yingping Zhuang, Ola Ghoneim
Publikováno v:
Inflammation. 42:1719-1729
Hemarthrosis is the primary cause of hemophiliac arthropathy (HA). Pro-inflammatory cytokines are thought to play an important role in the pathogenesis of HA, and thus, anti-cytokine approaches may be used as an adjuvant therapy. A novel series of en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d05e273c725cdcc5fa88f5cb1d37d28c
https://doi.org/10.1007/s10753-019-01032-y
https://doi.org/10.1007/s10753-019-01032-y
Autor:
Sanaa Hawai, Ashley Bill, Ola Ghoneim, Doreen E. Szollosi, Maitham A. Khajah, Ivan O. Edafiogho
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 141, Iss, Pp 111852-(2021)
Brief introduction The synthetic compound enaminone E121 has an established role as a potent anti-tussive, bronchodilator and anti-inflammatory agent in asthma, cough, and colitis induced animal models. The addition of an N-alkylated piperazine motif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52c1bb0518a9435d7c3f8ee5b5a935b9
https://doi.org/10.1016/j.biopha.2021.111852
https://doi.org/10.1016/j.biopha.2021.111852
Autor:
Ashley Bill, Doreen E. Szollosi
Publikováno v:
Current drug targets. 21(2)
Background: Influenza is a single-stranded RNA virus that is highly contagious and infects millions of people in the U.S. annually. Due to complications, approximately 959,000 people were hospitalized and another 79,400 people died during the 2017-20
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2cccea4d9e21e54370b8faafdbd32ec
https://pubmed.ncbi.nlm.nih.gov/31368872
https://pubmed.ncbi.nlm.nih.gov/31368872
Publikováno v:
Journal of Chemical Education. 94:1388-1390
The addition of a nucleophilic functional group to an electron-deficient aromatic ring is a versatile reaction in the modern organic chemistry arsenal. The proper positioning of a leaving group on this ring effectively allows for a substitution react
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd3d3fae12a6d0b37519d63e1faae19c
https://doi.org/10.1021/acs.jchemed.6b00680
https://doi.org/10.1021/acs.jchemed.6b00680
Autor:
Doreen E Szollosi, Maitham Khajah, Sanaa Hawai, Ola Ghoneim, Ashley Bill, Mallory Daniels-Monk, Ivan O. Edafiogho
Publikováno v:
The Journal of Immunology. 204:238.24-238.24
Crohn’s disease and ulcerative colitis are two disorders categorized as inflammatory bowel diseases (IBD). Patients with IBD may have inflammation extending the full thickness of the gut and non-gut organs mediated in part by Th-induced cytokines I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3333a331cc3a3862f742ff225016765b
https://doi.org/10.4049/jimmunol.204.supp.238.24
https://doi.org/10.4049/jimmunol.204.supp.238.24
Publikováno v:
Bioorganicmedicinal chemistry. 26(14)
Infection triggers the release of pro-inflammatory cytokines (TNF-alpha and IL-6). Over-production, however, cause tissue injury seen in severe asthma. The ability of enaminone E121 to reduce pro-inflammatory cytokines in our laboratory encouraged fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29a67e681ae57a16867369593dc6322f
https://pubmed.ncbi.nlm.nih.gov/29903412
https://pubmed.ncbi.nlm.nih.gov/29903412
Publikováno v:
The Journal of Immunology. 200:54.15-54.15
Data to characterize novel anti-inflammatory agent enaminone E121 have shown a marked decrease in the release of pro-inflammatory cytokines in macrophages stimulated with lipopolysaccharide (LPS) compared to the control (DMSO) group. Literature has d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7765a229f31de414f92356c25ee8f96
https://doi.org/10.4049/jimmunol.200.supp.54.15
https://doi.org/10.4049/jimmunol.200.supp.54.15
Publikováno v:
Journal of College Orientation, Transition, and Retention, Vol 29, Iss 2 (2022)
Despite the fact that more Black students than ever pursue graduate education, the experiences of Black graduate students in higher education and student affairs programs leave much to be discovered. This work aims to shed light on the interconnectio
Externí odkaz:
https://doaj.org/article/e876ffbc47b24b54a5587fa22598ab0f
Autor:
Burton, Paul, Philips, Aaron, Hazzard, Jack, Bollands, David, Sweet, Maggie, Nichols, Pat, Strange, Paul, Rowsell, Charlotte, Parkinson, Alastair, Jackson, Lee, Healy, Paul, McQuillan, Richie, Barber, Paul, Roswell, Tim, Levine, Jennie, Wheatley, Simon, Ashley, Bill, Page, Eric
Publikováno v:
Four Four Two; Oct2008, p11-14, 3p