Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Ashley Allshire"'
Autor:
Ashley Allshire, Peter H. Cobbold
Publikováno v:
Isolated Adult Cardiomyocytes ISBN: 9780429290541
Isolated Adult Cardiomyocytes
Isolated Adult Cardiomyocytes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e63a54bd192a4ccc5a53c4f2cc5e9fc7
https://doi.org/10.1201/9780429290541-12
https://doi.org/10.1201/9780429290541-12
Autor:
Shailendra Anoopkumar-Dukie, T. Conere, Catherine McDermott, Aileen Houston, Liam King, David R. H. Christie, Ashley Allshire
Publikováno v:
Prostaglandins & Other Lipid Mediators. 148:106422
It is widely accepted that the hypoxic nature of solid tumors contribute to their resistance to radiation therapy. There is increasing evidence that cyclooxygenase-2 (COX-2) contributes to increased resistance of tumors to radiation therapy. Several
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f93d7d5d2b64ef8101fa7daa01ec6d6a
https://doi.org/10.1016/j.prostaglandins.2020.106422
https://doi.org/10.1016/j.prostaglandins.2020.106422
Publikováno v:
The British Journal of Radiology. 82:847-854
Oxygen-dependent radiosensitivity of tumour cells reflects direct oxidative damage to DNA, but non-nuclear mechanisms including signalling pathways may also contribute. Mitochondria are likely candidates because not only do they integrate signals fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44f0947d11bf4c128498c8a907b20816
https://doi.org/10.1259/bjr/35746067
https://doi.org/10.1259/bjr/35746067
Publikováno v:
Toxicological Sciences. 101:263-274
Humans are frequently exposed to mixtures of environmental pollutants at low levels over prolonged periods of time yet most toxicity studies deal with acute exposure to high concentrations of single chemicals. Investigation of the biological effects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::530bfd44ad4b34c9d0472719064437f6
https://doi.org/10.1093/toxsci/kfm274
https://doi.org/10.1093/toxsci/kfm274
Publikováno v:
Toxicology and Applied Pharmacology. 219:85-94
Organic solvents form an important class of pollutants in the ambient air and have been associated with neurotoxicity and immunotoxicity in humans. Here we investigated the biological effects of sub-chronic exposure to industrially important volatile
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47a1160fe4cd8b83e28e502d1819cb06
https://doi.org/10.1016/j.taap.2006.12.004
https://doi.org/10.1016/j.taap.2006.12.004
Publikováno v:
Toxicological Sciences. 91:113-122
Immune modulation by heavy metals may cause serious adverse health effects in humans, although the mechanisms involved are not well understood. Both cadmium and lead are important environmental and occupational toxins. Therefore, in the current study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f734e1fd221221a3818ce29dfe3dd51
https://doi.org/10.1093/toxsci/kfj142
https://doi.org/10.1093/toxsci/kfj142
Publikováno v:
The British Journal of Radiology. 78:335-337
In this study we assessed cell response to ionizing radiation doses in the diagnostic X-ray range, using metabolic performance as the biological end point. HeLa cells were irradiated between 3.5 mGy (standard deviation (SD=2.5%) and 55.1 mGy (SD=0.9%
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6cbc0abc31df6ebc957dec71cdfd57b
https://doi.org/10.1259/bjr/24426084
https://doi.org/10.1259/bjr/24426084
Publikováno v:
Journal of Molecular and Cellular Cardiology. 24:213-218
The sequence of events that leads to irreversible injury of the ischaemic myocardium is poorly understood but it is axiomatic that lack of oxygen will impair regeneration of ATP. In the globally-ischaemic heart a contracture develops which is indepen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::220a2d267586c56efffa829eb73394d5
https://doi.org/10.1016/0022-2828(92)93159-h
https://doi.org/10.1016/0022-2828(92)93159-h
Publikováno v:
Toxicology in vitro : an international journal published in association with BIBRA. 21(1)
In vitro assessment of organic solvents can be problematic as the volatile nature of these compounds makes maintaining a constant exposure level difficult. However, a stable exposure level must be maintained if reliable dose response data are to be o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::051df6c0e9d4bac5ad490c79e5a08345
https://pubmed.ncbi.nlm.nih.gov/17045455
https://pubmed.ncbi.nlm.nih.gov/17045455
Autor:
Yury Ladilov, B. Siegmund, Ashley Allshire, Hans Michael Piper, Klaus-Dieter Schlüter, David Garcia-Dorado
Publikováno v:
Fibrinolysis and Proteolysis. 11:113-115
Summary In ischemic-reperfused myocardium severe cellular injury may develop rapidly upon re-oxygenation (‘oxygen paradox’). Several causes of this acute form of reperfusion injury have now been identified. During oxygen depletion cardiomyocytes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::213c8eab9aa783c9a92e96d4ebbb9698
https://doi.org/10.1016/s0268-9499(97)80081-1
https://doi.org/10.1016/s0268-9499(97)80081-1