Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Ashley A. Stegelmeier"'
Autor:
Yeganeh Mehrani, Jason P. Knapp, Julia E. Kakish, Sophie Tieu, Helia Javadi, Lily Chan, Ashley A. Stegelmeier, Christina Napoleoni, Byram W. Bridle, Khalil Karimi
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 18, p 14141 (2023)
Mat cells (MCs) are located in the skin and mucous membranes at points where the body meets the environment. When activated, MCs release inflammatory cytokines, which help the immune system to fight viruses. MCs produce, and have receptors for interf
Externí odkaz:
https://doaj.org/article/63e293a0166f45038e608e3a9fedee1a
Autor:
Amanda W. K. AuYeung, Robert C. Mould, Ashley A. Stegelmeier, Jacob P. van Vloten, Khalil Karimi, J. Paul Woods, James J. Petrik, Geoffrey A. Wood, Byram W. Bridle
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Vaccination can prevent viral infections via virus-specific T cells, among other mechanisms. A goal of oncolytic virotherapy is replication of oncolytic viruses (OVs) in tumors, so pre-existing T cell immunity against an OV-encoded transgene
Externí odkaz:
https://doaj.org/article/cc74d8086b614168938f0bb79a7adef3
Publikováno v:
Plants, Vol 11, Iss 20, p 2783 (2022)
Improvements to the world’s food supply chain are needed to ensure sufficient food is produced to meet increasing population demands. Growing food in soilless hydroponic systems constitutes a promising strategy, as this method utilizes significantl
Externí odkaz:
https://doaj.org/article/2ae903f2603441b7a1a1eaf50436c847
Publikováno v:
mSystems, Vol 6, Iss 4 (2021)
ABSTRACT Although previous research demonstrates that skin-associated archaea are rarely detected within human skin microbiome data, exist at relatively low abundance, and are primarily affiliated with the Methanobacteriota and Halobacteriota phyla,
Externí odkaz:
https://doaj.org/article/32ca428366c3420eb2978dfae68aa4c3
Autor:
Ashley A. Stegelmeier, Lisa A. Santry, Matthew M. Guilleman, Kathy Matuszewska, Jessica A. Minott, Jacob G. E. Yates, Brenna A. Y. Stevens, Sylvia P. Thomas, Sierra Vanderkamp, Kiersten Hanada, Yanlong Pei, Amira D. Rghei, Jacob P. van Vloten, Madison Pereira, Brad Thompson, Pierre P. Major, James J. Petrik, Byram W. Bridle, Sarah K. Wootton
Publikováno v:
Biomedicines, Vol 10, Iss 2, p 362 (2022)
Epithelial ovarian cancer is the deadliest gynecological malignancy. The lack of effective treatments highlights the need for novel therapeutic interventions. The aim of this study was to investigate whether sustained adeno-associated virus (AAV) vec
Externí odkaz:
https://doaj.org/article/b7a933055d294583b0ee729eeada2323
Autor:
Lily Chan, Kasra Alizadeh, Kimia Alizadeh, Fatemeh Fazel, Julia E. Kakish, Negar Karimi, Jason P. Knapp, Yeganeh Mehrani, Jessica A. Minott, Solmaz Morovati, Amira Rghei, Ashley A. Stegelmeier, Sierra Vanderkamp, Khalil Karimi, Byram W. Bridle
Publikováno v:
Vaccines, Vol 9, Iss 9, p 979 (2021)
Influenza viruses have affected the world for over a century, causing multiple pandemics. Throughout the years, many prophylactic vaccines have been developed for influenza; however, these viruses are still a global issue and take many lives. In this
Externí odkaz:
https://doaj.org/article/ce51ce7fef0747f8985608b62f70e1dc
Autor:
Ashley A. Stegelmeier, Maedeh Darzianiazizi, Kiersten Hanada, Shayan Sharif, Sarah K. Wootton, Byram W. Bridle, Khalil Karimi
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 9, p 4726 (2021)
Interferons (IFNs) are induced by viruses and are the main regulators of the host antiviral response. They balance tissue tolerance and immune resistance against viral challenges. Like all cells in the human body, neutrophils possess the receptors fo
Externí odkaz:
https://doaj.org/article/cc0c1590ca1f452f83f2cb8af630d15a
Autor:
Ashley A. Stegelmeier, Lily Chan, Yeganeh Mehrani, James J. Petrik, Sarah K. Wootton, Byram Bridle, Khalil Karimi
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 17, p 6347 (2020)
Neutrophils are innate leukocytes that mount a rapid response to invading pathogens and sites of inflammation. Although neutrophils were traditionally considered responders to bacterial infections, recent advances have demonstrated that they are inte
Externí odkaz:
https://doaj.org/article/7dc2f52798b84c5fa527191551c3a9fc
Autor:
Ashley A. Stegelmeier, Jacob P. van Vloten, Robert C. Mould, Elaine M. Klafuric, Jessica A. Minott, Sarah K. Wootton, Byram W. Bridle, Khalil Karimi
Publikováno v:
Viruses, Vol 11, Iss 2, p 168 (2019)
Myeloid cells represent a diverse range of innate leukocytes that are crucial for mounting successful immune responses against viruses. These cells are responsible for detecting pathogen-associated molecular patterns, thereby initiating a signaling c
Externí odkaz:
https://doaj.org/article/7deba92fcd1a4fb28a1fb17e052e5fdb
Autor:
Anthony J. Mutsaers, Samuel E. Hocker, R. Darren Wood, Geoffrey A. Wood, Byram W. Bridle, Christopher J Pinard, Ashley A. Stegelmeier, J. Paul Woods
Publikováno v:
Veterinary and Comparative Oncology. 20:427-436
Urothelial carcinoma (UC) is the most common urinary tumour in dogs. Despite a range of treatment options, prognosis remains poor in dogs. In people, breakthroughs with checkpoint inhibitors have established new standards of care for muscle-invasive