Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Ashley A. Chapin"'
Publikováno v:
Methods and Protocols, Vol 6, Iss 1, p 6 (2023)
Serotonin (5-HT) is a neurotransmitter involved in many biophysiological processes in the brain and in the gastrointestinal tract. Electrochemical methods are commonly used to quantify 5-HT, but their reliability may suffer due to the time-dependent
Externí odkaz:
https://doaj.org/article/fbe8cd4f79744eb484aa0f4e9a3d33b1
Autor:
Mitul Desai, Jitendra Sharma, Adrian L Slusarczyk, Ashley A Chapin, Robert Ohlendorf, Agata Wisniowska, Mriganka Sur, Alan Jasanoff
Publikováno v:
eLife, Vol 10 (2021)
Molecular imaging could have great utility for detecting, classifying, and guiding treatment of brain disorders, but existing probes offer limited capability for assessing relevant physiological parameters. Here, we describe a potent approach for non
Externí odkaz:
https://doaj.org/article/774209b04a9c4770b8e7b90486ab4440
Publikováno v:
Analytical Methods. 15:1096-1104
We developed a novel electrochemical sensing platform consisting of a surface-modified carbon-fiber microelectrode and portable potentiostat electronics for rapid serotonin (5-HT) detection in artificial biological fluids.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6c28913642d00ecce7ac7826dc86f66
https://doi.org/10.1039/d2ay01627c
https://doi.org/10.1039/d2ay01627c
Publikováno v:
Journal of Microelectromechanical Systems. 29:727-733
This work presents an integrated electrochemical and electrophysiological biomonitoring system, enabling the study of molecular signaling along the gut-brain-axis (GBA). In vitro gut cell cultures provide a controllable, accessible platform to study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c68262a94eed2c3015a25bf74b33504b
https://doi.org/10.1109/jmems.2020.3000392
https://doi.org/10.1109/jmems.2020.3000392
Autor:
William E. Bentley, David N. Quan, Reza Ghodssi, Pradeep Ramiah Rajasekaran, Liangbing Hu, Ashley A. Chapin, Jens Herberholz
Publikováno v:
Microsystems & Nanoengineering, Vol 6, Iss 1, Pp 1-13 (2020)
Gut–brain axis (GBA) communication relies on serotonin (5-HT) signaling between the gut epithelium and the peripheral nervous system, where 5-HT release patterns from the basolateral (i.e., bottom) side of the epithelium activate nerve afferents. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6216d872e750a3499a36e17c652b38a7
http://link.springer.com/article/10.1038/s41378-020-00184-4
http://link.springer.com/article/10.1038/s41378-020-00184-4
Autor:
Ashley A. Chapin, Robert Ohlendorf, Agata Wiśniowska, Jitendra Sharma, Alan Jasanoff, Mriganka Sur, Mitul Desai, Adrian L. Slusarczyk
Publikováno v:
eLife, Vol 10 (2021)
eLife
eLife
Molecular imaging could have great utility for detecting, classifying, and guiding treatment of brain disorders, but existing probes offer limited capability for assessing relevant physiological parameters. Here we describe a potent approach for noni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::623be30bcabc8fa7cf360ab9d27e6112
https://elifesciences.org/articles/70237
https://elifesciences.org/articles/70237
Autor:
William E. Bentley, Reza Ghodssi, David N. Quan, Ashley A. Chapin, Pradeep Ramiah Rajasekaran, Jens Herberholz
Publikováno v:
Microsystems & Nanoengineering, Vol 6, Iss 1, Pp 1-12 (2020)
This work presents a 3D-printed, modular, electrochemical sensor-integrated transwell system for monitoring cellular and molecular events in situ without sample extraction or microfluidics-assisted downstream omics. Simple additive manufacturing tech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23fd2a0b2e018810cb210feb764d1939
https://doi.org/10.1038/s41378-020-00208-z
https://doi.org/10.1038/s41378-020-00208-z
Autor:
Justin M. Stine, Reza Ghodssi, Sanwei Liu, George E. Banis, Luke A. Beardslee, Pankaj J. Pasricha, Sangwook Chu, Ashley A. Chapin
Publikováno v:
ACS sensors. 5(4)
Ingestible electronic systems that are capable of embedded sensing, particularly within the gastrointestinal (GI) tract and its accessory organs, have the potential to screen for diseases that are difficult if not impossible to detect at an early sta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e832a9a9e1c6b88735bef3d18f88530
https://pubmed.ncbi.nlm.nih.gov/32157868
https://pubmed.ncbi.nlm.nih.gov/32157868
Autor:
Jens Herberholz, Ashley A. Chapin, Reza Ghodssi, Pradeep Ramiah Rajasekaran, William E. Bentley
Publikováno v:
2019 20th International Conference on Solid-State Sensors, Actuators and Microsystems & Eurosensors XXXIII (TRANSDUCERS & EUROSENSORS XXXIII).
This work presents a new porous membrane-based approach towards designing biosensors for in vitro bio microsystems. Compared to standard microfluidic sensor systems, cell molecular release can be more directly measured by interfacial sensors fabricat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b10585a2f6a0301a908ca56137bbe0f
https://doi.org/10.1109/transducers.2019.8808615
https://doi.org/10.1109/transducers.2019.8808615