Zobrazeno 1 - 10
of 1 632
pro vyhledávání: '"Ashley A. Bush"'
Autor:
Liwei Ma, Edwin C. K. Tan, Ashley I. Bush, Colin L. Masters, Benjamin Goudey, Liang Jin, Yijun Pan, AIBL Research Group
Publikováno v:
Journal of Epidemiology and Global Health, Vol 14, Iss 3, Pp 1130-1141 (2024)
Abstract Background The associations between mood disorders (anxiety and depression) and mild cognitive impairment (MCI) or Alzheimer’s dementia (AD) remain unclear. Methods Data from the Australian Imaging, Biomarker & Lifestyle (AIBL) study were
Externí odkaz:
https://doaj.org/article/dd74eadef35446cd963c3f923eed17ec
Autor:
Adityas Purnianto, Celeste Mawal, Mitali M. Kulkarni, Huaqi Su, Tiana F. Koukoulis, Patricia Wongsodirdjo, Ya Hui Hung, Scott Ayton, Ashley I. Bush, Kevin J. Barnham, Laura J. Vella
Publikováno v:
Journal of Extracellular Biology, Vol 3, Iss 10, Pp n/a-n/a (2024)
Abstract Cells have developed a highly regulated system for the uptake, transport, utilization, storage, and export of metals, ensuring the maintenance of cellular homeostasis. Small extracellular vesicles (sEVs) function as a mechanism through which
Externí odkaz:
https://doaj.org/article/354283fce5264150957df1fa668a3d24
Autor:
James B. W. Hilton, Kai Kysenius, Jeffrey R. Liddell, Stephen W. Mercer, Bence Paul, Joseph S. Beckman, Catriona A. McLean, Anthony R. White, Paul S. Donnelly, Ashley I. Bush, Dominic J. Hare, Blaine R. Roberts, Peter J. Crouch
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract The copper compound CuII(atsm) has progressed to phase 2/3 testing for treatment of the neurodegenerative disease amyotrophic lateral sclerosis (ALS). CuII(atsm) is neuroprotective in mutant SOD1 mouse models of ALS where its activity is asc
Externí odkaz:
https://doaj.org/article/236516f7a4ca40819c0aeb1e8d9cbdfc
Autor:
Jeffrey R. Liddell, James B. W. Hilton, Kai Kysenius, Jessica L. Billings, Sara Nikseresht, Lachlan E. McInnes, Dominic J. Hare, Bence Paul, Stephen W. Mercer, Abdel A. Belaidi, Scott Ayton, Blaine R. Roberts, Joseph S. Beckman, Catriona A. McLean, Anthony R. White, Paul S. Donnelly, Ashley I. Bush, Peter J. Crouch
Publikováno v:
Molecular Neurodegeneration, Vol 19, Iss 1, Pp 1-21 (2024)
Abstract Background Ferroptosis is a form of regulated cell death characterised by lipid peroxidation as the terminal endpoint and a requirement for iron. Although it protects against cancer and infection, ferroptosis is also implicated in causing ne
Externí odkaz:
https://doaj.org/article/c1c1ef71cd304efcb8d9a959888a9cd7
Autor:
Parsa Ravanfar, R. Jarrett Rushmore, Amanda E. Lyall, Vanessa Cropley, Nikos Makris, Patricia Desmond, Dennis Velakoulis, Martha E. Shenton, Ashley I. Bush, Susan L. Rossell, Christos Pantelis, Warda T. Syeda, Andrea Phillipou
Publikováno v:
Journal of Eating Disorders, Vol 11, Iss 1, Pp 1-10 (2023)
Abstract Background Anorexia nervosa (AN) is a potentially fatal psychiatric condition, associated with structural brain changes such as gray matter volume loss. The pathophysiological mechanisms for these changes are not yet fully understood. Iron i
Externí odkaz:
https://doaj.org/article/5c4a69269c7e4078afef15e0eb282b06
Autor:
Janelle L. Hancock, Murugan Kalimutho, Jasmin Straube, Malcolm Lim, Irma Gresshoff, Jodi M. Saunus, Jason S. Lee, Sunil R. Lakhani, Kaylene J. Simpson, Ashley I. Bush, Robin L. Anderson, Kum Kum Khanna
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-16 (2023)
Abstract Background Despite overall improvement in breast cancer patient outcomes from earlier diagnosis and personalised treatment approaches, some patients continue to experience recurrence and incurable metastases. It is therefore imperative to un
Externí odkaz:
https://doaj.org/article/d9fe64d800bf4622bdc3d1e38364ba23
Publikováno v:
Digital Communications and Networks, Vol 9, Iss 1, Pp 223-235 (2023)
Situated at the intersection of technology and medicine, the Internet of Things (IoT) holds the promise of addressing some of healthcare's most pressing challenges, from medical error, to chronic drug shortages, to overburdened hospital systems, to d
Externí odkaz:
https://doaj.org/article/daa26186fdaf45749a585340647c25c1
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 164, Iss , Pp 114930- (2023)
Vitamin A (retinol) is a lipid-soluble vitamin that acts as a precursor for several bioactive compounds, such as retinaldehyde (retinal) and isomers of retinoic acid. Retinol and all-trans-retinoic acid (atRA) penetrate the blood-brain barrier and ar
Externí odkaz:
https://doaj.org/article/406d3a0553294d89b96cafc69c4db103
Autor:
Francesca M. Alves, Kai Kysenius, Marissa K. Caldow, Justin P. Hardee, Jin D. Chung, Jennifer Trieu, Dominic J. Hare, Peter J. Crouch, Scott Ayton, Ashley I. Bush, Gordon S. Lynch, René Koopman
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 13, Iss 3, Pp 1541-1553 (2022)
Abstract Background Oxidative stress is implicated in the pathophysiology of Duchenne muscular dystrophy (DMD, caused by mutations in the dystrophin gene), which is the most common and severe of the muscular dystrophies. To our knowledge, the distrib
Externí odkaz:
https://doaj.org/article/da04fde3e0e44d6e87bd46e1112410fb
Autor:
Gemma Cadby, Corey Giles, Phillip E. Melton, Kevin Huynh, Natalie A. Mellett, Thy Duong, Anh Nguyen, Michelle Cinel, Alex Smith, Gavriel Olshansky, Tingting Wang, Marta Brozynska, Mike Inouye, Nina S. McCarthy, Amir Ariff, Joseph Hung, Jennie Hui, John Beilby, Marie-Pierre Dubé, Gerald F. Watts, Sonia Shah, Naomi R. Wray, Wei Ling Florence Lim, Pratishtha Chatterjee, Ian Martins, Simon M. Laws, Tenielle Porter, Michael Vacher, Ashley I. Bush, Christopher C. Rowe, Victor L. Villemagne, David Ames, Colin L. Masters, Kevin Taddei, Matthias Arnold, Gabi Kastenmüller, Kwangsik Nho, Andrew J. Saykin, Xianlin Han, Rima Kaddurah-Daouk, Ralph N. Martins, John Blangero, Peter J. Meikle, Eric K. Moses
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Dysregulation of lipid metabolism is associated with coronary artery disease (CAD). Here, the authors perform GWAS of the serum lipidome to identify variants associated with lipid species that are putatively in the mechanistic pathway to CAD.
Externí odkaz:
https://doaj.org/article/1160229aa3d04cc8a6b15b682b0f47a7