Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Ashley A George"'
Autor:
Ashley A George, Sara Hayden, Lars C Holzhausen, Eva Y Ma, Sachihiro C Suzuki, Susan E Brockerhoff
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e84394 (2014)
Highly polarized cells such as photoreceptors require precise and efficient strategies for establishing and maintaining the proper subcellular distribution of proteins. The signals and molecular machinery that regulate trafficking and sorting of syna
Externí odkaz:
https://doaj.org/article/23b32bad8b6647ec833c44fa0724b42b
Autor:
Tongcui Ma, Matthew McGregor, Leila Giron, Guorui Xie, Ashley F George, Mohamed Abdel-Mohsen, Nadia R Roan
Publikováno v:
eLife, Vol 11 (2022)
High-parameter single-cell phenotyping has enabled in-depth classification and interrogation of immune cells, but to date has not allowed for glycan characterization. Here, we develop CyTOF-Lec as an approach to simultaneously characterize many prote
Externí odkaz:
https://doaj.org/article/11ad9b2293b548ec8928b0045a349672
Autor:
Opeyemi S Adeniji, Leticia Kuri-Cervantes, Chenfei Yu, Ziyang Xu, Michelle Ho, Glen M Chew, Cecilia Shikuma, Costin Tomescu, Ashley F George, Nadia R Roan, Lishomwa C Ndhlovu, Qin Liu, Kar Muthumani, David B Weiner, Michael R Betts, Han Xiao, Mohamed Abdel-Mohsen
Publikováno v:
PLoS Pathogens, Vol 17, Iss 11, p e1010034 (2021)
Siglec-9 is an MHC-independent inhibitory receptor expressed on a subset of natural killer (NK) cells. Siglec-9 restrains NK cytotoxicity by binding to sialoglycans (sialic acid-containing glycans) on target cells. Despite the importance of Siglec-9
Externí odkaz:
https://doaj.org/article/7893d0635c944c17b3235ba1b247de02
Autor:
Ashley F. George, Matthew McGregor, David Gingrich, Jason Neidleman, Rebecca S. Marquez, Kyrlia C. Young, Kaavya L. Thanigaivelan, Warner C. Greene, Phyllis C. Tien, Amelia N. Deitchman, Trimble L. Spitzer, Nadia R. Roan
Publikováno v:
Viruses, Vol 14, Iss 8, p 1723 (2022)
The efficacy of HIV pre-exposure prophylaxis (PrEP) is high in men who have sex with men, but much more variable in women, in a manner largely attributed to low adherence. This reduced efficacy, however, could also reflect biological factors. Transmi
Externí odkaz:
https://doaj.org/article/f55403f065a443fe8877ab39b32d77fa
Autor:
Ashley F. George, Nadia R. Roan
Publikováno v:
Current HIV/AIDS Reports. 20:76-85
Purpose of Review This review describes how advances in CyTOF and high-dimensional analysis methods have furthered our understanding of HIV transmission, pathogenesis, persistence, and immunity. Recent Findings CyTOF has generated important insight o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b53b9dc2e298d9735693cf469e3102f5
https://doi.org/10.1007/s11904-023-00649-x
https://doi.org/10.1007/s11904-023-00649-x
Autor:
Jason Neidleman, Xiaoyu Luo, Julie Frouard, Guorui Xie, Gurjot Gill, Ellen S. Stein, Matthew McGregor, Tongcui Ma, Ashley F. George, Astrid Kosters, Warner C. Greene, Joshua Vasquez, Eliver Ghosn, Sulggi Lee, Nadia R. Roan
Publikováno v:
Cell Reports Medicine, Vol 1, Iss 6, Pp 100081- (2020)
Summary: Convalescing coronavirus disease 2019 (COVID-19) patients mount robust T cell responses against SARS-CoV-2, suggesting an important role of T cells in viral clearance. To date, the phenotypes of SARS-CoV-2-specific T cells remain poorly defi
Externí odkaz:
https://doaj.org/article/a72f1c6b4feb4f37be67cf2c5c77d4e5
Autor:
Tongcui Ma, Xiaoyu Luo, Ashley F George, Gourab Mukherjee, Nandini Sen, Trimble L Spitzer, Linda C Giudice, Warner C Greene, Nadia R Roan
Publikováno v:
eLife, Vol 9 (2020)
The female reproductive tract (FRT) is the most common site of infection during HIV transmission to women, but viral remodeling complicates characterization of cells targeted for infection. Here, we report extensive phenotypic analyses of HIV-infecte
Externí odkaz:
https://doaj.org/article/e2465c199afb47b69b954f976129fd78
Autor:
Rahul K. Suryawanshi, Irene P. Chen, Tongcui Ma, Abdullah M. Syed, Noah Brazer, Prachi Saldhi, Camille R. Simoneau, Alison Ciling, Mir M. Khalid, Bharath Sreekumar, Pei-Yi Chen, G. Renuka Kumar, Mauricio Montano, Ronne Gascon, Chia-Lin Tsou, Miguel A. Garcia-Knight, Alicia Sotomayor-Gonzalez, Venice Servellita, Amelia Gliwa, Jenny Nguyen, Ines Silva, Bilal Milbes, Noah Kojima, Victoria Hess, Maria Shacreaw, Lauren Lopez, Matthew Brobeck, Fred Turner, Frank W. Soveg, Ashley F. George, Xiaohui Fang, Mazharul Maishan, Michael Matthay, Mary Kate Morris, Debra Wadford, Carl Hanson, Warner C. Greene, Raul Andino, Lee Spraggon, Nadia R. Roan, Charles Y. Chiu, Jennifer A. Doudna, Melanie Ott
Publikováno v:
Nature, vol 607, iss 7918
SARS-CoV-2 Delta and Omicron are globally relevant variants of concern. Although individuals infected with Delta are at risk of developing severe lung disease, infection with Omicron often causes milder symptoms, especially in vaccinated individuals1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a457aae7118cf5f209aea878cc86dd9
https://doi.org/10.1038/s41586-022-04865-0
https://doi.org/10.1038/s41586-022-04865-0
Publikováno v:
Journal of colloid and interface science. 631
Niosomes are vesicular carriers formed by a bilayer shell, which is composed of non-ionic surfactants with the addition of a structural supporting agent. Cholesterol is typically used as an additive to increase the stability or drug entrapment effici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecf7295f948fa999f88409294a41e7a8
https://pubmed.ncbi.nlm.nih.gov/36379113
https://pubmed.ncbi.nlm.nih.gov/36379113
