Výsledky vyhledávání - "Ashley, Stueck"

Akademický článek

The Hydroxypyridinone Iron Chelator DIBI Reduces Bacterial Load and Inflammation in Experimental Lung Infection

Autor: Xiyang Zhang, Rhea Nickerson, Lauren Burton, Ashley Stueck, Bruce Holbein, Zhenyu Cheng, Juan Zhou, Christian Lehmann

Publikováno v: Biomedicines, Vol 12, Iss 7, p 1452 (2024)

Iron plays a critical role in lung infections due to its function in the inflammatory immune response but also as an important factor for bacterial growth. Iron chelation represents a potential therapeutic approach to inhibit bacterial growth and pat

Externí odkaz: https://doaj.org/article/b381a2906c89420fb249b1df8dac0e9f

Zobrazit plný text záznamu

Akademický článek

Alveolar macrophage metabolic programming via a C-type lectin receptor protects against lipo-toxicity and cell death

Autor: Michal Scur, Ahmad Bakur Mahmoud, Sayanti Dey, Farah Abdalbarri, Iona Stylianides, Daniel Medina-Luna, Gayani S. Gamage, Aaron Woblistin, Alexa N. M. Wilson, Haggag S. Zein, Ashley Stueck, Andrew Wight, Oscar A. Aguilar, Francesca Di Cara, Brendon D. Parsons, Mir Munir A. Rahim, James R. Carlyle, Andrew P. Makrigiannis

Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)

Alveolar macrophages (AM) in the lungs maintain surfactant during homeostasis and respond to infectious pathogens. Here the authors show that in the absence of NKR-P1B, pneumococcal infection is more severe because KO AM have increased rates of lipid

Externí odkaz: https://doaj.org/article/ca6a2921570140329609abd0d7a69abd

Zobrazit plný text záznamu

Akademický článek

Intratumoral heterogeneity and clonal evolution in liver cancer

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)

Immune-mediated selection pressures impact the clonal evolution of tumours. Here, in hepatocellular carcinoma the authors map spatio-temporal interactions between tumor and immune cells, highlighting the regulatory substrate of intra-tumoural heterog

Externí odkaz: https://doaj.org/article/b7e9387e6d0443a18b41f98ca9cd0d20

Zobrazit plný text záznamu

Akademický článek

Feasibility and reproducibility of liver surface nodularity quantification for the assessment of liver cirrhosis using CT and MRI

Autor: Grace C. Lo, Cecilia Besa, Michael J. King, Martin Kang, Ashley Stueck, Swan Thung, Mathilde Wagner, Andrew D. Smith, Bachir Taouli

Publikováno v: European Journal of Radiology Open, Vol 4, Iss , Pp 95-100 (2017)

Purpose: To assess intra-observer, inter-observer and inter-modality (CT vs. MRI) reproducibility of liver surface nodularity (LSN) scores measured with software used for detection of liver fibrosis. Methods: This IRB-approved retrospective study inc

Externí odkaz: https://doaj.org/article/a6fbfacc2e5f47ac894d08ab3010424b

Zobrazit plný text záznamu

Gastrointestinal stromal tumors caused by novel germline variants in SDHB and KIT: a report of two cases and literature review

Autor: Sean Rasmussen, Ashley Stueck, Bruce Colwell, Daniel Gaston, Michael Carter

Publikováno v: Clinical Journal of Gastroenterology. 15:869-875

Gastrointestinal stromal tumors (GISTs) are usually caused by somatic mutations, but there are rare germline variants that predispose patients to the development of one or, more commonly, multiple GISTs. We present 2 cases of multifocal GISTs related

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8abb67eb72c58731ffc9108c028c2487
https://doi.org/10.1007/s12328-022-01672-y

Zobrazit plný text záznamu

Prospective Evaluation of Virtual MR Elastography With Diffusion‐Weighted Imaging in Subjects With Nonalcoholic Fatty Liver Disease

Autor: Elyisha Hanniman, Andreu F. Costa, Chris V. Bowen, Mohamed Abdolell, Ashley Stueck, Magnus McLeod, Kevork Peltekian, James Rioux, Sharon E. Clarke

Publikováno v: Journal of Magnetic Resonance Imaging. 56:1448-1456

Non-alcoholic fatty liver disease (NAFLD) is increasingly common worldwide and can lead to the development of cirrhosis, liver failure and cancer. Virtual magnetic resonance elastography (VMRE), which is based on a shifted apparent diffusion coeffici

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3bd8267162baf4e7a8794610268db80
https://doi.org/10.1002/jmri.28154

Zobrazit plný text záznamu

Akademický článek

Iron Chelation in Murine Models of Systemic Inflammation Induced by Gram-Positive and Gram-Negative Toxins

Autor: Danielle Fokam, Kayle Dickson, Kiyana Kamali, Bruce Holbein, Patricia Colp, Ashley Stueck, Juan Zhou, Christian Lehmann

Publikováno v: Antibiotics, Vol 9, Iss 6, p 283 (2020)

Iron is an essential element for various physiological processes, but its levels must remain tightly regulated to avoid cellular damage. Similarly, iron plays a dual role in systemic inflammation, such as with sepsis. Leukocytes utilize iron to produ

Externí odkaz: https://doaj.org/article/12cae45798ee41c2a22eb1848d7490a0

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání