Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Ashlesha Chauhan"'
Publikováno v:
Results in Chemistry, Vol 11, Iss , Pp 101799- (2024)
Sotorasib is a small molecule inhibitor and approved by USFDA for the treatment of non-small cell lung cancer (NSCLC). In the present study, forced degradation behavior of sotorasib was carried out by utilizing LC-MS/MS technique. As per ICH guidelin
Externí odkaz:
https://doaj.org/article/c3700359cad242d2aa10ea514a87e7ed
Publikováno v:
Results in Chemistry, Vol 7, Iss , Pp 101465- (2024)
The main objective of this study is to develop and validate an LC-MS/MS stability-indicating method for the isolation, identification, and characterization of forced degradation products of mobocertinib under various stress conditions, utilizing LC-M
Externí odkaz:
https://doaj.org/article/7e10dedbbf1340df8f90374bc7768e5b
Autor:
Jeeva Geogin, Madhuri Patel, Nishith Teraiya, Ashlesha Chauhan, Priti Trivedi, Binit Patel, Samir Patel, Archita Patel
Publikováno v:
Luminescence.
Publikováno v:
Anti-Cancer Agents in Medicinal Chemistry. 22:2142-2155
Background: Hexahydroquinoline as a small molecule was reported for good cytotoxicity and affinity towards Mcl-1. Hence, new compounds were explored as Mcl-1 inhibitors to be potent anticancer agents. Objective: Compounds were synthesized and screene