Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Ashleigh S. Hanner"'
Publikováno v:
Journal of Biological Chemistry. 294:17131-17142
The polyamines putrescine, spermidine, and spermine are required for normal eukaryotic cellular functions. However, the minimum requirement for polyamines varies widely, ranging from very high concentrations (mm) in mammalian cells to extremely low i
Autor:
Myung Hee Park, Danielle A. Springer, Raghavendra G. Mirmira, Rajesh Kumar Kar, Teresa L. Mastracci, Matthew F. Starost, Ashleigh S. Hanner
Eukaryotic initiation factor 5A (eIF5A) is an essential factor with a unique amino acid, hypusine, required for its activity. Hypusine is formed exclusively in eIF5A by a post-translational modification involving two enzymes, deoxyhypusine synthase (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b366acb1eaa254f4d0251f7858d994dd
https://doi.org/10.1101/2021.05.11.443636
https://doi.org/10.1101/2021.05.11.443636
Autor:
Raghavendra G. Mirmira, Ashleigh S. Hanner, Myung Hee Park, Danielle A. Springer, Matthew F. Starost, Rajesh Kumar Kar, Teresa L. Mastracci
Publikováno v:
The Journal of Biological Chemistry
Eukaryotic initiation factor 5A (eIF5A) is an essential protein that requires a unique amino acid, hypusine, for its activity. Hypusine is formed exclusively in eIF5A post-translationally via two enzymes, deoxyhypusine synthase (DHPS) and deoxyhypusi
Autor:
Ashleigh S, Hanner, Matthew, Dunworth, Robert A, Casero, Colin W, MacDiarmid, Myung Hee, Park
Publikováno v:
J Biol Chem
The polyamines putrescine, spermidine, and spermine are required for normal eukaryotic cellular functions. However, the minimum requirement for polyamines varies widely, ranging from very high concentrations (mm) in mammalian cells to extremely low i
Autor:
Ping Yee Billie Au, Marie T. McDonald, Myung Hee Park, Ashleigh S. Hanner, Julia Tagoe, Mythily Ganapathi, Rebecca Willaert, Wendy K. Chung, Jiayao Wang, Liyong Deng, Barry Wolf, Richard E. Person, Joanna Lee, Leah R. Padgett, Yufeng Shen, Charles A. LeDuc, Kentaro Yamada, Orrin Devinsky, Volkan Okur, Raghavendra G. Mirmira, Teresa L. Mastracci, Danielle Karlowicz
Hypusine is formed post-translationally from lysine and is found in a single cellular protein, eukaryotic translation initiation factor-5A (eIF5A), and its homolog eIF5A2. Biosynthesis of hypusine is a two-step reaction involving the enzymes deoxyhyp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbd884b5a92a0de7b675b22d6e13b7c9
https://europepmc.org/articles/PMC6369575/
https://europepmc.org/articles/PMC6369575/
Autor:
Laura N. Rusche, Ashleigh S. Hanner
Publikováno v:
Genetics. 207(2)
A key unresolved issue in molecular evolution is how paralogs diverge after gene duplication. For multifunctional genes, duplication is often followed by subfunctionalization. Subsequently, new or optimized molecular properties may evolve once the pr
Autor:
Ashleigh S. Hanner, Shivali Kapoor, Kristen M. Humphrey, Laura N. Rusche, Justin M. H. Heltzel, Christopher B. Rupert
Publikováno v:
Epigenetics: Current Research and Emerging Trends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c7fb3e7657719ff5e2167c30ebd58d7
https://doi.org/10.21775/9781910190074.03
https://doi.org/10.21775/9781910190074.03