Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Ashleigh N. Riegler"'
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-13 (2023)
Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes severe lower airway disease and death in a subset of patients. Knowledge on the relative contribution of programmed cell death (PCD) to lung pathology is limited to few huma
Externí odkaz:
https://doaj.org/article/12cc4a7e32d04e41b53bd21801cb8704
Autor:
Terry Brissac, Eriel Martínez, Katherine L. Kruckow, Ashleigh N. Riegler, Feroze Ganaie, Hansol Im, Sayan Bakshi, Nicole M. Arroyo-Diaz, Brady L. Spencer, Jamil S. Saad, Moon H. Nahm, Carlos J. Orihuela
Publikováno v:
mBio, Vol 12, Iss 5 (2021)
Streptococcus pneumoniaeSpnSpn
Externí odkaz:
https://doaj.org/article/9ce4442b4bb54ebd8049a3b39250c14b
Autor:
Sang-Sang Park, Norberto Gonzalez-Juarbe, Ashleigh N. Riegler, Hansol Im, Yvette Hale, Maryann P. Platt, Christina Croney, David E. Briles, Carlos J. Orihuela
Publikováno v:
Cell Reports, Vol 35, Iss 11, Pp 109267- (2021)
Summary: Streptococcus pneumoniae (Spn) alone and during co-infection with influenza A virus (IAV) can result in severe pneumonia with mortality. Pneumococcal surface protein A (PspA) is an established virulence factor required for Spn evasion of lac
Externí odkaz:
https://doaj.org/article/3747f4cbc1c44c48a679527ec403ada2
Autor:
Norberto Gonzalez-Juarbe, Ashleigh N. Riegler, Alexander S. Jureka, Ryan P. Gilley, Jeffrey D. Brand, John E. Trombley, Ninecia R. Scott, Maryann P. Platt, Peter H. Dube, Chad M. Petit, Kevin S. Harrod, Carlos J. Orihuela
Publikováno v:
Cell Reports, Vol 32, Iss 8, Pp 108062- (2020)
Summary: Pneumonias caused by influenza A virus (IAV) co- and secondary bacterial infections are characterized by their severity and high mortality rate. Previously, we have shown that bacterial pore-forming toxin (PFT)-mediated necroptosis is a key
Externí odkaz:
https://doaj.org/article/b804d5f73aa147ecb872b34cc558199e
Publikováno v:
Pathogens, Vol 8, Iss 4, p 203 (2019)
Pneumococcal vaccine development is driven by the achievement of high activity in a single gatekeeper assay: the bacterial opsonophagocytic killing (OPK) assay. New evidence challenges the dogma that anti-capsular antibodies have only a single functi
Externí odkaz:
https://doaj.org/article/9f6ef0eae28a4d00aac63093f9b4d658
Publikováno v:
Clinics in Laboratory Medicine. 43:189-207
Autor:
Adonis D'Mello, Carlos J. Orihuela, Hervé Tettelin, Sarah M. Beno, Ashleigh N. Riegler, Eriel Martínez, Tiffany Davia Ricketts, Ellen F. Foxman
Publikováno v:
Proceedings of the National Academy of Sciences. 117:33507-33518
Streptococcus pneumoniae (Spn) colonizes the nasopharynx and can cause pneumonia. From the lungs it spreads to the bloodstream and causes organ damage. We characterized the in vivo Spn and mouse transcriptomes within the nasopharynx, lungs, blood, he
Autor:
Carlos J. Orihuela, Eriel Martínez, Moon H. Nahm, Hansol Im, Jennifer N Luck, Feroze Ganaie, Jamil S. Saad, Hervé Tettelin, Katherine L Kruckow, Ashleigh N. Riegler, Xiuhong Song, Adonis D'Mello, Elie Ghanem, Kyle H. Cichos
Publikováno v:
Infect Immun
Streptococcus pneumoniae colonizes the nasopharynx asymptomatically but can also cause severe life-threatening disease. Importantly, stark differences in carbohydrate availability exist between the nasopharynx and invasive disease sites, such as the
Autor:
Ashleigh N. Riegler, Katherine L Kruckow, Nicole M Arroyo-Diaz, Brady L Spencer, Sayan Bakshi, Carlos J. Orihuela, Eriel Martínez, Moon H. Nahm, Feroze Ganaie, Hansol Im, Jamil S Saad, Terry Brissac
Publikováno v:
mBio
mBio, Vol 12, Iss 5 (2021)
mBio, Vol 12, Iss 5 (2021)
The polysaccharide capsule that surrounds Streptococcus pneumoniae (Spn) is one of its most important virulence determinants, serving to protect against phagocytosis. To date, 100 biochemical and antigenically distinct capsule types, i.e., serotypes,
Autor:
Yvette Hale, Sang-Sang Park, Carlos J. Orihuela, Norberto Gonzalez-Juarbe, Ashleigh N. Riegler, Christina M. Croney, Maryann P. Platt, Hansol Im, David E. Briles
Publikováno v:
Cell Reports, Vol 35, Iss 11, Pp 109267-(2021)
Cell reports
Cell reports
SUMMARY Streptococcus pneumoniae (Spn) alone and during co-infection with influenza A virus (IAV) can result in severe pneumonia with mortality. Pneumococcal surface protein A (PspA) is an established virulence factor required for Spn evasion of lact