Genetic variation within the Mx gene of commercially selected chicken lines reveals multiple haplotypes, recombination and a protein under selection pressure.

Autor: Janet E Fulton, Jesus Arango, Rizwana A Ali, Elaine B Bohorquez, Ashlee R Lund, Chris M Ashwell, Petek Settar, Neil P O'Sullivan, Matthew D Koci

Publikováno v: PLoS ONE, Vol 9, Iss 9, p e108054 (2014)

The Mx protein is one of the best-characterized interferon-stimulated antiviral mediators. Mx homologs have been identified in most vertebrates examined; however, their location within the cell, their level of activity, and the viruses they inhibit v

Externí odkaz: https://doaj.org/article/64c39aa8bf9047e790c793204af4a766

The Chicken A and E Blood Systems Arise from Genetic Variation in and around the Regulators of Complement Activation Region

Autor: Janet E. Fulton, Wiola Drobik-Czwarno, Anna Wolc, Amy M. McCarron, Ashlee R. Lund, Carl J. Schmidt, Robert L. Taylor

Publikováno v: The Journal of Immunology. 209:1128-1137

The tightly linked A and E blood alloantigen systems are 2 of 13 blood systems identified in chickens. Reported herein are studies showing that the genes encoding A and E alloantigens map within or near to the chicken regulator of complement activati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65899b8e454a7cb735846fa5923d3d70
https://doi.org/10.4049/jimmunol.2101010

Identification and characterisation of endogenous Avian Leukosis Virus subgroup E (ALVE) insertions in chicken whole genome sequencing data

Autor: Andrew S. Mason, David W. Burt, Janet E. Fulton, Paul Hocking, Ashlee R. Lund

Publikováno v: Mobile DNA
Mobile DNA, Vol 11, Iss 1, Pp 1-13 (2020)
Mason, A S, Lund, A R, Hocking, P M, Fulton, J E & Burt, D W 2020, ' Identification and characterisation of endogenous Avian Leukosis Virus subgroup E (ALVE) insertions in chicken whole genome sequencing data ', Mobile DNA, vol. 11, pp. 22 . https://doi.org/10.1186/s13100-020-00216-w

Background Endogenous retroviruses (ERVs) are the remnants of retroviral infections which can elicit prolonged genomic and immunological stress on their host organism. In chickens, endogenous Avian Leukosis Virus subgroup E (ALVE) expression has been

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce09b9e157fdd8a3df38b33b3b481c2b
https://doi.org/10.1186/s13100-020-00216-w

MHC variability in heritage breeds of chickens

Autor: Henry L. Classen, C. Utterbach, K. N. Pinegar, Samuel E. Aggrey, D. R. Korver, Janet E. Fulton, Nicholas B. Anthony, Ashlee R. Lund, Mark E. Berres, Amy M. McCarron

Publikováno v: Poultry Science. 95:393-399

The chicken Major Histocompatibility Complex (MHC) is very strongly associated with disease resistance and thus is a very important region of the chicken genome. Historically, MHC (B locus) has been identified by the use of serology with haplotype sp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbdf9af27bd2551bf4045e606d7bbfaa
https://doi.org/10.3382/ps/pev363

Genetic variation within the Mx gene of commercially selected chicken lines reveals multiple haplotypes, recombination and a protein under selection pressure

Autor: Elaine B. Bohorquez, Petek Settar, Neil P. O'Sullivan, Matthew D. Koci, Christopher M. Ashwell, Janet E. Fulton, Rizwana Ali, Jesus Arango, Ashlee R. Lund

Publikováno v: PLoS ONE
PLoS ONE, Vol 9, Iss 9, p e108054 (2014)

The Mx protein is one of the best-characterized interferon-stimulated antiviral mediators. Mx homologs have been identified in most vertebrates examined; however, their location within the cell, their level of activity, and the viruses they inhibit v

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69f5de25d6fa96b4aa36e6feb28a1757
https://pubmed.ncbi.nlm.nih.gov/25244433