Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Ashlan J. Kunz Coyne"'
Autor:
Ashlan J. Kunz Coyne, Kyle Stamper, Callan Bleick, Razieh Kebriaei, Susan M. Lehman, Michael J. Rybak
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 4 (2024)
ABSTRACTMethicillin-resistant Staphylococcus aureus (MRSA) causes biofilm-related medical device infections. Phage-antibiotic combinations offer potential therapy due to proven in vitro antibiofilm efficacy. We evaluated phage-antibiotic synergy agai
Externí odkaz:
https://doaj.org/article/439d3dcf62f84a31af6b4e37edbf0bdc
Autor:
Amer El Ghali, Ashlan J. Kunz Coyne, Kristen Lucas, Molly Tieman, Xhilda Xhemali, Suet-ping Lau, Gabriela Iturralde, Andrew Purdy, Dana J. Holger, Esther Garcia, Michael P. Veve, Michael J. Rybak
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 2 (2024)
ABSTRACTMulti-drug resistant gram-negative bacteria present a significant global health threat. Cefiderocol (CFDC), a siderophore cephalosporin, has shown potential in combating this threat, but with the currently available data, its role in therapy
Externí odkaz:
https://doaj.org/article/dd8cbdc6b5e441c988efa50e6056b091
Autor:
Ashlan J. Kunz Coyne, Sara Alosaimy, Kristen Lucas, Abdalhamid M. Lagnf, Taylor Morrisette, Kyle C. Molina, Alaina DeKerlegand, Melanie Rae Schrack, S. Lena Kang-Birken, Athena L.V. Hobbs, Jazmin Agee, Nicholson B. Perkins, Mark Biagi, Michael Pierce, James Truong, Justin Andrade, Jeannette Bouchard, Tristan Gore, Madeline A. King, Benjamin M. Pullinger, Kimberly C. Claeys, Shelbye Herbin, Reese Cosimi, Serina Tart, Michael P. Veve, Bruce M. Jones, Leonor M. Rojas, Amy K. Feehan, Marco R. Scipione, Jing J. Zhao, Paige Witucki, Michael J. Rybak
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 1 (2024)
ABSTRACT Eravacycline is a synthetic fluorocycline approved by the U.S. Food and Drug Administration in 2018. This study aimed to describe clinical and microbiological outcomes in addition to associated adverse effects of eravacycline used in U.S. ho
Externí odkaz:
https://doaj.org/article/c7670c6ad2ab4a279e5ee3917f0e0369
Autor:
Ashlan J. Kunz Coyne, Kyle Stamper, Amer El Ghali, Razieh Kebriaei, Biswajit Biswas, Melanie Wilson, Michael V. Deschenes, Truc T. Tran, Cesar A. Arias, Michael J. Rybak
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 4 (2023)
ABSTRACT Enterococcus faecium is a difficult-to-treat pathogen with emerging resistance to most clinically available antibiotics. Daptomycin (DAP) is the standard of care, but even high DAP doses (12 mg/kg body weight/day) failed to eradicate some va
Externí odkaz:
https://doaj.org/article/8dfc54dd9eb448adbe3bb0d313b8d146
Autor:
Razieh Kebriaei, Susan M. Lehman, Rahi M. Shah, Kyle C. Stamper, Ashlan J. Kunz Coyne, Dana Holger, Amer El Ghali, Michael J. Rybak
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 3 (2023)
ABSTRACT Phage therapy has gained attention due to the spread of antibiotic-resistant bacteria and narrow pipeline of novel antibiotics. Phage cocktails are hypothesized to slow the overall development of resistance by challenging the bacteria with m
Externí odkaz:
https://doaj.org/article/6af1e70295ec474eb303d2a280649802
Autor:
Nicholas Rebold, Abdalhamid M. Lagnf, Sara Alosaimy, Dana J. Holger, Paige Witucki, Andrew Mannino, Michelle Dierker, Kristen Lucas, Ashlan J. Kunz Coyne, Amer El Ghali, Kaylee E. Caniff, Michael P. Veve, Michael J. Rybak
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 1 (2023)
ABSTRACT The Centers for Disease Control and Prevention (CDC) categorized carbapenem-resistant Enterobacterales (CRE) infections as an “urgent” health care threat requiring public attention and research. Certain patients with CRE infections may b
Externí odkaz:
https://doaj.org/article/bb0cc000590f459e8dd74d0e4f76ae4d
Autor:
Razieh Kebriaei, Katherine L. Lev, Rahi M. Shah, Kyle C. Stamper, Dana J. Holger, Taylor Morrisette, Ashlan J. Kunz Coyne, Susan M. Lehman, Michael J. Rybak
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 2 (2022)
ABSTRACT Bacterial biofilms are difficult to eradicate and can complicate many infections by forming on tissues and medical devices. Phage+antibiotic combinations (PAC) may be more active on biofilms than either type of agent alone, but it is difficu
Externí odkaz:
https://doaj.org/article/bab1b2b597c141a2b32989460475ea46
Autor:
Ashlan J. Kunz Coyne, Anthony M. Casapao, Carmen Isache, James Morales, Yvette S. McCarter, Christopher A. Jankowski
Publikováno v:
Microbiology Spectrum, Vol 9, Iss 2 (2021)
ABSTRACT The objective of this study was to evaluate whether the addition of the Verigene BC-GN molecular rapid diagnostic test to standard antimicrobial stewardship practices (mRDT + ASP) decreased the time to optimal and effective antimicrobial the
Externí odkaz:
https://doaj.org/article/22e678e10c1a418eaabc1206ac5d72b3
Autor:
Ashlan J. Kunz Coyne, Kyle Stamper, Razieh Kebriaei, Dana J. Holger, Amer El Ghali, Taylor Morrisette, Biswajit Biswas, Melanie Wilson, Michael V. Deschenes, Gregory S. Canfield, Breck A. Duerkop, Cesar A. Arias, Michael J. Rybak
Publikováno v:
Antibiotics, Vol 11, Iss 9, p 1175 (2022)
Multidrug-resistant (MDR) Enterococcus faecium is a challenging nosocomial pathogen known to colonize medical device surfaces and form biofilms. Bacterio (phages) may constitute an emerging anti-infective option for refractory, biofilm-mediated infec
Externí odkaz:
https://doaj.org/article/e296d9e2d0124deda1a74cc2f9037bc0
Autor:
Katherine Lev, Ashlan J. Kunz Coyne, Razieh Kebriaei, Taylor Morrisette, Kyle Stamper, Dana J. Holger, Gregory S. Canfield, Breck A. Duerkop, Cesar A. Arias, Michael J. Rybak
Publikováno v:
Antibiotics, Vol 11, Iss 3, p 392 (2022)
Multidrug-resistant (MDR) Enterococcus faecium is a challenging pathogen known to cause biofilm-mediated infections with limited effective therapeutic options. Lytic bacteriophages target, infect, and lyse specific bacterial cells and have anti-biofi
Externí odkaz:
https://doaj.org/article/903e9a18b43446d6b4a4ec5870cb0385