Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Ashish Tandon"'
Autor:
Ashish Tandon, Ajay Sharma, Jason T Rodier, Alexander M Klibanov, Frank G Rieger, Rajiv R Mohan
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66434 (2013)
This study examined the effects of BMP7 gene transfer on corneal wound healing and fibrosis inhibition in vivo using a rabbit model. Corneal haze in rabbits was produced with the excimer laser performing -9 diopters photorefractive keratectomy. BMP7
Externí odkaz:
https://doaj.org/article/868ca0f35ca4470b9e235b64308db20e
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e82159 (2013)
With their location in the perisinusoidal space of Disse, hepatic stellate cells (HSCs) communicate with all of the liver cell types both by physical association (cell body as well as cytosolic processes penetrating into sinusoids through the endothe
Externí odkaz:
https://doaj.org/article/fcbc5a917f67450490aefbc17ed74f11
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18771 (2011)
Untargeted and uncontrolled gene delivery is a major cause of gene therapy failure. This study aimed to define efficient and safe tissue-selective targeted gene therapy approaches for delivering genes into keratocytes of the cornea in vivo using a no
Externí odkaz:
https://doaj.org/article/2ef7b76fbe4944e39639800beb7ab4ae
Autor:
Rajiv R Mohan, Jonathan C K Tovey, Ajay Sharma, Gregory S Schultz, John W Cowden, Ashish Tandon
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26432 (2011)
Decorin, small leucine-rich proteoglycan, has been shown to modulate angiogenesis in nonocular tissues. This study tested a hypothesis that tissue-selective targeted decorin gene therapy delivered to the rabbit stroma with adeno-associated virus sero
Externí odkaz:
https://doaj.org/article/410dd9ebf3454d8c84765fe8c623f248
Publikováno v:
2022 22nd National Power Systems Conference (NPSC).
Publikováno v:
The American Journal of Pathology. 187:2008-2019
Concanavalin A (ConA) causes immune cell–mediated liver damage, but the contribution of resident nonparenchymal cells (NPCs) is also evident. Hepatic stellate cells (HSCs) induce hepatic inflammation and immunological reactions; we therefore invest
Publikováno v:
Journal of Cellular Physiology. 231:94-105
Bacterial lipopolysaccharide (LPS)-stimulated hepatic stellate cells (HSCs) produce many cytokines including IFNβ, TNFα, and IL6, strongly inhibit DNA synthesis, but induce apoptosis of a small number of hepatocytes. In vivo administration of LPS (
Autor:
Nuzhat A. Kaushal, Sunita Saxena, Inayat Hussain Sheikh, Deep C. Kaushal, Priyanka Priyadarshi, Ashish Tandon, Shakir Ali, Piyush Dravid
Publikováno v:
Acta Parasitologica. 62
Filarial parasites are complex mixtures of antigenic proteins and characterization of these antigenic molecules is essential to identify the diagnostically important filaria-specific antigens. In the present study, we have fractionated the somatic ex
Publikováno v:
Veterinary Ophthalmology. 18:242-250
Objective To evaluate the safety and efficacy of Pirfenidone (PFD) in the treatment of equine corneal fibrosis using an in vitro model. Methods Healthy donor equine corneas were collected and used to generate primary equine corneal fibroblasts (ECFs)
Autor:
Yuanjing Liu, Rajiv R. Mohan, Ashish Tandon, Daniel J. Gibson, John W. Cowden, Gregory S. Schultz, Ajay Sharma, Jonathan C.K. Tovey, Michael Waggoner
Publikováno v:
Journal of Refractive Surgery. 28:285-290
Approximately 80% of Americans older than 12 years have refractive errors.1 Laser eye surgeries such as photorefractive keratectomy (PRK), LASIK, and laser epithelial keratomileusis are frequently used to correct refractive errors and reduce dependen