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Autor:
Jui Yi Hsu, Hui Ju Tseng, Cheng Chung Yen, Hui Kang Liu, Wei Jan Huang, Kun Chang Wu, Kai Cheng Hsu, Ashish Rao Sathyan, Liang Chieh Chen
Publikováno v:
Journal of Natural Products. 84:1096-1103
Type 2 diabetes mellitus (T2DM) is associated with pancreatic β-cell dysfunction and insulin resistance. Islet amyloid polypeptide (IAPP) aggregation is found to induce islet β-cell death in T2DM patients. Recently, we demonstrated that yakuchinone