Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Ashish Kurundkar"'
Autor:
Ashish Kurundkar, Victor J. Thannickal
Publikováno v:
Redox Biology, Vol 9, Iss C, Pp 67-76 (2016)
Redox signaling and oxidative stress are associated with tissue fibrosis and aging. Aging is recognized as a major risk factor for fibrotic diseases involving multiple organ systems, including that of the lung. A number of oxidant generating enzymes
Externí odkaz:
https://doaj.org/article/fcc66c17e2db4b51a305abddaaead209
Autor:
Huaping Chen, Jing Qu, Xiangwei Huang, Ashish Kurundkar, Lanyan Zhu, Naiheng Yang, Aida Venado, Qiang Ding, Gang Liu, Veena B. Antony, Victor J. Thannickal, Yong Zhou
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Matrix stiffening is a feature of pulmonary fibrosis, and is amplified by lung myofibroblasts. Here the authors find that a6 integrin expression is upregulated on lung myofibroblasts in response to matrix stiffness, and this integrin is required for
Externí odkaz:
https://doaj.org/article/bdcc48b3a1814acd99c91ba73f818aa8
Autor:
Yan Y Sanders, Zongbin Cui, Claude Jourdan Le Saux, Jeffrey C Horowitz, Sunad Rangarajan, Ashish Kurundkar, Veena B Antony, Victor J Thannickal
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0116995 (2015)
Transforming growth factor-β (TGF-β) mediates growth-inhibitory effects on most target cells via activation of the canonical SMAD signaling pathway. This growth-inhibitory activity may be coupled with cellular differentiation. Our studies demonstra
Externí odkaz:
https://doaj.org/article/44551e1bf12d4eeaabc695b426941cc8
Autor:
Sunad Rangarajan, Morgan L. Locy, Diptiman Chanda, Ashish Kurundkar, Deepali Kurundkar, Jennifer L. Larson‐Casey, Pilar Londono, Rushita A. Bagchi, Brian Deskin, Hanan Elajaili, Eva S. Nozik, Jessy S. Deshane, Jaroslaw W. Zmijewski, Oliver Eickelberg, Victor J. Thannickal
Publikováno v:
Aging cell. 21(9)
Mitochondrial dysfunction has been associated with age-related diseases, including idiopathic pulmonary fibrosis (IPF). We provide evidence that implicates chronic elevation of the mitochondrial anion carrier protein, uncoupling protein-2 (UCP2), in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd90b4027dd79cc48834539b7f34121a
https://pubmed.ncbi.nlm.nih.gov/35934931
https://pubmed.ncbi.nlm.nih.gov/35934931
Autor:
Sunad Rangarajan, Victor J. Thannickal, Naomi J. Logsdon, Samuel R. Smith, Ashish Kurundkar, Deepali Kurundkar, Jessy S. Deshane, Jaroslaw W. Zmijewski, Yan Y. Sanders, K.G. Dsouza, Mohammad Rehan, Karen Bernard, Diptiman Chanda
Publikováno v:
Nature aging
Aging is a risk factor for progressive fibrotic disorders involving diverse organ systems, including the lung. Idiopathic pulmonary fibrosis, an age-associated degenerative lung disorder, is characterized by persistence of apoptosis-resistant myofibr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f627c2f0e97d41fe6cd46da83953ef79
https://pubmed.ncbi.nlm.nih.gov/34386777
https://pubmed.ncbi.nlm.nih.gov/34386777
Autor:
Ashish Kurundkar, Tushar Pawar, Hitesh Mahale, Pallavi Saple, Pradeep Deshmukh, Sarang Pedgaonkar, Sapana Thakare, Shriram V. Gosavi, Govind Chaudhari
Publikováno v:
Journal of Family Medicine and Primary Care
Background: Given the high incidence of asymptomatic or subclinical SARS-CoV-2 infection, reported cases likely underestimate the overall prevalence and infectivity of COVID-19. Serological test for IgG can provide a better measure of disease activit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8ab469f5f77cd1f97282ccc328c237c
https://pubmed.ncbi.nlm.nih.gov/34041193
https://pubmed.ncbi.nlm.nih.gov/34041193
Autor:
Mark R. Johnson, Yong Zhou, Karen Bernard, Subramaniam Pennathur, Jaeman Byun, Sufen Yang, Ashish Kurundkar, Morgan L. Locy, Victor J. Thannickal, Jaroslaw W. Zmijewski, Nathaniel B. Bone, Sunad Rangarajan
Publikováno v:
Sci Signal
The oxidation of tyrosine residues to generate o,o'-dityrosine cross-links in extracellular proteins is necessary for the proper function of the extracellular matrix (ECM) in various contexts in invertebrates. Tyrosine oxidation is also required for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c601801b6430573f1e0112b7698a9d68
https://pubmed.ncbi.nlm.nih.gov/32788339
https://pubmed.ncbi.nlm.nih.gov/32788339
Publikováno v:
B64. MECHANISTIC ADVANCES IN LUNG FIBROSIS.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78db6e54fdd074540a157d7bdc5a0fec
https://doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a4039
https://doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a4039
Autor:
Victor J. Thannickal, Mohammad Rehan, Ashish Kurundkar, Diptiman Chanda, Deepali Kurundkar, Jaroslaw W. Zmijewski, K.G. Dsouza, Karen Bernard, Naomi J. Logsdon
Publikováno v:
B20. THERAPEUTICS "2020" IN LUNG DISEASE.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec8892d8b81fe6501fd6df68d5a3d2ba
https://doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a2785
https://doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a2785
Autor:
Anas Bernieh, Mary M. Hitt, Ali G Saad, Chad Blackshear, Akhil Maheshwari, Ashish Kurundkar, Parvesh Mohan Garg, Kristen V. Adams
Publikováno v:
Pediatric research
Infants with advanced necrotizing enterocolitis (NEC) often need surgical resection of necrotic bowel. We hypothesized that incomplete resection of NEC lesions, signified by the detection of necrotic patches in margins of resected bowel loops, result
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ae071703844a7e155a1b4047ce87f55
https://pubmed.ncbi.nlm.nih.gov/32438367
https://pubmed.ncbi.nlm.nih.gov/32438367