Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Ashish G. Soman"'
Publikováno v:
Journal of Liquid Chromatography & Related Technologies. 32:1000-1009
An isocratic reversed phase high performance liquid chromatographic method with charged aerosol detection (CoronaTM CADTM) was developed and validated for the quantitative determination (assay) of 4-methanesulfonyl-piperidine (MSP). This compound has
Autor:
Madhuri Jerfy, Ashish G. Soman
Publikováno v:
Journal of chromatographic science. 52(5)
Soluplus, a graft copolymer of polyethylene glycol, vinyl caprolactam and vinyl acetate, is designed to solubilize poorly soluble active pharmaceutical ingredients. A straightforward aqueous gel permeation chromatography method that exploits both siz
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 76
pH stress testing is an integral part of pharmaceutical stress testing and is a regulatory requirement for validating a stability indicating analytical method and elucidating degradation products and degradation pathways. This paper reports the resul
Autor:
Sara M. Hein, Leonard A. Smith, Vicki A. Montgomery, Ilja V. Khavrutskii, Nisarga L. Phatak, Donald T. Wicklow, Yvette Campbell, John H. Cardellina, Gregory J. Tawa, Xin Hu, Vanessa S. Eccard, Virginia I. Roxas-Duncan, Biren K. Joshi, James B. Gloer, Ashish G. Soman, Ulrich Höller, Anders Wallqvist
Publikováno v:
ACS medicinal chemistry letters. 3(5)
An in silico screen of the NIH Molecular Library Small Molecule Repository (MLSMR) of ∼350000 compounds and confirmatory bioassays led to identification of chaetochromin A (1) as an inhibitor of botulinum neurotoxin serotype A (BoNT A). Subsequent
Publikováno v:
Die Makromolekulare Chemie, Theory and Simulations. 2:711-719
In this work, a neural network was used to learn features in potential energy surfaces and relate those features to conformational properties of a series of polymers. Specifically, we modeled Monte Carlo simulations of 20 polymers in which we calcula
Publikováno v:
Journal of chromatographic science. 47(4)
A reversed-phase high-performance liquid chromatographic method (HPLC) with diode-array detection (DAD) has been evaluated for monitoring trace levels of impurities, such as 4-amino-2-ethoxy-cinnamic acid (impurity A), hydrochloride salt of 4-amino-2
Publikováno v:
Journal of chromatographic science. 46(6)
A reversed-phase high-performance liquid chromatographic method (HPLC) with diode-array detection is developed and validated for the quantitative determination of formaldehyde in a drug substance. Formaldehyde (HCHO) is reacted with 2,4-dinitrophenyl
Publikováno v:
Journal of natural products. 64(2)
Five new phenopicolinic acid analogues (1-5) have been isolated from solid-substrate fermentation cultures of Verticillium lecanii. The most abundant component (vertilecanin A; 1) displays antiinsectan activity against Helicoverpa zea. These compound
Publikováno v:
Journal of natural products. 62(4)
Sporovexins A-C (1-3) and 3'-O-desmethyl-1-epipreussomerin C (4) have been isolated from liquid cultures of the coprophilous fungus Sporormiella vexans (JS 306). The structures of these new metabolites were elucidated on the basis of MS and NMR analy
Antifungal and antibacterial metabolites from a sclerotium-colonizing isolate of Mortierella vinacea
Publikováno v:
Journal of natural products. 62(2)
The known compound methyl 2,4-dihydroxy-3,5,6-trimethylbenzoate (1) and three new related metabolites, which we have named mortivinacins A (2), B (3), and C (4), were identified as metabolites of the fungus Mortierella vinacea. Nicotinic acid (5) was