Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Ashish Anshu"'
Autor:
Hamidullah Khan, Ashish Anshu, Aman Prasad, Sushmita Roy, Justin Jeffery, Wasakorn Kittipongdaja, David T. Yang, Stefan M. Schieke
Publikováno v:
Cell Reports, Vol 29, Iss 10, Pp 3009-3018.e4 (2019)
Summary: Metabolic flexibility allows cells to adapt to various environments and limits the efficacy of metabolic drugs. Therapeutic targeting of cancer metabolism relies on defining limiting requirements and vulnerabilities in the highly dynamic met
Externí odkaz:
https://doaj.org/article/553eb4e3b9a748c286cfdb7fef8f791d
Autor:
Ashish Anshuman, MJ Praseetha, Ambica Rangaiah, G Nagaraju, M Swetha, Shantala Gowdara Basawarajappa
Publikováno v:
Journal of Clinical and Diagnostic Research, Vol 18, Iss 11, Pp 01-05 (2024)
Introduction: Human Adenoviruses (HAdV) have been implicated in a variety of infections, including conjunctivitis, respiratory tract infections, genitourinary infections and gastroenteritis. Epidemic Keratoconjunctivitis (EKC) is a severe ocular surf
Externí odkaz:
https://doaj.org/article/6aed0b7beddc4542ab611cce4184032a
Autor:
Benjamin E. Turk, Jagadeesh Kumar Uppala, Leena Sathe, Chandrima Ghosh, Ashish Anshu, Madhusudan Dey, Charlotte I. Hammond, P. Raj Pokkuluri
Publikováno v:
Sci Signal
During cellular stress in the budding yeast Saccharomyces cerevisiae, an endoplasmic reticulum (ER)-resident dual kinase and RNase Ire1 splices an intron from HAC1 mRNA in the cytosol, thereby releasing its translational block. Hac1 protein then acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::478e9ba3c24ef1d34a28c13ae4fa83ce
https://doi.org/10.1126/scisignal.aaz4401
https://doi.org/10.1126/scisignal.aaz4401
Publikováno v:
Molecular and Cellular Biology. 35:199-210
A signaling network called the unfolded protein response (UPR) resolves the protein-folding defects in the endoplasmic reticulum (ER) from yeasts to humans. In the yeast Saccharomyces cerevisiae, the UPR activation involves (i) aggregation of the ER-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0e975392ecea8f44e4db5b3f524da80
https://doi.org/10.1128/mcb.00981-14
https://doi.org/10.1128/mcb.00981-14
Autor:
Aman Prasad, Wasakorn Kittipongdaja, Hamidullah Khan, Stefan M. Schieke, Ashish Anshu, Justin J. Jeffery, Sushmita Roy, David T. Yang
Publikováno v:
Cell Reports, Vol 29, Iss 10, Pp 3009-3018.e4 (2019)
Cell Rep
Cell Rep
Summary: Metabolic flexibility allows cells to adapt to various environments and limits the efficacy of metabolic drugs. Therapeutic targeting of cancer metabolism relies on defining limiting requirements and vulnerabilities in the highly dynamic met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::206ba11352d7ff500db9fc147361df65
https://doi.org/10.1016/j.celrep.2019.11.007
https://doi.org/10.1016/j.celrep.2019.11.007
Autor:
Sameem Abedin, Scott H. Kaufmann, Ehab Atallah, Aniko Szabo, Ashish Anshu, Karen-Sue B. Carlson, Lyndsey Runaas, Arielle Baim, Alexander Hinman, Laura C. Michaelis, Guru Subramanian Guru Murthy
Publikováno v:
Blood. 134:3837-3837
Background: Outcomes of patients with AML have remained poor despite the availability of cytotoxic chemotherapy, hypomethylating agents (HMAs) and targeted therapies. HMAs, such as azacitidine, in combination with Bcl-2 inhibitors like venetoclax hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17fc434beeb320798e18385ffd28d836
https://doi.org/10.1182/blood-2019-131728
https://doi.org/10.1182/blood-2019-131728
Autor:
Simmy Thomas, Tannya R. Ibarra-Rivera, Puneet Agarwal, Axel H. Schönthal, Michael C. Pirrung, Ashish Anshu
Publikováno v:
Biochemical Pharmacology. 82:600-609
The proteasome has been recognized as a druggable target in cancer cells, and this has led to searches for pharmacologic agents that target this cellular organelle for cancer therapeutic purposes. Syrbactins are a group of microbial metabolites consi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d855b5987f732e100a14588ba54976f
https://doi.org/10.1016/j.bcp.2011.06.031
https://doi.org/10.1016/j.bcp.2011.06.031
Publikováno v:
European Journal of Cancer. 101:S5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::459a79daf7dbec8bafb83c4ffc4cd976
https://doi.org/10.1016/j.ejca.2018.07.154
https://doi.org/10.1016/j.ejca.2018.07.154
Publikováno v:
Cancer Research. 78:2178-2178
Cancer therapies commonly slow rather than cure disease and most patients ultimately relapse. Phenotypic variability and dynamics are a cause for relapsing disease and pose significant challenges to a successful cure. Here we show at the single-cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9021d36da4e9e7fa52b5cc585dd203d
https://doi.org/10.1158/1538-7445.am2018-2178
https://doi.org/10.1158/1538-7445.am2018-2178
Publikováno v:
Journal of Investigative Dermatology. 138:S37
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::653ed3f32b8f58486c69b81a92549c77
https://doi.org/10.1016/j.jid.2018.03.223
https://doi.org/10.1016/j.jid.2018.03.223