Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Ashish, Punia"'
Publikováno v:
Pharmaceutical Research. 39:3197-3208
Precipitation of amorphous solid dispersions has gained traction in the pharmaceutical industry given its application to pharmaceuticals with varying physicochemical properties. Although preparing co-precipitated amorphous dispersions (cPAD) in high-
Publikováno v:
Powders; Volume 1; Issue 2; Pages: 88-110
The advantage of nanoparticles to improve bioavailability of poorly soluble drugs is well known. However, the higher-energy state of nanoparticles beneficial for bioavailability presents challenges for both the stability of nanosuspensions and preven
Autor:
Marina A. Solomos, Ashish Punia, Sugandha Saboo, Christopher John, Christopher W. Boyce, Alexander Chin, Robert V. Taggart, Daniel Smith, Matthew S. Lamm, Luke Schenck
Publikováno v:
Journal of Pharmaceutical Sciences.
Autor:
Tze Ning Hiew, Sugandha Saboo, Dmitry Y. Zemlyanov, Ashish Punia, Michael Wang, Daniel Smith, Michael Lowinger, Marina A. Solomos, Luke Schenck, Lynne S. Taylor
Publikováno v:
Journal of Pharmaceutical Sciences.
Co-precipitation is an emerging manufacturing strategy for amorphous solid dispersions (ASDs). Herein, the interplay between processing conditions, surface composition and release performance was evaluated using grazoprevir and hypromellose acetate s
Autor:
Ashish Punia, Kevin Lee, Edward He, Sumit Mukherjee, Andrew Mancuso, Probal Banerjee, Nan-Loh Yang
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 10, Pp 23867-23880 (2015)
Synthetic amphiphilic polymers have been established as potentially efficient agents to combat widespread deadly infections involving antibiotic resistant superbugs. Incorporation of poly(ethylene glycol) (PEG) side chains into amphiphilic copolymers
Externí odkaz:
https://doaj.org/article/53b4b2da2cbc44c2a4950888e907b371
Autor:
Derek S. Frank, Haichen Nie, Anagha Chandra, Alexander Coelho, Chad Dalton, Hannah Dvorak, Ahmed Elkhabaz, Mairead Fahy, James Ormes, Andrew Parker, Ashish Punia, Jasmine Rowe, Luke Schenck, Daniel Smith, Neil A. Strotman, Michael Wang, Laura Wareham
Publikováno v:
Journal of Pharmaceutical Sciences.
Amorphous solid dispersions (ASDs) are an attractive option to improve the bioavailability of poorly water-soluble compounds. However, the material attributes of ASDs can present formulation and processability challenges, which are often mitigated by
Publikováno v:
Journal of pharmaceutical sciences.
Amorphous solid dispersions (ASDs) have been widely utilized to enhance the bioavailability of pharmaceutical drugs with poor aqueous solubility. The role of various excipients on the amorphous drug to crystalline form conversion in ASDs has been wid
Autor:
Lina Liu, Rahul Upadhya, Adam J. Gormley, Matthew S. Lamm, Timothy Rhodes, Mythili J. Kanagala, Ashish Punia
Publikováno v:
ACS Appl Polym Mater
In pharmaceutical oral drug delivery development, about 90% of drugs in the pipeline have poor aqueous solubility leading to severe challenges with oral bioavailability and translation to effective and safe drug products. Amorphous solid dispersions
Autor:
Madeline B. Gelb, Ashish Punia, Shari Sellers, Parul Kadakia, James D. Ormes, Nazia N. Khawaja, Jennifer Wylie, Matthew S. Lamm
Publikováno v:
Journal of Drug Delivery Science and Technology. 68:103112
Autor:
Jimmie E. Fata, Ashish Punia, Kaushiki Chatterjee, Sumit Mukherjee, Nan-Loh Yang, Kamia Punia, Probal Banerjee, Krishnaswami Raja
Publikováno v:
RSC Advances. 7:10192-10199
The global health threat of antimicrobial resistance has created a pressing need to develop practical alternatives to conventional antibiotic agents. Peptide mimetic synthetic amphiphilic polymers are known to non-specifically disrupt the bacterial c