Výsledky vyhledávání - "Ashini Jayasuriya"

Darunavir concentrations exceed the protein-corrected EC50 for wild-type HIV in the semen of HIV-1-infected men

Autor: Stephen Taylor, Laura Else, David Back, Gerry Gilleran, Amanda Berry, Ngozi E. Dufty, Erasmus J Smit, Ashini Jayasuriya

Publikováno v: AIDS. 24:2583-2587

Variable antiretroviral drug penetration into the genital tract may contribute to the differential evolution of HIV-1 and the emergence of drug resistance. We compared concentrations of darunavir in 34 time-matched blood plasma and seminal plasma sam

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b205a1dadb11a249dd875238a68afb06
https://doi.org/10.1097/qad.0b013e32833ead18

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Lopinavir/ritonavir single agent therapy as a universal combination antiretroviral therapy stopping strategy: results from the STOP 1 and STOP 2 studies

Autor: Ashini Jayasuriya, Erasmus Smit, Andrew Owen, David Back, Sris Allan, Stephen Taylor, Ed Wilkins, Lisa Heald, Gerry Gilleran, Martin Fisher, Sarah Fidler

Publikováno v: The Journal of antimicrobial chemotherapy. 67(3)

We designed two different studies to evaluate two different combination antiretroviral therapy (cART) stopping strategies namely a 'staggered stop' approach (STOP 1 study) and a 'protected stop' approach (STOP 2 study) to find the best 'universal sto

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a93d9c637ccb97401aef4983f34afae
https://pubmed.ncbi.nlm.nih.gov/22169189

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Using HIV resistance tests in clinical practice

Autor: Erasmus Smit, Stephen M. Taylor, Ashini Jayasuriya

Publikováno v: The Journal of antimicrobial chemotherapy. 64(2)

Genotypic resistance testing is now a standard of care in HIV management. Although there are clear, published guidelines to recommend the appropriate use of these tests, clinicians and scientists still struggle to determine the optimal use of resista

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2b7814248ef474d994c9784d794588a
https://pubmed.ncbi.nlm.nih.gov/19535382

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Apolipoprotein E- 4 and recurrent genital herpes in individuals co-infected with herpes simplex virus type 2 and HIV

Autor: David White, Ashini Jayasuriya, Ruth Noone, Matthew A. Wozniak, Gerry Gilleran, Erasmus Smit, Steve Taylor, Rajul Patel, Ruth F. Itzhaki

Publikováno v: Sexually Transmitted Infections. 84:516-517

Apolipoprotein E (APOE) alleles have been associated with the severity of, or susceptibility to, infection by various microbes. We investigated the potential association between the APOE-epsilon 4 allele and the rate of recurrence of genital herpes i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70aaf10f64d4e74f1ec5910193c3b72d
https://doi.org/10.1136/sti.2008.032367

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