Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Ashima Bhatia"'
Publikováno v:
Clinical and Translational Science, Vol 12, Iss 1, Pp 47-52 (2019)
The purpose of this study was to measure the electrocardiographic (ECG) effects of WCK 2349 (the L‐alanine ester prodrug of levonadifloxacin) at a supratherapeutic oral dose of 2,600 mg. A total of 48 healthy volunteers were randomized to treatment
Externí odkaz:
https://doaj.org/article/65032b2fa36a44a1ae8231c6c846975d
Autor:
Behram Pardiwalla, Preeti Narayan, Nimitt Nagda, A. Bopardikar, Honey Savla, Manishkumar Shah, Kedar Toraskar, Vijay R. Sharma, Ajaykumar Yadav, Ranjeet Gutte, Dhananjay Kumbhar, Ashima Bhatia, Dhaval Gohel
Publikováno v:
Journal of Current Medical Research and Opinion. 4:940-949
Objective: With few treatment options available to manage coronavirus disease 2019 (COVID-19), health systems devised strategies to manage covid-19 using repurposed drugs and revisiting older strategies, such as convalescent plasma. This study was pl
Autor:
B. S. Chandrashekar, Kalpana Sarangi, Mushtaque A Mastim, Ashima Bhatia, Manishkumar Shah, Vijay Sharma, Mugdha Gupta, Ranjeet Gutte, Anuka Sharma, Ulka Sakhalkar
Publikováno v:
Cureus. 14(5)
Background Growth factors from platelets have been emerging as a revolutionary treatment with the ability to induce cell growth in the skin, which results in retarding and reversing the aging process. Platelet-rich plasma (PRP) allows for greater rel
Autor:
Prasad K Deshpande, Ashima Bhatia, Atul Kansagara, Anusuya Patel, Mahesh Patel, Sachin Bhagwat, Jaishid Ahdal, Swapna Shripad Takalkar, Hariharan Periasamy, Satish Bhavsar, Ravindra D. Yeole, Manohar Nandanwar, Rajesh Chavan, Rishi Jain
Publikováno v:
Drug Design, Development and Therapy. 13:4351-4365
Levonadifloxacin and its prodrug alalevonadifloxacin are novel broad-spectrum anti-MRSA agents belonging to the benzoquinolizine subclass of quinolone, formulated for intravenous and oral administration, respectively. Various in vitro and in vivo stu
Publikováno v:
Clinical and Translational Science
Clinical and Translational Science, Vol 12, Iss 1, Pp 47-52 (2019)
Clinical and Translational Science, Vol 12, Iss 1, Pp 47-52 (2019)
The purpose of this study was to measure the electrocardiographic (ECG) effects of WCK 2349 (the L‐alanine ester prodrug of levonadifloxacin) at a supratherapeutic oral dose of 2,600 mg. A total of 48 healthy volunteers were randomized to treatment
Autor:
Piotr Iwanowski, Ashima Bhatia, Rajesh Chavan, Anasuya Patel, Mugdha Gupta, David Friedland, Ravindra D. Yeole
Publikováno v:
Antimicrob Agents Chemother
Nafithromycin (WCK 4873), a novel lactone-ketolide, was administered to healthy adult subjects in 2 randomized, double-blind, placebo-controlled, phase 1 studies. In the first-in-human study, single ascending oral doses of nafithromycin (100 to 1,200
Autor:
Shraddha Tawade, K. M. Prasanna Kumar, Ashima Bhatia, Mathangi Gopalakrishnan, Eliford Ngaimisi Kitabi, Mushtaque Mastim, Dipak Thakur, Sridhar Yeshamaina, Joga Gobburu, Maharaj K. Sahib, Manish Shah
Publikováno v:
Acta Diabetologica. 55:461-468
The objective of the study was to compare the pharmacokinetic (PK) and pharmacodynamic (PD) properties of an insulin glargine formulation, Glaritus® (test) with the innovator’s formulation Lantus® (reference) using the euglycemic clamp technique
Autor:
Ashima Bhatia, Shraddha Tawade, Mushtaque Mastim, Eliford Ngaimisi Kitabi, Mathangi Gopalakrishnan, Manish Shah, Sridhar Yeshamaina, Joga Gobburu, Maharaj Sahib, Dipak Thakur, K. M. Prasanna Kumar
Publikováno v:
Acta Diabetologica. 58:129-130
Autor:
Christopher J. Kemper, Rajesh Chavan, Mushtaque Mastim, Ravindra D. Yeole, Ashima Bhatia, Allan Xu, H. David Friedland, Dyal C. Garg, Richard A. Preston, Grigor Mamikonyan
Publikováno v:
Antimicrobial agents and chemotherapy. 63(10)
WCK 4282 is a combination product of cefepime (FEP) and tazobactam (TAZ) in a 1:1 ratio currently under development for the treatment of multidrug-resistant Gram-negative bacterial infections. We investigated the effect of renal impairment on the pha
Autor:
Grigor Mamikonyan, Christopher J. Kemper, Stephane DeGraff, Allan Xu, Ashima Bhatia, Anasuya Patel, Mushtaque Mastim, Rajesh Chavan, James Chiou, Richard A. Preston, H. David Friedland, Ravindra D. Yeole
Publikováno v:
Antimicrobial agents and chemotherapy. 63(1)
WCK 5222 is a novel β-lactam–β-lactam-enhancer combination of cefepime (FEP) and zidebactam (ZID). ZID is a novel β-lactam enhancer with a dual action of binding to Gram-negative penicillin-binding protein 2 (PBP2) and β-lactamase inhibition. W