Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Ashim Subedee"'
Autor:
Bojana Jovanović, Daniel Temko, Laura E. Stevens, Marco Seehawer, Anne Fassl, Katherine Murphy, Jayati Anand, Kodie Garza, Anushree Gulvady, Xintao Qiu, Nicholas W. Harper, Veerle W. Daniels, Huang Xiao-Yun, Jennifer Y. Ge, Maša Alečković, Jason Pyrdol, Kunihiko Hinohara, Shawn B. Egri, Malvina Papanastasiou, Raga Vadhi, Alba Font-Tello, Robert Witwicki, Guillermo Peluffo, Anne Trinh, Shaokun Shu, Benedetto Diciaccio, Muhammad B. Ekram, Ashim Subedee, Zachary T. Herbert, Kai W. Wucherpfennig, Anthony G. Letai, Jacob D. Jaffe, Piotr Sicinski, Myles Brown, Deborah Dillon, Henry W. Long, Franziska Michor, Kornelia Polyak
Publikováno v:
Cell Reports, Vol 42, Iss 12, Pp 113564- (2023)
Summary: Triple-negative breast cancer (TNBC) is a heterogeneous disease with limited treatment options. To characterize TNBC heterogeneity, we defined transcriptional, epigenetic, and metabolic subtypes and subtype-driving super-enhancers and transc
Externí odkaz:
https://doaj.org/article/5b7a46fb42fa443eac6a172b0b60048f
Autor:
Brittany Connors, Xing‐Jian Lou, Ashim Subedee, Kehui Zhang, Michael Weingarten, Deepa Narayanan
Publikováno v:
Clinical and Translational Science, Vol 14, Iss 6, Pp 2124-2131 (2021)
Abstract The National Cancer Institute’s Small Business Innovation Research Development Center (NCI SBIR) provides federal research and development funding and commercialization resources to more than 400 small businesses each year developing novel
Externí odkaz:
https://doaj.org/article/99b048b64e4f4415b7db189201213697
Autor:
Ying Su, Ashim Subedee, Noga Bloushtain-Qimron, Virginia Savova, Marcin Krzystanek, Lewyn Li, Andriy Marusyk, Doris P. Tabassum, Alexander Zak, Mary Jo Flacker, Mei Li, Jessica J. Lin, Saraswati Sukumar, Hiromu Suzuki, Henry Long, Zoltan Szallasi, Alexander Gimelbrant, Reo Maruyama, Kornelia Polyak
Publikováno v:
Cell Reports, Vol 11, Iss 10, Pp 1549-1563 (2015)
Basal-like and luminal breast tumors have distinct clinical behavior and molecular profiles, yet the underlying mechanisms are poorly defined. To interrogate processes that determine these distinct phenotypes and their inheritance pattern, we generat
Externí odkaz:
https://doaj.org/article/6f15bf7525f7429da61f9bca90408f78
Autor:
Kornelia Polyak, Jason S. Carroll, Carlos Caldas, Andrew H. Beck, Oscar M. Rueda, Clive S. D'Santos, Andriy Marusyk, Ying Su, Katherine Murphy, Evangelia K. Papachristou, Chandra Sekhar Reddy Chilamakuri, Anne Trinh, Francisco Beca, Laura E. Stevens, Felipe Flores, Bojana Jovanović, Natalie Kingston, Nicholas W. Harper, Ashim Subedee, Guillermo Peluffo
Supplementary Figure S1. Transcription factors enriched in TNBC. Supplementary Figure S2. EN1 is a dependency in TNBC cell lines. Supplementary Figure S3. Transcriptional and genomic targets of EN1 in TNBC cells. Supplementary Figure S4. The effect o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::658c98b4219b2e3179638ae9f9eefb09
https://doi.org/10.1158/0008-5472.22422632.v1
https://doi.org/10.1158/0008-5472.22422632.v1
Autor:
Kornelia Polyak, Jason S. Carroll, Carlos Caldas, Andrew H. Beck, Oscar M. Rueda, Clive S. D'Santos, Andriy Marusyk, Ying Su, Katherine Murphy, Evangelia K. Papachristou, Chandra Sekhar Reddy Chilamakuri, Anne Trinh, Francisco Beca, Laura E. Stevens, Felipe Flores, Bojana Jovanović, Natalie Kingston, Nicholas W. Harper, Ashim Subedee, Guillermo Peluffo
List of TLE3 and beta-catenin peaks in SUM149 and SUM159 cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd289c9cb79ad5301fe5bae020f082c7
https://doi.org/10.1158/0008-5472.22422614.v1
https://doi.org/10.1158/0008-5472.22422614.v1
Autor:
Kornelia Polyak, Jason S. Carroll, Carlos Caldas, Andrew H. Beck, Oscar M. Rueda, Clive S. D'Santos, Andriy Marusyk, Ying Su, Katherine Murphy, Evangelia K. Papachristou, Chandra Sekhar Reddy Chilamakuri, Anne Trinh, Francisco Beca, Laura E. Stevens, Felipe Flores, Bojana Jovanović, Natalie Kingston, Nicholas W. Harper, Ashim Subedee, Guillermo Peluffo
To define transcriptional dependencies of triple-negative breast cancer (TNBC), we identified transcription factors highly and specifically expressed in primary TNBCs and tested their requirement for cell growth in a panel of breast cancer cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::716d40d7394039e0e0c4b84212ad69ad
https://doi.org/10.1158/0008-5472.c.6511289.v1
https://doi.org/10.1158/0008-5472.c.6511289.v1
Autor:
Dickran Kazandjian, Julie A. Schneider, Emma C. Scott, Yutao Gong, Julia A. Beaver, Ashim Subedee, Richard Pazdur, V. Ashutosh Rao
Publikováno v:
Journal of Clinical Oncology. 38:e14067-e14067
e14067 Background: Traditional chemotherapy agents are cytotoxic and typically act on all rapidly dividing cells. In contrast, targeted cancer therapies take advantage of unique genetic or proteomic susceptibility in cancer cells, their microenvironm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8acfff5741e10fe2a150764d1937db4
https://doi.org/10.1200/jco.2020.38.15_suppl.e14067
https://doi.org/10.1200/jco.2020.38.15_suppl.e14067
Autor:
Virginia Savova, Reo Maruyama, Henry W. Long, Mei Li, Lewyn Li, Hiromu Suzuki, Jessica J. Lin, Kornelia Polyak, Andriy Marusyk, Noga Bloushtain-Qimron, Alexander Zak, Ying Su, Alexander A. Gimelbrant, Mary Jo Flacker, Doris P. Tabassum, Ashim Subedee, Saraswati Sukumar, Marcin Krzystanek, Zoltan Szallasi
Publikováno v:
Su, Y, Subedee, A, Bloushtain-Qimron, N, Savova, V, Krzystanek, M, Li, L, Marusyk, A, Tabassum, D P, Zak, A & Szallasi, Z I 2015, ' Somatic Cell Fusions Reveal Extensive Heterogeneity in Basal-like Breast Cancer ', Cell Reports, vol. 11, no. 10, pp. 1549-1563 . https://doi.org/10.1016/j.celrep.2015.05.011
Cell Reports, Vol 11, Iss 10, Pp 1549-1563 (2015)
Cell Reports, Vol 11, Iss 10, Pp 1549-1563 (2015)
Basal-like and luminal breast tumors have distinct clinical behavior and molecular profiles, yet the underlying mechanisms are poorly defined. To interrogate processes that determine these distinct phenotypes and their inheritance pattern, we generat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b855ee87aee60aca7d90a865ae1ec20
https://doi.org/10.1016/j.celrep.2015.05.011
https://doi.org/10.1016/j.celrep.2015.05.011
Publikováno v:
Applied and environmental microbiology. 73(24)
Bacterial leaf streak, caused by Xanthomonas oryzae pv. oryzicola, is an important disease of rice. Transposon-mediated mutational analysis of the pathogen with a quantitative assay revealed candidate virulence factors including genes involved in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4cbdab52e92735a9cc529f3bbd3613a
https://pubmed.ncbi.nlm.nih.gov/17981946
https://pubmed.ncbi.nlm.nih.gov/17981946