Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Ashim Mukherjee"'
Publikováno v:
eLife, Vol 12 (2024)
The Wnt/Wg pathway controls myriads of biological phenomena throughout the development and adult life of all organisms across the phyla. Thus, an aberrant Wnt signaling is associated with a wide range of pathologies in humans. Tight regulation of Wnt
Externí odkaz:
https://doaj.org/article/9e24b8f92bd74842abbce1aed95d451c
Autor:
Rituparna Das, Pranjali Pandey, Bhawana Maurya, Priyadarshika Pradhan, Devanjan Sinha, Ashim Mukherjee, Mousumi Mutsuddi
Publikováno v:
European Journal of Cell Biology, Vol 102, Iss 2, Pp 151300- (2023)
A-kinase anchoring protein (AKAP) comprises a family of scaffold proteins, which decides the subcellular localisation of a combination of signalling molecules. Spoonbill (Spoon) is a putative A-kinase anchoring protein in Drosophila. We have earlier
Externí odkaz:
https://doaj.org/article/d1258064dd9649f0a7fa1520f6f02d43
Autor:
Bhawana Maurya, Satya Surabhi, Rituparna Das, Pranjali Pandey, Ashim Mukherjee, Mousumi Mutsuddi
Publikováno v:
Cell Death and Disease, Vol 12, Iss 4, Pp 1-14 (2021)
Abstract Maheshvara (mahe), an RNA helicase that is widely conserved across taxa, regulates Notch signaling and neuronal development in Drosophila. In order to identify novel components regulated by mahe, transcriptome profiling of ectopic mahe was c
Externí odkaz:
https://doaj.org/article/cd7979eed9cd40ff9e69c456425eaefd
Autor:
Rakesh Mishra, Rohit Kunar, Lolitika Mandal, Debasmita Pankaj Alone, Shanti Chandrasekharan, Anand Krishna Tiwari, Madhu Gwaldas Tapadia, Ashim Mukherjee, Jagat Kumar Roy
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 10, Iss 8, Pp 2601-2618 (2020)
The use of transposons to create mutations has been the cornerstone of Drosophila genetics in the past few decades. Second-site mutations caused by transpositions are often devoid of transposons and thereby affect subsequent analyses. In a P-element
Externí odkaz:
https://doaj.org/article/4957e7a258df44c09ddd5ee9e4ba5f39
Publikováno v:
BMC Research Notes, Vol 11, Iss 1, Pp 1-9 (2018)
Abstract Objectives Oncogenic potential of Notch signaling and its cooperation with other factors to affect proliferation are widely established. Notch exhibits a cooperative effect with loss of a cell polarity gene, scribble to induce neoplastic ove
Externí odkaz:
https://doaj.org/article/b273068f88a84b948b6c78c39da47d2b
Autor:
Ankita Singh, Debdeep Dutta, Maimuna Sali Paul, Dipti Verma, Mousumi Mutsuddi, Ashim Mukherjee
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 8, Iss 3, Pp 1067-1077 (2018)
Chromatin-remodeling proteins have a profound role in the transcriptional regulation of gene expression during development. Here, we have shown that the chromodomain-containing protein Hat-trick is predominantly expressed within the oocyte nucleus, s
Externí odkaz:
https://doaj.org/article/9487866addae4ffb8865e28f12b4c4a2
Autor:
Shashank Gupta, Pradeep Kumar Bhaskar, Ritu Bhardwaj, Abhishek Chandra, Vidya Nair Chaudhry, Prashaant Chaudhry, Akhtar Ali, Ashim Mukherjee, Mousumi Mutsuddi
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e103063 (2014)
Hyperhomocysteinemia induced by the C677T genetic variant in MTHFR (methylenetetrahydrofolate reductase) has been implicated in neuronal cell death of retinal ganglion cells (RGC), which is a characteristic feature of glaucoma. However, association o
Externí odkaz:
https://doaj.org/article/84b7595e7a5b4aaeaae4f941f32ad26a
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68247 (2013)
The Notch signaling pathway controls diverse cell-fate specification events throughout development. The versatility of this pathway to influence different aspects of development comes from its multiple levels of regulation. Upon ligand-induced Notch
Externí odkaz:
https://doaj.org/article/b942fce47cff4211b130a08b812b5f80
Autor:
Howard Chia-Hao Chang, Douglas N Dimlich, Takakazu Yokokura, Ashim Mukherjee, Mark W Kankel, Anindya Sen, Vasanthi Sridhar, Tudor A Fulga, Anne C Hart, David Van Vactor, Spyros Artavanis-Tsakonas
Publikováno v:
PLoS ONE, Vol 3, Iss 9, p e3209 (2008)
Spinal Muscular Atrophy (SMA), a recessive hereditary neurodegenerative disease in humans, has been linked to mutations in the survival motor neuron (SMN) gene. SMA patients display early onset lethality coupled with motor neuron loss and skeletal mu
Externí odkaz:
https://doaj.org/article/dafc3ca54a234f99bc04d8a718fc5c1a
Publikováno v:
The FEBS Journal.