Zobrazeno 1 - 8 of 8 pro vyhledávání: '"Ashif I. Bhuiyan"'
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Akademický článek
Nek2 Kinase Signaling in Malaria, Bone, Immune and Kidney Disorders to Metastatic Cancers and Drug Resistance: Progress on Nek2 Inhibitor Development
Autor: Dibyendu Dana, Tuhin Das, Athena Choi, Ashif I. Bhuiyan, Tirtha K. Das, Tanaji T. Talele, Sanjai K. Pathak
Publikováno v: Molecules, Vol 27, Iss 2, p 347 (2022)
Cell cycle kinases represent an important component of the cell machinery that controls signal transduction involved in cell proliferation, growth, and differentiation. Nek2 is a mitotic Ser/Thr kinase that localizes predominantly to centrosomes and
Externí odkaz: https://doaj.org/article/b20092a5706147759b034d8e80a93c73
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2
GPR171 activation regulates morphine tolerance but not withdrawal in a test-dependent manner in mice
Autor: Leela Afrose, Max V. McDermott, Ashif I. Bhuiyan, Sanjai K. Pathak, Erin N. Bobeck
Publikováno v: Behavioural pharmacology. 33(7)
A newly deorphanized G protein-coupled receptor, GPR171, is found to be highly expressed within the periaqueductal gray, a pain-modulating region in the brain. Our recent research has shown that a GPR171 agonist increases morphine antinociception in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da12bf564834d823afb9e9e7685ff00e
https://pubmed.ncbi.nlm.nih.gov/35942845
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6
Cell penetrable, clickable and tagless activity-based probe of human cathepsin L
Autor: Karl R. Fath, Dibyendu Dana, Jeremy Garcia, Sanjai K. Pathak, Pratikkumar Rathod, Laura Joo, Daniel A. Novoa, Suneeta Paroly, Emmanuel J. Chang, Ashif I. Bhuiyan
Publikováno v: Bioorganic Chemistry. 85:505-514
Human cathepsin L is a ubiquitously expressed endopeptidase and is known to play critical roles in a wide variety of cellular signaling events. Its overexpression has been implicated in numerous human diseases, including highly invasive forms of canc
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::196198e6bb2c1b2fc560786f649308d7
https://doi.org/10.1016/j.bioorg.2019.02.032
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7
Clickable, selective, and cell-permeable activity-based probe of human cathepsin B – Minimalistic approach for enhanced selectivity
Autor: Faiza Rafi, Karl R. Fath, Anna A. Dickson, Tuhin Das, Guoshen Li, Gopal Subramaniam, Sarbani Ghoshal, Sanjai K. Pathak, Pratikkumar Rathod, Dibyendu Dana, Suneeta Paroly, Ashif I. Bhuiyan, Emmanuel J. Chang
Publikováno v: Bioorganic Chemistry. 117:105463
Human cathepsin B is a cysteine-dependent protease whose roles in both normal and diseased cellular states remain yet to be fully delineated. This is primarily due to overlapping substrate specificities and lack of unambiguously annotated physiologic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bef6f0f68d423d40501e60e4599276b
https://doi.org/10.1016/j.bioorg.2021.105463
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8
Glutathione-Garlic Sulfur Conjugates: Slow Hydrogen Sulfide Releasing Agents for Therapeutic Applications
Autor: Maurizio Paci, Vilma Toska Papajani, Sonia Melino, Ashif I. Bhuiyan
Publikováno v: Molecules
Volume 20
Issue 1
Pages 1731-1750
Molecules, Vol 20, Iss 1, Pp 1731-1750 (2015)
Natural organosulfur compounds (OSCs) from Allium sativum L. display antioxidant and chemo-sensitization properties, including the in vitro inhibition of tumor cell proliferation through the induction of apoptosis. Garlic water- and oil-soluble allyl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b05eac4f069a1445d109f5bcd9cd1404
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