Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Ashgan Bishara"'
Autor:
Nathalie Ben-Califa, Drorit Neumann, Maurice Aknin, Ashgan Bishara, Lee Goren Zur, Yoel Kashman
Publikováno v:
Marine Drugs, Vol 11, Iss 11, Pp 4487-4509 (2013)
Derivatives of salarin A, salarin C and tulearin A, three new cytotoxic sponge derived nitrogenous macrolides, were prepared and bio-evaluated as inhibitors of K562 leukemia cells. Interesting preliminary SAR (structure activity relationship) informa
Externí odkaz:
https://doaj.org/article/6bcbb84fc4a64c88a4b38766e8c5dd37
Publikováno v:
Marine Drugs, Vol 8, Iss 11, Pp 2810-2836 (2010)
A large variety of unique N-atom containing compounds (alkaloids) without terrestrial counterparts, have been isolated from marine invertebrates, mainly sponges and ascidians. Many of these compounds display interesting biological activities. In this
Externí odkaz:
https://doaj.org/article/66fe8b051bfd47e0ba4a07b2e2f8444c
Salarin C, a member of the salarin superfamily of marine compounds, is a potent inducer of apoptosis
Publikováno v:
Investigational New Drugs. 30:98-104
The continuous emergence of new diseases and the development of drug-resistant cancers necessitate the development of new drugs with novel mechanisms of action. The richest marine source of natural anti-cancer products has been soft-bodied organisms
Autor:
Yehuda Benayahu, Ashgan Bishara, Michael H. Schleyer, Guy Shmul, Yoel Kashman, Dina Yeffet, Mor Sisso, Amira Rudi
Publikováno v:
Journal of Natural Products. 71:375-380
Ten new sesquiterpenes, nardosinanols A-I ( 1- 9) and lemnafricanol ( 10), have been isolated from several Kenyan soft corals, i.e., from Lemnalia sp., Paralemnalia clavata, Lemnalia africana, and Rhytisma fulvum fulvum. The structures and relative s
Novaxenicins A–D and xeniolides I–K, seven new diterpenes from the soft coral Xenia novaebrittanniae
Publikováno v:
Tetrahedron. 62:12092-12097
Seven new diterpenes, novaxenicins A–D (1–4) and xeniolides I–K (5–7), have been isolated from the Kenyan soft coral Xenia novaebrittanniae. The structures and relative stereochemistry of the compounds were elucidated by interpretation of MS,
Autor:
Ashgan Bishara, Abraham J. Domb
Publikováno v:
Journal of Controlled Release. 107:474-483
Reversible stereoselective complexes were spontaneously formed from mixing acetonitrile solutions of enantiomeric D-poly(lactide) (D-PLA), L-poly(lactide) (L-PLA), and octreotide (an octapeptide, somatostatin analogue). Hetero-stereocomplexes of poly
Publikováno v:
Macromolecular Symposia. 225:17-30
Triblock copolymers of poly(lactide)-poly(ethylene-glycol)-poly(lactide) (ALA-PEG 2000 -PLA) were synthesized by ring-opening polymerization of lactide and PEG 2000 diol as co-catalyst. Stereocomplexes with particle sizes ranging from nanometers to m
Publikováno v:
Tetrahedron Letters
Tetrahedron Letters, Elsevier, 2009, 50 (27), pp.3820--3822. ⟨10.1016/j.tetlet.2009.04.028⟩
Tetrahedron Letters, Elsevier, 2009, 50 (27), pp.3820--3822. ⟨10.1016/j.tetlet.2009.04.028⟩
International audience; The relative configuration of tulearin A I (R3 = H, R8 = CONH2, R9 = H) was detd. by X-ray diffraction anal. of a cyclic carbonate deriv. I (R3 = H, R8R9 = CO), and the abs. configuration (2R,3R,5S,8S,9S,15R,17S) from the 9-MT
Autor:
Lee Goren Zur, Yoel Kashman, Nathalie Ben-Califa, Maurice Aknin, Drorit Neumann, Ashgan Bishara
Publikováno v:
Marine Drugs; Volume 11; Issue 11; Pages: 4487-4509
Marine Drugs, Vol 11, Iss 11, Pp 4487-4509 (2013)
Marine drugs
Marine drugs, MDPI, 2013, 11 (11), pp.4487-4509. ⟨10.3390/md11114487⟩
Marine Drugs
Marine Drugs, Vol 11, Iss 11, Pp 4487-4509 (2013)
Marine drugs
Marine drugs, MDPI, 2013, 11 (11), pp.4487-4509. ⟨10.3390/md11114487⟩
Marine Drugs
International audience; Derivatives of salarin A, salarin C and tulearin A, three new cytotoxic sponge derived nitrogenous macrolides, were prepared and bio-evaluated as inhibitors of K562 leukemia cells. Interesting preliminary SAR (structure activi
Publikováno v:
Planta Medica
International Congress on Natural Products Research
International Congress on Natural Products Research, Jul 2012, New York City, United States. pp.CL25, ⟨10.1055/s-0032-1320260⟩
International Congress on Natural Products Research
International Congress on Natural Products Research, Jul 2012, New York City, United States. pp.CL25, ⟨10.1055/s-0032-1320260⟩
International audience; Nitrogenous compounds isolated from the Madagascan sponge Fascaplysinopsis sp, namely, four groups of secondary metabolites, salarins, tulearins, taumycins and tausalarin are represented. As well as several salarin C derivativ