Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Asher M. Kahn-Krell"'
Publikováno v:
iScience, Vol 25, Iss 3, Pp 103824- (2022)
Summary: Human cardiac-muscle patches (hCMPs) constructed from induced pluripotent stem cells derived cardiomyocytes (iCMs) can replicate the genetics of individual patients, and consequently be used for drug testing, disease modeling, and therapeuti
Externí odkaz:
https://doaj.org/article/9a287071f4764a90b5a4c6c09e927e28
Autor:
Danielle Pretorius, Asher M. Kahn-Krell, Xi Lou, Vladimir G. Fast, Joel L. Berry, Timothy J. Kamp, Jianyi Zhang
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Engineered cardiac tissues fabricated from human induced pluripotent stem cells (hiPSCs) show promise for ameliorating damage from myocardial infarction, while also restoring function to the damaged left ventricular (LV) myocardium. For these constru
Externí odkaz:
https://doaj.org/article/9189e6903dac46af8370dd6031f81b18
Autor:
Wesley LaBarge, Andrés Morales, Daniëlle Pretorius, Asher M. Kahn-Krell, Ramaswamy Kannappan, Jianyi Zhang
Publikováno v:
Micromachines, Vol 10, Iss 9, p 570 (2019)
Free from the limitations posed by exogenous scaffolds or extracellular matrix-based materials, scaffold-free engineered tissues have immense clinical potential. Biomaterials may produce adverse responses, interfere with cell–cell interaction, or a
Externí odkaz:
https://doaj.org/article/8866dd7af930458e9fb7d78c7cadba33
Autor:
Xi Lou, Yawen Tang, Lei Ye, Danielle Pretorius, Vladimir G Fast, Asher M Kahn-Krell, Jue Zhang, Jianhua Zhang, Aijun Qiao, Gangjian Qin, Timothy Kamp, James A Thomson, Jianyi Zhang
Publikováno v:
Cardiovascular Research. 119:1062-1076
Aims We have shown that human cardiac muscle patches (hCMPs) containing three different types of cardiac cells—cardiomyocytes (CMs), smooth muscle cells (SMCs), and endothelial cells (ECs), all of which were differentiated from human pluripotent st