Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Asher K. Haug-Baltzell"'
Autor:
Andrew D. L. Nelson, Upendra K. Devisetty, Kyle Palos, Asher K. Haug-Baltzell, Eric Lyons, Mark A. Beilstein
Publikováno v:
Frontiers in Genetics, Vol 8 (2017)
Long intergenic non-coding RNAs (lincRNAs) are an abundant and functionally diverse class of eukaryotic transcripts. Reported lincRNA repertoires in mammals vary, but are commonly in the thousands to tens of thousands of transcripts, covering ~90% of
Externí odkaz:
https://doaj.org/article/c05cf2d79db64a8083bd6293a559939b
Autor:
Yong Wang, Robert Burton, Cecily Vaughn, Miao Zhang, Brooke Rhead, Heather Harris, Spencer C Knight, Shannon R McCurdy, Marie V Coignet, Danny S Park, Genevieve H L Roberts, Nathan D Berkowitz, David Turissini, Karen Delgado, Milos Pavlovic, Asher K Haug Baltzell, Harendra Guturu, Kristin A Rand, Ahna R Girshick, Eurie L Hong, Catherine A Ball, Yambazi Banda, Ke Bi, Marjan Champine, Ross Curtis, Abby Drokhlyansky, Ashley Elrick, Cat Foo, Michael Gaddis, Jialiang Gu, Shannon Hateley, Shea King, Christine Maldonado, Evan McCartney-Melstad, Alexandra McFarland, Patty Miller, Luong Nguyen, Keith Noto, Jingwen Pei, Jenna Petersen, Scott Pew, Chodon Sass, Josh Schraiber, Alisa Sedghifar, Andrey Smelter, Sarah South, Barry Starr
Publikováno v:
BMJ Open, Vol 12, Iss 10 (2022)
Objectives The enormous toll of the COVID-19 pandemic has heightened the urgency of collecting and analysing population-scale datasets in real time to monitor and better understand the evolving pandemic. The objectives of this study were to examine t
Externí odkaz:
https://doaj.org/article/3d91f05ab0d54f8ea55c2becf75f8e4a
Autor:
Marie V. Coignet, Eurie L. Hong, Sarah South, Miao Zhang, Harendra Guturu, Pei Jingwen, Jialiang Gu, Brooke Rhead, Michael Gaddis, Cecily Vaughn, Luong Ruiz, Nathan Berkowitz, Cat Foo, Ashley Elrick, Christine Maldonado, Ahna R. Girshick, Heather H. Harris, Ke Bi, Marjan Champine, Evan McCartney-Melstad, Spencer C. Knight, Keith Noto, Barry Starr, Milos Pavlovic, David A. Turrisini, Robert Burton, Kristin A. Rand, Ross E. Curtis, Shea King, Andrey Smelter, Karen Delgado, Yambazi Banda, Asher K. Haug Baltzell, Alisa Sedghifar, Raghavendran Partha, Yong Wang, Abby Drokhlyansky, Genevieve H.L. Roberts, Chodon Sass, Jenna Petersen, Patty Miller, Danny S. Park, Catherine A. Ball, Shannon R. McCurdy
INTRODUCTION PARAGRAPHMultiple large COVID-19 genome-wide association studies (GWAS) have identified reproducible genetic associations indicating that some infection susceptibility and severity risk is heritable.1-5 Most of these studies ascertained
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a680e1c5a57d19fa29d6b35999852a32
https://doi.org/10.1101/2021.01.24.21250324
https://doi.org/10.1101/2021.01.24.21250324
Autor:
Genevieve H L, Roberts, Raghavendran, Partha, Brooke, Rhead, Spencer C, Knight, Danny S, Park, Marie V, Coignet, Miao, Zhang, Nathan, Berkowitz, David A, Turrisini, Michael, Gaddis, Shannon R, McCurdy, Milos, Pavlovic, Luong, Ruiz, Chodon, Sass, Asher K, Haug Baltzell, Harendra, Guturu, Ahna R, Girshick, Catherine A, Ball, Eurie L, Hong, Kristin A, Rand
Publikováno v:
Nature genetics. 54(4)
Multiple COVID-19 genome-wide association studies (GWASs) have identified reproducible genetic associations indicating that there is a genetic component to susceptibility and severity risk. To complement these studies, we collected deep coronavirus d
Autor:
Marie V. Coignet, Dylan Sun, Lukas Habegger, Evan Maxwell, Daniel J. Rader, David J. Carey, Katherine A. Siminovitch, Giorgio Sirugo, Anne E. Justice, Joelle Mbatchou, Eli A. Stahl, Gonçalo R. Abecasis, Alexander H. Li, David A. Turissini, Adam E. Locke, Kristin A. Rand, Aris Baras, Joseph B. Leader, Genevieve H.L. Roberts, Ahna R. Girshick, Deepika Sharma, Nilanjana Banerjee, Fabricio S. P. Kury, John D. Overton, Shane McCarthy, Jonathan Marchini, Xiaodong Bai, Eurie L. Hong, Rouel Lanche, Amy Damask, Ashish Yadav, Raghavendran Partha, Shannon R. McCurdy, Miao Zhang, Suganthi Balasubramanian, Hyun Min Kang, Anurag Verma, Marcus B. Jones, Marylyn D. Ritchie, Colm O'Dushlaine, Manuel A. R. Ferreira, Adam J. Mansfield, Anthony Marcketta, Joshua D. Backman, Alan R. Shuldiner, Michael N. Cantor, Tooraj Mirshahi, Lee Dobbyn, Spencer C. Knight, William J Salerno, Harenda Guturu, Jeffrey G. Reid, Julie E. Horowitz, Lauren Gurski, Danny S. Park, Kyoko Watanabe, Catherine A. Ball, Asher K. Haug Baltzell, Jack A. Kosmicki
SARS-CoV-2 enters host cells by binding angiotensin-converting enzyme 2 (ACE2). Through a genome-wide association study, we show that a rare variant (MAF = 0.3%, odds ratio 0.60, P=4.5x10-13) that down-regulates ACE2 expression reduces risk of COVID-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e1331fb38faa9a04f624deb1333af5b
https://doi.org/10.1101/2020.12.14.20248176
https://doi.org/10.1101/2020.12.14.20248176
Autor:
Catherine A. Ball, Genevieve H.L. Roberts, Shannon R. McCurdy, Eurie L. Hong, Karen Delgado, Danny S. Park, Brooke Rhead, Harendra Guturu, Milos Pavlovic, Asher K. Haug Baltzell, Marie V. Coignet, Miao Zhang, David A. Turissini, Kristin A. Rand, Ahna R. Girshick, Nathan Berkowitz, Spencer C. Knight
BackgroundThe enormous toll of the COVID-19 pandemic has heightened the urgency of collecting and analyzing population-scale datasets in real time to monitor and better understand the evolving pandemic.MethodsThe AncestryDNA COVID-19 Study collected
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb2ab3de1981e7dd53b5fe356a295417
https://doi.org/10.1101/2020.10.08.20209593
https://doi.org/10.1101/2020.10.08.20209593
Autor:
Harendra Guturu, Shannon R. McCurdy, Genevieve H.L. Roberts, Ahna R. Girshick, Asher K. Haug Baltzell, Brooke Rhead, Raghavendran Partha, Marie V. Coignet, Miao Zhang, Spencer C. Knight, Catherine A. Ball, Nathan Berkowitz, Kristin A. Rand, Danny S. Park, Eurie L. Hong
Human infection with SARS-CoV-2, the causative agent of COVID-19, leads to a remarkably diverse spectrum of outcomes, ranging from asymptomatic to fatal. Recent reports suggest that both clinical and genetic risk factors may contribute to COVID-19 su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3e832baec5b6ce8e344e9055e50c001
https://doi.org/10.1101/2020.10.06.20205864
https://doi.org/10.1101/2020.10.06.20205864
Autor:
Blake L, Joyce, Asher K, Haug-Baltzell, Jonathan P, Hulvey, Fiona, McCarthy, Upendra Kumar, Devisetty, Eric, Lyons
Publikováno v:
Journal of Visualized Experiments : JoVE
This workflow allows novice researchers to leverage advanced computational resources such as cloud computing to carry out pairwise comparative transcriptomics. It also serves as a primer for biologists to develop data scientist computational skills,