Molecular mechanism of BMP signal control by Twisted gastrulation.

Autor: Malinauskas T; Division of Structural Biology, Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7BN, UK. tomas@strubi.ox.ac.uk., Moore G; Faculty of Biology, Medicine and Health, University of Manchester, Manchester, M13 9PT, UK., Rudolf AF; Division of Structural Biology, Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7BN, UK., Eggington H; Intestinal Stem Cell Biology Lab, Wellcome Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK.; Translational Gastroenterology Unit, John Radcliffe Hospital, University of Oxford, Oxford National Institute for Health Research Biomedical Research Centre, Oxford, UK., Belnoue-Davis HL; Intestinal Stem Cell Biology Lab, Wellcome Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK.; Translational Gastroenterology Unit, John Radcliffe Hospital, University of Oxford, Oxford National Institute for Health Research Biomedical Research Centre, Oxford, UK., El Omari K; Diamond Light Source, Harwell Science and Innovation Campus, Didcot, OX11 0DE, UK., Griffiths SC; Division of Structural Biology, Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7BN, UK.; Evotec (UK) Ltd., 90 Innovation Drive, Milton Park, Abingdon, OX14 4RZ, UK., Woolley RE; Division of Structural Biology, Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7BN, UK.; Etcembly Ltd., Atlas Building, Harwell Campus, OX11 0QX, UK., Duman R; Diamond Light Source, Harwell Science and Innovation Campus, Didcot, OX11 0DE, UK., Wagner A; Diamond Light Source, Harwell Science and Innovation Campus, Didcot, OX11 0DE, UK., Leedham SJ; Intestinal Stem Cell Biology Lab, Wellcome Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK.; Translational Gastroenterology Unit, John Radcliffe Hospital, University of Oxford, Oxford National Institute for Health Research Biomedical Research Centre, Oxford, UK., Baldock C; Wellcome Centre for Cell-Matrix Research, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, Manchester, M13 9PT, UK., Ashe HL; Faculty of Biology, Medicine and Health, University of Manchester, Manchester, M13 9PT, UK. hilary.ashe@manchester.ac.uk., Siebold C; Division of Structural Biology, Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7BN, UK. christian@strubi.ox.ac.uk.

Publikováno v: Nature communications [Nat Commun] 2024 Jun 11; Vol. 15 (1), pp. 4976. Date of Electronic Publication: 2024 Jun 11.

Combined modelling of mRNA decay dynamics and single-molecule imaging in the Drosophila embryo uncovers a role for P-bodies in 5' to 3' degradation.

Autor: Forbes Beadle L; Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom., Love JC; Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom., Shapovalova Y; Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom., Artemev A; Department of Computing, Imperial College London, London, United Kingdom., Rattray M; Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom., Ashe HL; Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom.

Publikováno v: PLoS biology [PLoS Biol] 2023 Jan 17; Vol. 21 (1), pp. e3001956. Date of Electronic Publication: 2023 Jan 17 (Print Publication: 2023).

Scalable inference of transcriptional kinetic parameters from MS2 time series data.

Autor: Bowles JR; Faculty of Biology, Medicine and Health, The University of Manchester, Manchester M13 9PT, UK., Hoppe C; Faculty of Biology, Medicine and Health, The University of Manchester, Manchester M13 9PT, UK.; Department of Genetics, Yale University School of Medicine, New Haven, CT 06510, USA., Ashe HL; Faculty of Biology, Medicine and Health, The University of Manchester, Manchester M13 9PT, UK., Rattray M; Faculty of Biology, Medicine and Health, The University of Manchester, Manchester M13 9PT, UK.

Publikováno v: Bioinformatics (Oxford, England) [Bioinformatics] 2022 Jan 27; Vol. 38 (4), pp. 1030-1036.

Live and fixed imaging of translation sites at single mRNA resolution in the Drosophila embryo.

Autor: Vinter DJ; Faculty of Biology, Medicine and Health, University of Manchester, Manchester M13 9PT, UK., Hoppe C; Faculty of Biology, Medicine and Health, University of Manchester, Manchester M13 9PT, UK., Ashe HL; Faculty of Biology, Medicine and Health, University of Manchester, Manchester M13 9PT, UK.

Publikováno v: STAR protocols [STAR Protoc] 2021 Sep 13; Vol. 2 (3), pp. 100812. Date of Electronic Publication: 2021 Sep 13 (Print Publication: 2021).

CRISPR-Cas9 strategies to insert MS2 stem-loops into endogenous loci in Drosophila embryos.

Autor: Hoppe C; Faculty of Biology, Medicine and Health, University of Manchester, Manchester M13 9PT, UK., Ashe HL; Faculty of Biology, Medicine and Health, University of Manchester, Manchester M13 9PT, UK.

Publikováno v: STAR protocols [STAR Protoc] 2021 Mar 18; Vol. 2 (1), pp. 100380. Date of Electronic Publication: 2021 Mar 18 (Print Publication: 2021).