Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Ashay D Bhatwadekar"'
Autor:
Kayla Thompson, Jonathan Chen, Qianyi Luo, Yucheng Xiao, Theodore R Cummins, Ashay D Bhatwadekar
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0193280 (2018)
Diabetic retinopathy (DR) is a major cause of adult blindness. Retinal Müller cells maintain water homeostasis and potassium concentration via inwardly rectifying Kir4.1 channels. Accumulation of advanced glycation end products (AGEs) is a major pat
Externí odkaz:
https://doaj.org/article/503ef3f8207e4bfe81d86e714c7022fa
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-12 (2024)
Abstract Background The Lin−Sca1+c-Kit+ (LSK) fraction of the bone marrow (BM) comprises multipotent hematopoietic stem cells (HSCs), which are vital to tissue homeostasis and vascular repair. While diabetes affects HSC homeostasis overall, the mol
Externí odkaz:
https://doaj.org/article/5b47f08f22ae4a41a2a6c453cb47f506
Autor:
Vaishnavi Jadhav, Qianyi Luo, James M Dominguez, Jude Al-Sabah, Brahim Chaqour, Maria B Grant, Ashay D Bhatwadekar
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0163367 (2016)
Period 2-mutant mice (Per2m/m), which possess a circadian dysfunction, recapitulate the retinal vascular phenotype similar to diabetic retinopathy (DR). The vascular dysfunction in Per2m/m is associated with an increase in connective tissue growth fa
Externí odkaz:
https://doaj.org/article/6d0bb7b96a7141a6b476ef6750b437fb
Autor:
Yuanqing Yan, Tatiana E Salazar, James M Dominguez, Dung V Nguyen, Sergio Li Calzi, Ashay D Bhatwadekar, Xiaoping Qi, Julia V Busik, Michael E Boulton, Maria B Grant
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e80029 (2013)
Dysregulation of circadian rhythmicity is identified as a key factor in disease pathogenesis. Circadian rhythmicity is controlled at both a transcriptional and post-transcriptional level suggesting the role of microRNA (miRNA) and double-stranded RNA
Externí odkaz:
https://doaj.org/article/29a7c592192a4ca69cf86dab84bfe6a8
Autor:
Sugata Hazra, Valerie Stepps, Ashay D Bhatwadekar, Sergio Caballero, Michael E Boulton, Paul J Higgins, Elena V Nikonova, Carl J Pepine, Catherine Thut, Eva M Finney, David J Stone, Stephen H Bartelmez, Maria B Grant
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e79067 (2013)
Previously, we showed that transient inhibition of TGF- β1 resulted in correction of key aspects of diabetes-induced CD34(+) cell dysfunction. In this report, we examine the effect of transient inhibition of plasminogen activator inhibitor-1 (PAI-1)
Externí odkaz:
https://doaj.org/article/46a5af6d5ea341dbaded9bbbcf0726cd
Publikováno v:
Frontiers in Ophthalmology, Vol 3 (2023)
Diabetic retinopathy (DR) is a leading cause of vision impairment. The proliferative form of DR (PDR) involves fibrovascular membrane (FVM) formation at the vitreoretinal interface. MicroRNAs (miRNAs) are a class of non-coding RNA molecules that play
Externí odkaz:
https://doaj.org/article/bb6efe0e95aa4ada8953e7508edb91e5
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Diabetic retinopathy (DR) is the most common complication of diabetes. DR is characterized by damage to retinal vasculature resulting in vision impairment and, if untreated, could eventually lead to blindness. The pathogenic mechanism of DR is comple
Externí odkaz:
https://doaj.org/article/823b9f27b7dd4601b61149d2a4da43dc
Autor:
Tong Wu, Louis M. Pelus, P. Artur Plett, Carol H. Sampson, Hui Lin Chua, Alexa Fisher, Hailin Feng, Liqiong Liu, Hongge Li, Miguel Ortiz, Supriya Chittajallu, Qianyi Luo, Ashay D. Bhatwadekar, Timothy B. Meyer, Xin Zhang, Daohong Zhou, Kathryn D. Fischer, David L. McKinzie, Steven J. Miller, Christie M. Orschell
Publikováno v:
Radiation Research. 199
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0ed66f789502c4c668a5378389a4b49
https://doi.org/10.1667/rade-22-00208.1
https://doi.org/10.1667/rade-22-00208.1
Publikováno v:
Journal of pharmacy practice.
There are three major microvascular complications of diabetes, retinopathy, nephropathy, and neuropathy, among which diabetic retinopathy (DR) is the most common. Several studies suggest that the Hispanic/LatinX population exhibit the highest cases o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::373e049f6490a242ca3e703490b73d23
https://pubmed.ncbi.nlm.nih.gov/36325719
https://pubmed.ncbi.nlm.nih.gov/36325719
Autor:
Doaa Hassan, Hunter Mathias Gill, Michael Happe, Ashay D. Bhatwadekar, Amir R. Hajrasouliha, Sarath Chandra Janga
Publikováno v:
Frontiers in medicine. 9
Diabetic retinopathy (DR) is a late microvascular complication of Diabetes Mellitus (DM) that could lead to permanent blindness in patients, without early detection. Although adequate management of DM via regular eye examination can preserve vision i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eeb1cf204bc5d50c574bd36477e0238a
https://pubmed.ncbi.nlm.nih.gov/36425113
https://pubmed.ncbi.nlm.nih.gov/36425113