Výsledky vyhledávání - "Ashanjiang Aniwan"

Akademický článek

Genistein inhibits HIF-1α and attenuates high glucose-induced peritoneal mesothelial-mesenchymal transition and fibrosis via the mTOR/OGT pathway

Autor: Jian Wang, Xin Lv, Yao Lin, Ashanjiang Aniwan, Hongyan Liu, Saijun Zhou, Pei Yu

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)

Abstract Peritoneal fibrosis has been linked to hypoxia-inducible factor 1-alpha (HIF-1α) as well as O-linked-N-acetylglucosaminylation (O-GlcNAcylation) in peritoneal dialysis (PD). Genistein, recognized for its HIF-1α inhibitory and antifibrotic

Externí odkaz: https://doaj.org/article/20e5856c3e5646b18d005437d5946abc

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Akademický článek

O-GlcNAcylation regulates HIF-1α and induces mesothelial-mesenchymal transition and fibrosis of human peritoneal mesothelial cells

Autor: Jian Wang, Xin lv, Ashanjiang Aniwan, Hongyan Liu, Yao Lin, Xian Shao, Saijun Zhou, Pei Yu

Publikováno v: Heliyon, Vol 9, Iss 12, Pp e22916- (2023)

O-GlcNAcylation is a post-translational modification of proteins that regulates various biological processes. However, its involvement in peritoneal dialysis fibrosis remains unclear. This study aimed to investigate the impact of O-GlcNAcylation on h

Externí odkaz: https://doaj.org/article/b19bc5945de8453a882ad76d30be2c08

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