Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Ashan Musafer"'
Autor:
Elizabeth M. Swisher, Tanya T. Kwan, Amit M. Oza, Anna V. Tinker, Isabelle Ray-Coquard, Ana Oaknin, Robert L. Coleman, Carol Aghajanian, Gottfried E. Konecny, David M. O’Malley, Alexandra Leary, Diane Provencher, Stephen Welch, Lee-may Chen, Andrea E. Wahner Hendrickson, Ling Ma, Prafull Ghatage, Rebecca S. Kristeleit, Oliver Dorigo, Ashan Musafer, Scott H. Kaufmann, Julia A. Elvin, Douglas I. Lin, Setsuko K. Chambers, Erin Dominy, Lan-Thanh Vo, Sandra Goble, Lara Maloney, Heidi Giordano, Thomas Harding, Alexander Dobrovic, Clare L. Scott, Kevin K. Lin, Iain A. McNeish
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
The identification of biomarkers of response to PARP inhibitors can enable selection of appropriate ovarian cancer patients for treatment. In this study, the authors report clinical results and exploratory biomarker analyses from the ARIEL2 phase 2 c
Externí odkaz:
https://doaj.org/article/4c0bb318d2464bacb5fcd01f6ceefda3
Autor:
Sagun Parakh, Ashan Musafer, Sabrina Paessler, Tom Witkowski, Connie S. N. Li Wai Suen, Candani S. A. Tutuka, Matteo S. Carlino, Alexander M. Menzies, Richard A. Scolyer, Jonathan Cebon, Alexander Dobrovic, Georgina V. Long, Oliver Klein, Andreas Behren
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
A significant number of patients (pts) with metastatic melanoma do not respond to anti-programmed cell death 1 (PD1) therapies. Identifying predictive biomarkers therefore remains an urgent need. We retrospectively analyzed plasma DNA of pts with adv
Externí odkaz:
https://doaj.org/article/60fdb249cd3241e8afe688013434c093
Autor:
Clare L. Scott, Matthew J. Wakefield, Alexander Dobrovic, Scott H. Kaufmann, Nicola Waddell, Katia Nones, S. John Weroha, Elizabeth M. Swisher, David D.L. Bowtell, Anna DeFazio, Australian Ovarian Cancer Study, Nadia Traficante, Orla McNally, Inger Olesen, Damien Kee, Maria I. Harrell, Mohammad Reza Eftekhariyan Ghamsari, Zi Qing Chai, Ashan Musafer, Marc Radke, Kristy Shield-Artin, Nirashaa Bound, Genevieve Dall, Elizabeth Lieschke, Gwo-Yaw Ho, Cassandra J. Vandenberg, Cordelia D. McGehee, Rachel M. Hurley, Olga Kondrashova, Ksenija Nesic
In high-grade serous ovarian carcinoma (HGSC), deleterious mutations in DNA repair gene RAD51C are established drivers of defective homologous recombination and are emerging biomarkers of PARP inhibitor (PARPi) sensitivity. RAD51C promoter methylatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e56ea8d4ae85dde3e5f8a4e6285a8fd
https://doi.org/10.1158/0008-5472.c.6513498
https://doi.org/10.1158/0008-5472.c.6513498
Autor:
Clare L. Scott, Matthew J. Wakefield, Alexander Dobrovic, Scott H. Kaufmann, Nicola Waddell, Katia Nones, S. John Weroha, Elizabeth M. Swisher, David D.L. Bowtell, Anna DeFazio, Australian Ovarian Cancer Study, Nadia Traficante, Orla McNally, Inger Olesen, Damien Kee, Maria I. Harrell, Mohammad Reza Eftekhariyan Ghamsari, Zi Qing Chai, Ashan Musafer, Marc Radke, Kristy Shield-Artin, Nirashaa Bound, Genevieve Dall, Elizabeth Lieschke, Gwo-Yaw Ho, Cassandra J. Vandenberg, Cordelia D. McGehee, Rachel M. Hurley, Olga Kondrashova, Ksenija Nesic
All Supplementary Methods for the manuscript
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72057a47e3c29c834e15f851c84579c8
https://doi.org/10.1158/0008-5472.22429956
https://doi.org/10.1158/0008-5472.22429956
Autor:
Clare L. Scott, Matthew J. Wakefield, Alexander Dobrovic, Scott H. Kaufmann, Nicola Waddell, Katia Nones, S. John Weroha, Elizabeth M. Swisher, David D.L. Bowtell, Anna DeFazio, Australian Ovarian Cancer Study, Nadia Traficante, Orla McNally, Inger Olesen, Damien Kee, Maria I. Harrell, Mohammad Reza Eftekhariyan Ghamsari, Zi Qing Chai, Ashan Musafer, Marc Radke, Kristy Shield-Artin, Nirashaa Bound, Genevieve Dall, Elizabeth Lieschke, Gwo-Yaw Ho, Cassandra J. Vandenberg, Cordelia D. McGehee, Rachel M. Hurley, Olga Kondrashova, Ksenija Nesic
All supplementary tables for the manuscript
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9978f21b18492658a866a239188bd868
https://doi.org/10.1158/0008-5472.22429950
https://doi.org/10.1158/0008-5472.22429950
Autor:
Clare L. Scott, Matthew J. Wakefield, Alexander Dobrovic, Scott H. Kaufmann, Nicola Waddell, Katia Nones, S. John Weroha, Elizabeth M. Swisher, David D.L. Bowtell, Anna DeFazio, Australian Ovarian Cancer Study, Nadia Traficante, Orla McNally, Inger Olesen, Damien Kee, Maria I. Harrell, Mohammad Reza Eftekhariyan Ghamsari, Zi Qing Chai, Ashan Musafer, Marc Radke, Kristy Shield-Artin, Nirashaa Bound, Genevieve Dall, Elizabeth Lieschke, Gwo-Yaw Ho, Cassandra J. Vandenberg, Cordelia D. McGehee, Rachel M. Hurley, Olga Kondrashova, Ksenija Nesic
All supplementary figures for the manuscript
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64220fae7fa95d48dedecbd1398a6415
https://doi.org/10.1158/0008-5472.22429959
https://doi.org/10.1158/0008-5472.22429959
Autor:
Mohammad Reza Eftekhariyan Ghamsari, Nadia Traficante, Nirashaa Bound, Cordelia D. McGehee, Inger Olesen, Kristy Shield-Artin, Clare L. Scott, Elizabeth Lieschke, Rachel M. Hurley, Anna deFazio, Ashan Musafer, Nicola Waddell, Marc R. Radke, Matthew Wakefield, Alexander Dobrovic, Ksenija Nesic, Genevieve Dall, Maria I. Harrell, Olga Kondrashova, Damien Kee, S. John Weroha, Scott H. Kaufmann, Katia Nones, David D.L. Bowtell, Cassandra J. Vandenberg, Orla McNally, Elizabeth M. Swisher, Gwo-Yaw Ho, Zi Qing Chai
Publikováno v:
Cancer Research. 81:4709-4722
In high-grade serous ovarian carcinoma (HGSC), deleterious mutations in DNA repair gene RAD51C are established drivers of defective homologous recombination and are emerging biomarkers of PARP inhibitor (PARPi) sensitivity. RAD51C promoter methylatio
Autor:
Ling Ma, Tanya T. Kwan, Clare L. Scott, Isabelle Ray-Coquard, Ana Oaknin, Alexander Dobrovic, Robert L. Coleman, Iain A. McNeish, Andrea E. Wahner Hendrickson, Lee-may Chen, Alexandra Leary, Stephen Welch, Thomas Harding, Lara Maloney, Carol Aghajanian, Kevin K. Lin, Heidi Giordano, E. Dominy, Ashan Musafer, Gottfried E. Konecny, Scott H. Kaufmann, Diane Provencher, Julia A. Elvin, Oliver Dorigo, Sandra Goble, R Kristeleit, Douglas I. Lin, Anna V. Tinker, Amit M. Oza, Setsuko K. Chambers, David M. O'Malley, Elizabeth M. Swisher, Prafull Ghatage, Lan Thanh Vo
Publikováno v:
Nature Communications
Nature communications, vol 12, iss 1
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Scientia
Nature communications, vol 12, iss 1
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Scientia
ARIEL2 (NCT01891344) is a single-arm, open-label phase 2 study of the PARP inhibitor (PARPi) rucaparib in relapsed high-grade ovarian carcinoma. In this post hoc exploratory biomarker analysis of pre- and post-platinum ARIEL2 samples, RAD51C and RAD5
Autor:
Gareth Rivalland, Eddie Lau, Paul Mitchell, Alexander Dobrovic, Ashan Musafer, Zoe Loh, Surein Arulananda, Hongdo Do, Thomas John
Publikováno v:
Journal of Thoracic Disease. 11:1756-1764
Background: Leptomeningeal spread in non-small cell lung cancer (NSCLC) patients with epidermal growth factor receptor ( EGFR ) mutations who experience disease progression on TKIs portends a poor prognosis. Mutation profiling of tumour DNA in cerebr
Autor:
Ksenija, Nesic, Olga, Kondrashova, Rachel M, Hurley, Cordelia D, McGehee, Cassandra J, Vandenberg, Gwo-Yaw, Ho, Elizabeth, Lieschke, Genevieve, Dall, Nirashaa, Bound, Kristy, Shield-Artin, Marc, Radke, Ashan, Musafer, Zi Qing, Chai, Mohammad Reza Eftekhariyan, Ghamsari, Maria I, Harrell, Damien, Kee, Inger, Olesen, Orla, McNally, Nadia, Traficante, Australian Ovarian Cancer Study, Anna, DeFazio, David D L, Bowtell, Elizabeth M, Swisher, S John, Weroha, Katia, Nones, Nicola, Waddell, Scott H, Kaufmann, Alexander, Dobrovic, Matthew J, Wakefield, Clare L, Scott
Publikováno v:
Cancer research. 81(18)
In high-grade serous ovarian carcinoma (HGSC), deleterious mutations in DNA repair gene