Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Asha Padar"'
Autor:
John D. Minna, Prakash Makarla, Victor Stastny, Lin Li, Ziding Feng, Makoto Suzuki, Kuntal Majmudar, Adi F. Gazdar, Ubaradka G. Sathyanarayana, Angela Yen Moore, Asha Padar
Publikováno v:
Cancer letters. 432
Autor:
Ziding Feng, Adi F. Gazdar, John D. Minna, Lin Li, Kuntal Majmudar, Prakash Makarla, Victor Stastny, Ubaradka G. Sathyanarayana, Angela Yen Moore, Asha Padar, Makoto Suzuki
Publikováno v:
Cancer Letters. 245:112-120
We investigated the aberrant promoter methylation status of 12 genes in skin lesions, both malignant (basal cell carcinomas (BCCs), n=68 and squamous cell carcinomas (SCCs), n=35) and non-malignant (tags, n=58) skin lesions and compared the results o
Autor:
Asha Padar, Adi F. Gazdar, Arthur I. Sagalowsky, Bogdan Czerniak, H. Barton Grossman, Ubaradka G. Sathyanarayana, Jolanta Bondaruk, Makoto Suzuki, John D. Minna, Eugene P. Frenkel, Riichiroh Maruyama
Publikováno v:
Cancer Research. 64:1425-1430
Laminin-5 (LN5) anchors epithelial cells to the underlying basement membrane, and it is encoded by three distinct genes: LAMA3, LAMB3, and LAMC2. To metastasize and grow, cancer cells must invade and destroy the basement membrane. Our previous work h
Autor:
Ubaradka G, Sathyanarayana, Angela Yen, Moore, Lin, Li, Asha, Padar, Kuntal, Majmudar, Victor, Stastny, Prakash, Makarla, Makoto, Suzuki, John D, Minna, Ziding, Feng, Adi F, Gazdar
Publikováno v:
Cancer letters. 245(1-2)
We investigated the aberrant promoter methylation status of 12 genes in skin lesions, both malignant (basal cell carcinomas (BCCs), n=68 and squamous cell carcinomas (SCCs), n=35) and non-malignant (tags, n=58) skin lesions and compared the results o
Autor:
Ubaradka G, Sathyanarayana, Asha, Padar, Makoto, Suzuki, Riichiroh, Maruyama, Hisayuki, Shigematsu, Jer-Tsong, Hsieh, Eugene P, Frenkel, Adi F, Gazdar
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 9(17)
Laminin-5 (LN5) is an essential component of the basement membrane (BM) and is composed of three chains that are the products of three distinct genes (LAMA3, LAMB3, and LAMC2). Differential expression of LN5 genes has been reported in prostate and ot
Autor:
Ubaradka G, Sathyanarayana, Asha, Padar, Chun Xian, Huang, Makoto, Suzuki, Hisayuki, Shigematsu, B Nebiyou, Bekele, Adi F, Gazdar
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 9(17)
Down-regulation of Laminin-5 (LN5)-encoding genes (LAMA3, LAMB3, and LAMC2) has been reported in various human cancers. However, the mechanism of inactivation was not clearly understood until recently. In this study, we investigated the loss of expre
Autor:
Asha, Padar, Ubaradka G, Sathyanarayana, Makoto, Suzuki, Riichiroh, Maruyama, Jer-Tsong, Hsieh, Eugene P, Frenkel, John D, Minna, Adi F, Gazdar
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 9(13)
Loss or abnormal expression of Cyclin D2, a crucial cell cycle-regulatory gene, has been described in human cancers; however, data for prostate tumors are lacking. We investigated the epigenetic silencing of Cyclin D2 gene in prostate cancers and cor
Autor:
Ubaradka G, Sathyanarayana, Makoto, Suzuki, Shinichi, Toyooka, Asha, Padar, Kiyomi O, Toyooka, Andrea L, Zern, Kuniharu, Miyajima, Takashi, Takahashi, Elizabeth, Brambilla, Adi F, Gazdar
Publikováno v:
Cancer genomicsproteomics. 1(1)
14-3-3σ gene has been shown to be responsible for G2 cell cycle checkpoint control by p53 in response to DNA damage in human cells. In order to increase the potential utility of 14-3-3σ gene as a molecular marker in tumor analysis and prognosis, we
Autor:
Ubaradka G, Sathyanarayana, Shinichi, Toyooka, Asha, Padar, Takashi, Takahashi, Elizabeth, Brambilla, John D, Minna, Adi F, Gazdar
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 9(7)
We investigated the loss of expression of three laminin-5 (LN5)-encoding genes in lung cancer cell lines and elucidated the mechanism of inactivation of the genes in lung cancer cell lines and tumors.We examined the expression of LN5-encoding genes b
Autor:
Asha Rathi, Jack A. Roth, Kenji Sugio, Takashi Takahashi, Frank C. Kischel, Adi F. Gazdar, David M. Euhus, Ubaradka G. Sathyanarayana, John D. Minna, Shinichi Toyooka, Arvind K. Virmani, Vijay S. Tonk, Asha Padar
Publikováno v:
International journal of cancer. 106(2)
TMS1 (target of methylation-induced silencing) is a CpG island-associated gene that functions in the regulation of apoptosis and encodes a caspase recruitment domain, a recently described motif found in apoptotic signaling molecules. Recent evidence