Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Asha Nayak-Kapoor"'
Autor:
Chunwan Lu, John D. Klement, Mohammed L. Ibrahim, Wei Xiao, Priscilla S. Redd, Asha Nayak-Kapoor, Gang Zhou, Kebin Liu
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-11 (2019)
Abstract Background Type I interferons (IFN-I) have recently emerged as key regulators of tumor response to chemotherapy and immunotherapy. However, IFN-I function in cytotoxic T lymphocytes (CTLs) in the tumor microenvironment is largely unknown. Me
Externí odkaz:
https://doaj.org/article/e8053858e6cf4ada8cc8d9e9154227a4
Autor:
Alyssa D. Merting, Dakota B. Poschel, Chunwan Lu, John D. Klement, Dafeng Yang, Honglin Li, Huidong Shi, Eric Chapdelaine, Mitzi Montgomery, Michael T. Redman, Natasha M. Savage, Asha Nayak-Kapoor, Kebin Liu
Publikováno v:
Cancers, Vol 14, Iss 2, p 361 (2022)
A hallmark of human colorectal cancer is lost expression of FAS, the death receptor for FASL of cytotoxic T lymphocytes (CTLs). However, it is unknown whether restoring FAS expression alone is sufficient to suppress csolorectal-cancer development. Th
Externí odkaz:
https://doaj.org/article/d7f5d7edcbaf4f48af54f4587ad62730
Autor:
Asha Nayak-Kapoor, Zhonglin Hao, Ramses Sadek, Robin Dobbins, Lisa Marshall, Nicholas N. Vahanian, W. Jay Ramsey, Eugene Kennedy, Mario R. Mautino, Charles J. Link, Ray S. Lin, Stephanie Royer-Joo, Xiaorong Liang, Laurent Salphati, Kari M. Morrissey, Sami Mahrus, Bruce McCall, Andrea Pirzkall, David H. Munn, John E. Janik, Samir N. Khleif
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 6, Iss 1, Pp 1-12 (2018)
Abstract Background Indoleamine-2,3-dioxygenase 1 (IDO1) catalyzes the oxidation of tryptophan into kynurenine and is partially responsible for acquired immune tolerance associated with cancer. The IDO1 small molecule inhibitor navoximod (GDC-0919, N
Externí odkaz:
https://doaj.org/article/fa3f41ad888d41f5a1c759f8b6fa21b2
Autor:
Kebin Liu, Asha Nayak-Kapoor, Dafeng Yang, Amy V. Paschall, Sarah K. Sharman, John D. Klement, Mohammed L. Ibrahim, Priscilla S. Redd
Figure S1 shows MDSC profiles in chaetocin-treated tumor-bearing mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47924fe511aa5b18f6235b7599fe5f27
https://doi.org/10.1158/0008-5472.22413720
https://doi.org/10.1158/0008-5472.22413720
Autor:
Kebin Liu, Asha Nayak-Kapoor, Dafeng Yang, Amy V. Paschall, Sarah K. Sharman, John D. Klement, Mohammed L. Ibrahim, Priscilla S. Redd
Table S1 contains oligonucleotide sequences
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83e62b621a777213560e40b75edf37c7
https://doi.org/10.1158/0008-5472.22413714.v1
https://doi.org/10.1158/0008-5472.22413714.v1
Autor:
Kebin Liu, Asha Nayak-Kapoor, Thomas J. Hartney, Huidong Shi, Zhuoqi Liu, Qimei Han, Dafeng Yang, Mohammed L. Ibrahim, Priscilla S. Redd, John D. Klement, Amy V. Paschall, Daniela Payne, Chunwan Lu, Alyssa D. Smith
Although accumulation of myeloid-derived suppressor cells (MDSC) is a hallmark of cancer, the underlying mechanism of this accumulation within the tumor microenvironment remains incompletely understood. We report here that TNFα–RIP1–mediated nec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::732e561085fd8a7fabf8263cf20c22c0
https://doi.org/10.1158/0008-5472.c.6511563.v1
https://doi.org/10.1158/0008-5472.c.6511563.v1
Autor:
David S. Hong, Margaret A. Marshall, Floyd E. Fox, Agron Collaku, Mario Sznol, Solmaz Sahebjam, Asha Nayak-Kapoor, Omid Hamid, Dmitriy Zamarin
Purpose:The study goal was to determine safety, antitumor activity, and pharmacodynamic profile of mogamulizumab, an anti–C-C chemokine receptor 4 (anti-CCR4) mAb targeting effector regulatory T cells (eTreg), in combination with mAb checkpoint inh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::789dd51a836fd401e6299f0176a6fb9d
https://doi.org/10.1158/1078-0432.c.6529641.v1
https://doi.org/10.1158/1078-0432.c.6529641.v1
Autor:
Kebin Liu, Asha Nayak-Kapoor, Dafeng Yang, Amy V. Paschall, Sarah K. Sharman, John D. Klement, Mohammed L. Ibrahim, Priscilla S. Redd
marked manuscript for review only
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43ab149835a33855e4ffc3cd898c8232
https://doi.org/10.1158/0008-5472.22413723.v1
https://doi.org/10.1158/0008-5472.22413723.v1
Autor:
Kebin Liu, Asha Nayak-Kapoor, Dafeng Yang, Amy V. Paschall, Sarah K. Sharman, John D. Klement, Mohammed L. Ibrahim, Priscilla S. Redd
Inducible nitric oxide synthase (iNOS) generates nitric oxide (NO) in myeloid cells that acts as a defense mechanism to suppress invading microorganisms or neoplastic cells. In tumor-bearing mice, elevated iNOS expression is a hallmark of myeloid-der
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7ad0d1238ac61cf9a3db81d4dc9afd3
https://doi.org/10.1158/0008-5472.c.6508797.v1
https://doi.org/10.1158/0008-5472.c.6508797.v1
Autor:
Kebin Liu, Asha Nayak-Kapoor, Thomas J. Hartney, Huidong Shi, Zhuoqi Liu, Qimei Han, Dafeng Yang, Mohammed L. Ibrahim, Priscilla S. Redd, John D. Klement, Amy V. Paschall, Daniela Payne, Chunwan Lu, Alyssa D. Smith
Supplemental Figures 1-7. Figure S1. IRF8 expression profiles in subsets of immune cells in spleens of tumor-bearing mice. Figure S2. IRF8 expression profiles in subsets of immune cells in peripheral blood of tumor-bearing mice. Figure S3. DNA methyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3869f6df0af884ee5f4811e50c38c9e4
https://doi.org/10.1158/0008-5472.22423710.v1
https://doi.org/10.1158/0008-5472.22423710.v1