Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Asha Dopplapudi"'
Autor:
M. Paula M. Marques, Ana L. M. Batista de Carvalho, Adriana P. Mamede, Asha Dopplapudi, Svemir Rudić, Madhusudan Tyagi, Victoria Garcia Sakai, Luís A. E. Batista de Carvalho
Publikováno v:
Molecules, Vol 25, Iss 2, p 246 (2020)
The mode of action of Pt- and Pd-based anticancer agents (cisplatin and Pd2Spm) was studied by characterising their impact on DNA. Changes in conformation and mobility at the molecular level in hydrated DNA were analysed by quasi-elastic and inelasti
Externí odkaz:
https://doaj.org/article/791f4e36fb65467ba518d62414516316
Autor:
Nick Warr, Debora Bogani, Pam Siggers, Rachel Brixey, Hilda Tateossian, Asha Dopplapudi, Sara Wells, Michael Cheeseman, Ying Xia, Harry Ostrer, Andy Greenfield
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e19572 (2011)
In mammals, the Y chromosome is a dominant male determinant, causing the bipotential gonad to develop as a testis. Recently, cases of familial and spontaneous 46,XY disorders of sex development (DSD) have been attributed to mutations in the human gen
Externí odkaz:
https://doaj.org/article/90c4c456a12b4bcdaab8107f57443116
Autor:
Asha Dopplapudi, Maria Paula M. Marques, L. A. E. Batista de Carvalho, A. L. M. Batista de Carvalho, V. García Sakai, Svemir Rudić, A. P. Mamede
Publikováno v:
International Reviews in Physical Chemistry. 39:67-81
Water is the major constituent of the human body and plays a vital role in biochemical processes. Even subtle variations in the structure or dynamics of intracellular water may be the driving force...
Autor:
Gianfelice Cinque, Peter Gardner, Victoria García Sakai, I. Santos, Asha Dopplapudi, Ana L. M. Batista de Carvalho, Luís A. E. Batista de Carvalho, A. P. Mamede, Magda Wolna, Maria Paula M. Marques
Publikováno v:
The Journal of Physical Chemistry B. 123:6968-6979
This study aimed at the development of improved drugs against human osteosarcoma, which is the most common primary bone tumor in children and teenagers with a low prognosis. New insights into the impact of an unconventional Pd(II) anticancer agent on
Autor:
Gianfelice Cinque, M. Paula M. Marques, Ana L. M. Batista de Carvalho, A. P. Mamede, James Doherty, Mark D. Frogley, Luís A. E. Batista de Carvalho, Victoria García Sakai, Diego Gianolio, Asha Dopplapudi, Peter Gardner
Publikováno v:
Batista de Carvalho, A, Mamede, A, Dopplapudi, A, Garcia Sakai, V, Doherty, J, Frogley, M, Cinque, G, Gardner, P, Gianolio, D, Batista de Carvalho, L & Marques, M 2019, ' Anticancer Drug Impact on DNA – A Study by Neutron Spectroscopy coupled to Synchrotron-based FTIR and EXAFS ', Physical Chemistry Chemical Physics: high quality research in physical chemistry, chemical physics and biophysical chemistry, vol. 21, no. 8, pp. 4162-4175 . https://doi.org/10.1039/C8CP05881D, https://doi.org/10.1039/c8cp05881d
Batista De Carvalho, A L M, Mamede, A P, Dopplapudi, A, Garcia Sakai, V, Doherty, J, Frogley, M, Cinque, G, Gardner, P, Gianolio, D, Batista De Carvalho, L A E & Marques, M P M 2019, ' Anticancer drug impact on DNA – a study by neutron spectroscopy coupled with synchrotron-based FTIR and EXAFS ', Physical Chemistry Chemical Physics, vol. 21, no. 8, pp. 4162-4175 . https://doi.org/10.1039/c8cp05881d
Batista De Carvalho, A L M, Mamede, A P, Dopplapudi, A, Garcia Sakai, V, Doherty, J, Frogley, M, Cinque, G, Gardner, P, Gianolio, D, Batista De Carvalho, L A E & Marques, M P M 2019, ' Anticancer drug impact on DNA – a study by neutron spectroscopy coupled with synchrotron-based FTIR and EXAFS ', Physical Chemistry Chemical Physics, vol. 21, no. 8, pp. 4162-4175 . https://doi.org/10.1039/c8cp05881d
Complementary structural and dynamical information on drug-DNA interplay has been achieved at a molecular level, for Pt/Pd-drugs, allowing a better understanding of their pharmacodynamic profile which is crucial for the development of improved chemot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::298c1eb7890c112cccb271fa3f3fd769
http://www.scopus.com/inward/record.url?scp=85061869063&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=85061869063&partnerID=8YFLogxK
Autor:
A. L. M. Batista de Carvalho, L. A. E. Batista de Carvalho, Maria Paula M. Marques, Asha Dopplapudi, A. P. Mamede, V. García Sakai
Publikováno v:
Structural Dynamics, Vol 7, Iss 5, Pp 054701-054701-9 (2020)
Structural Dynamics
Structural Dynamics
The transition from normal to malignant state in human cells is still a poorly understood process. Changes in the dynamical activity of intracellular water between healthy and cancerous human cells were probed as an innovative approach for unveiling
Autor:
Gianfelice Cinque, Ana L. M. Batista de Carvalho, Adriana Pires Mamede, Victoria García Sakai, Peter Gardner, Asha Dopplapudi, Luís A. E. Batista de Carvalho, Diego Gianolio, M. Paula M. Marques, James J. Doherty, Mark D. Frogley
A complementary structural and dynamical information on drug-DNA interplay has been achieved at a molecular level, for Pt/Pd-drugs, allowing a better understanding of their pharmacodynamic profile. The interaction of two cisplatin-like dinuclear Pt(I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecb6dad963f68c124fe436e8f6741410
Autor:
Jihad Adnan, Tudor A. Fulga, Katharine J. Marler, Angélique Bordey, Andrew S. Lowe, Philipp Suetterlin, Uwe Drescher, Nicola A. Maiorano, David Van Vactor, Robert Hindges, Ian D. Thompson, Aine Rubikaite, Asha Dopplapudi, Manav Pathania
Publikováno v:
Marler, K J, Suetterlin, P, Dopplapudi, A, Rubikaite, A, Adnan, J, Maiorano, N A, Lowe, A S, Thompson, I D, Pathania, M, Bordey, A, Fulga, T, Van Vactor, D L, Hindges, R & Drescher, U 2014, ' BDNF promotes axon branching of retinal ganglion cells via miRNA-132 and p250GAP ', Journal of Neuroscience, vol. 34, no. 3, N/A, pp. 969 – 979 . https://doi.org/10.1523/JNEUROSCI.1910-13.2014
A crucial step in the development of the vertebrate visual system is the branching of retinal ganglion cell (RGC) axons within their target, the superior colliculus/tectum. A major player in this process is the neurotrophin brain-derived neurotrophic