Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Asha B. Pawagi"'
Publikováno v:
Biochemical and Biophysical Research Communications. 374:128-133
Muscarinic receptor extracted from porcine atria in digitonin-cholate copurified with Galpha(o), Galpha(i1-3), and caveolins. The presence of complexes was confirmed by coimmunoprecipitation of the receptor, alpha-subunits, and caveolins in various c
Publikováno v:
Biochemistry. 36:7361-7379
Cooperativity has been investigated as the mechanistic basis for effects observed with cardiac muscarinic receptors in washed membranes from Syrian hamsters. Specifically, N-[3H]methylscopolamine labeled only 66-75% of the sites labeled by [3H]quinuc
Publikováno v:
Journal of Molecular Biology. 235:554-564
Multidrug resistance (MDR) in cancer cells is associated with overexpression of P-glycoprotein (Pgp), a membrane protein which interacts with structurally diverse hydrophobic molecules of high membrane affinity. In an analysis of the molecular basis
Autor:
Asha B. Pawagi, Charles M. Deber
Publikováno v:
Biochemistry. 29:950-955
D-Glucose transport by the 492-residue human erythrocyte hexose transport protein may involve ligand-mediated conformational/positional changes. To examine this possibility, hydrophilic quencher molecules [potassium iodide and acrylamide (ACR)] were
Publikováno v:
Biochemistry. 41(17)
Muscarinic cholinergic receptors can appear to be more numerous when labeled by [(3)H]quinuclidinylbenzilate (QNB) than by N-[(3)H]methylscopolamine (NMS). The nature of the implied heterogeneity has been studied with M(2) receptors in detergent-solu
Autor:
Asha B. Pawagi, Ian M. Campbell
Publikováno v:
Canadian Journal of Biochemistry. 58:345-351
Campbell, I. M. & Pawagi, A. B. (1980) The effect of polypeptide-lipid interactions on the ultraviolet spectrum of the olefinic bonds of the lipid. Can. J. Biochem. 58, 345-351 The effect of associating acidic and basic polypeptides with dilute suspe
Publikováno v:
Canadian Journal of Biochemistry. 57:302-307
The permeability of synthetic phosphatidylcholines has been studied with stopped-flow spectrometry by monitoring the initial shrinkage or swelling velocity of the sonicated vesicles. It was observed that aqueous diffusion was more rapid through dilin
Autor:
Asha B. Pawagi, Ian M. Campbell
Publikováno v:
Canadian Journal of Biochemistry. 60:593-598
In earlier studies it was found that the association of basic polypeptides with lipid vesicles drastically altered ultraviolet absorption by the olefinic bonds of the lipid. Such an effect suggested that the polypeptide was increasing the polarity of
Autor:
Asha B. Pawagi, Ian M. Campbell
Publikováno v:
Canadian Journal of Biochemistry. 59:404-411
The results of electrical conductivity and ultraviolet absorption studies on bilayer vesicles, composed of various mixtures of saturated dipalmitoylphosphatidylcholine (DPPC) and unsaturated bovine brain phosphatidylserine (PS), in the presence and a
Autor:
Charles M. Deber, Asha B. Pawagi
Publikováno v:
Biochemical and biophysical research communications. 145(3)
Purified hexose transport protein (“band 4.5”) from human erythrocytes, reconstituted in vesicles of its endogenous lipids, displays minima in its circular dichroism (CD) spectrum at 222 and 207 nm, a pattern diagnostic for α-helical content of