Unveiling anti-diabetic potential of new thiazole-sulfonamide derivatives: Design, synthesis, in vitro bio-evaluation targeting DPP-4, α-glucosidase, and α-amylase with in-silico ADMET and docking simulation

Autor: Khamees Thabet, Hamdy, Ammar, Yousry A., Imran, Mohd, Hamdy Helal, Mohamed, Ibrahim Alaqel, Saleh, Alshehri, Ahmed, Ash Mohd, Abida, Abusaif, Moustafa S., Ragab, Ahmed

Publikováno v: In Bioorganic Chemistry October 2024 151

Innovation of 6-sulfonamide-2 H -chromene derivatives as antidiabetic agents targeting α-amylase, α-glycosidase, and PPAR-γ inhibitors with in silico molecular docking simulation.

Autor: Thabet HK; Department of Chemistry, College of Sciences and Arts, Northern Border University Rafha 91911 Saudi Arabia Hamdy.salem@nbu.edu.sa., Ragab A; Department of Chemistry, Faculty of Science (Boys), Al-Azhar University Nasr City 11884 Cairo Egypt ahmed_ragab@azhar.edu.eg Ahmed_ragab7@ymail.com., Imran M; Department of Pharmaceutical Chemistry, College of Pharmacy, Northern Border University Rafha 91911 Saudi Arabia., Hamdy Helal M; Department of Chemistry, College of Sciences and Arts, Northern Border University Rafha 91911 Saudi Arabia Hamdy.salem@nbu.edu.sa., Ibrahim Alaqel S; Department of Pharmaceutical Chemistry, College of Pharmacy, Northern Border University Rafha 91911 Saudi Arabia., Alshehri A; Department of Pharmacology and Toxicology, College of Pharmacy, Northern Border University Rafha 91911 Saudi Arabia.; Department of Pharmacology, College of Clinical Pharmacy, Imam Abdulrahman Bin Faisal University King Faisal Road Dammam 31441 Saudi Arabia., Ash Mohd A; Department of Pharmaceutical Chemistry, College of Pharmacy, Northern Border University Rafha 91911 Saudi Arabia., Alshammari SS; Department of Chemistry, College of Sciences and Arts, Northern Border University Rafha 91911 Saudi Arabia Hamdy.salem@nbu.edu.sa., Ammar YA; Department of Chemistry, Faculty of Science (Boys), Al-Azhar University Nasr City 11884 Cairo Egypt ahmed_ragab@azhar.edu.eg Ahmed_ragab7@ymail.com., Abusaif MS; Department of Chemistry, Faculty of Science (Boys), Al-Azhar University Nasr City 11884 Cairo Egypt ahmed_ragab@azhar.edu.eg Ahmed_ragab7@ymail.com.

Publikováno v: RSC advances [RSC Adv] 2024 May 14; Vol. 14 (22), pp. 15691-15705. Date of Electronic Publication: 2024 May 14 (Print Publication: 2024).

Innovation of 6-sulfonamide-2H-chromene derivatives as antidiabetic agents targeting α-amylase, α-glycosidase, and PPAR-γ inhibitors with in silico molecular docking simulation.

Autor: Thabet, Hamdy Khamees, Ragab, Ahmed, Imran, Mohd, Helal, Mohamed Hamdy, Alaqel, Saleh Ibrahim, Alshehri, Ahmed, Mohd, Abida Ash, Alshammari, Saleh Saad, Ammar, Yousry A., Abusaif, Moustafa S.

Publikováno v: RSC Advances; 2024, Vol. 14 Issue 22, p15691-15705, 15p

INCREASING SECURITY AWARENESS THROUGH LENSES OF CYBERSECURITY CULTURE.

Autor: ANDRONACHE, Alina^1,2 alina.andronache@partner.uws.ac.uk

Publikováno v: Journal of Information Systems & Operations Management. Jul2021, Vol. 15 Issue 1, p7-22. 16p.

Improving employees' intellectual capacity for cybersecurity through evidence-based malware training.

Autor: He, Wu, Ash, Ivan, Anwar, Mohd, Li, Ling, Yuan, Xiaohong, Xu, Li, Tian, Xin

Publikováno v: Journal of Intellectual Capital; 2020, Vol. 21 Issue 2, p203-213, 11p