Zobrazeno 1 - 10
of 288
pro vyhledávání: '"Asgerally T Fazleabas"'
Autor:
Tae Hoon Kim, Jung-Yoon Yoo, Zhong Wang, John P Lydon, Shikha Khatri, Shannon M Hawkins, Richard E Leach, Asgerally T Fazleabas, Steven L Young, Bruce A Lessey, Bon Jeong Ku, Jae-Wook Jeong
Publikováno v:
PLoS Genetics, Vol 11, Iss 9, p e1005537 (2015)
AT-rich interactive domain 1A gene (ARID1A) loss is a frequent event in endometriosis-associated ovarian carcinomas. Endometriosis is a disease in which tissue that normally grows inside the uterus grows outside the uterus, and 50% of women with endo
Externí odkaz:
https://doaj.org/article/7b5adaf9c8a143f5b95b44b41b190596
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0125627 (2015)
IL-6 is a multifunctional pro-inflammatory cytokine and has been implicated in many gestational disorders including preterm birth. Currently, there are no appropriate therapeutic interventions available to circumvent inflammatory-mediated gestational
Externí odkaz:
https://doaj.org/article/af67df762e2f4cb4895a0b90e0006224
Autor:
Jung-Yoon Yoo, Heesung Shin, Tae Hoon Kim, Won-Seok Choi, Susan D Ferguson, Asgerally T Fazleabas, Steven L Young, Bruce A Lessey, Un-Hwan Ha, Jae-Wook Jeong
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e100481 (2014)
Endometriosis, defined as the presence of endometrial cells outside of the uterine cavity, is a major cause of infertility and pelvic pain, afflicting more than 10% of reproductive age women. Endometriosis is a chronic inflammatory disease and lipopo
Externí odkaz:
https://doaj.org/article/b26eabcd43524eadbcd8132890b7fb7d
Autor:
Chae Hyun Lee, Tae Hoon Kim, Jae Hee Lee, Seo Jin Oh, Jung-Yoon Yoo, Hyo Suk Kwon, Young Im Kim, Susan D Ferguson, Ji Yeon Ahn, Bon Jeong Ku, Asgerally T Fazleabas, Jeong Mook Lim, Jae-Wook Jeong
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e75282 (2013)
Decidualization is a crucial change required for successful embryo implantation and the maintenance of pregnancy. During this process, endometrial stromal cells differentiate into decidual cells in response to the ovarian steroid hormones of early pr
Externí odkaz:
https://doaj.org/article/fc31c7ca35964940af1805b333c07eef
Autor:
Jake J. Reske, Mike R. Wilson, Brooke Armistead, Shannon Harkins, Cristina Perez, Joel Hrit, Marie Adams, Scott B. Rothbart, Stacey A. Missmer, Asgerally T. Fazleabas, Ronald L. Chandler
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-26 (2022)
Abstract Background SWI/SNF (BAF) chromatin remodeling complexes regulate lineage-specific enhancer activity by promoting accessibility for diverse DNA-binding factors and chromatin regulators. Additionally, they are known to modulate the function of
Externí odkaz:
https://doaj.org/article/ee04432bf9b94d2b8a24e167638717a0
Autor:
Yong Song, Gregory W. Burns, Niraj R. Joshi, Ripla Arora, J. Julie Kim, Asgerally T. Fazleabas
Publikováno v:
JCI Insight, Vol 8, Iss 11 (2023)
The development and progression of endometriotic lesions are poorly understood, but immune cell dysfunction and inflammation are closely associated with the pathophysiology of endometriosis. There is a need for 3D in vitro models to permit the study
Externí odkaz:
https://doaj.org/article/2339a6f66a0d4f61826f230631e74f5f
Autor:
Jung-Yoon Yoo, Tae Hoon Kim, Jung-Ho Shin, Ryan M. Marquardt, Ulrich Müller, Asgerally T. Fazleabas, Steven L. Young, Bruce A. Lessey, Ho-Geun Yoon, Jae-Wook Jeong
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Female subfertility is highly associated with endometriosis. Here the authors show that progesterone-induced MIG-6 is reduced in endometrium of infertile women and non-human primates with endometriosis, and in a mouse model find that Erbb2 is the key
Externí odkaz:
https://doaj.org/article/e6ab3ae470b54ec4bb3069af1fbe2756
Autor:
Qiong Sha, Zach Madaj, Sarah Keaton, Martha L Escobar Galvis, LeAnn Smart, Stanislaw Krzyzanowski, Asgerally T. Fazleabas, Richard Leach, Teodor T. Postolache, Eric D. Achtyes, Lena Brundin
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract Depression during and after pregnancy affects up to 20% of pregnant women, but the biological underpinnings remain incompletely understood. As pregnancy progresses, the immune system changes to facilitate fetal development, leading to distin
Externí odkaz:
https://doaj.org/article/5361560700f1439a904d8c6cdd06329d
Autor:
Mike R. Wilson, Jake J. Reske, Jeanne Holladay, Genna E. Wilber, Mary Rhodes, Julie Koeman, Marie Adams, Ben Johnson, Ren-Wei Su, Niraj R. Joshi, Amanda L. Patterson, Hui Shen, Richard E. Leach, Jose M. Teixeira, Asgerally T. Fazleabas, Ronald L. Chandler
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-18 (2019)
PIK3CA mutations and ARID1A loss co-exist in endometrial neoplasms. Here, the authors show that these co-mutations drive gene expression profiles correlated with differential chromatin accessibility and ARID1A binding in the endometrial epithelium, r
Externí odkaz:
https://doaj.org/article/266dcb657cd34fc29c11bd4ed2e4f504
Autor:
Josephine A. Drury, Kirstin L. Parkin, Lucy Coyne, Emma Giuliani, Asgerally T. Fazleabas, Dharani K. Hapangama
Publikováno v:
Reproductive Biology and Endocrinology, Vol 16, Iss 1, Pp 1-11 (2018)
Abstract Background Endometriosis is a common condition associated with growth of endometrial-like tissue beyond the uterine cavity. Previous reports have suggested a role for uNK cells in the pathogenesis of endometriosis postulating that survival a
Externí odkaz:
https://doaj.org/article/1b74fa5cf27a42818d52fd44ab1f6569