Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Asger B. Petersen"'
Publikováno v:
Petersen, A B, Rønnest, M H, Larsen, T O & Clausen, M H 2014, ' The Chemistry of Griseofulvin ', Chemical Reviews, vol. 114, no. 24, pp. 12088-12107 . https://doi.org/10.1021/cr400368e
Specific synthetic routes are presented in schemes to illustrate the chemistry, and the analogs are presented in a table format to give an accessible overview of the structures. Several patents have been published regarding the properties of griseofu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61afa7eb4e18a9e5e5a1a7b08f42d7d0
https://doi.org/10.1021/cr400368e
https://doi.org/10.1021/cr400368e
Autor:
Mads Hartvig Clausen, Alwin Krämer, Marc S. Raab, Nur Hafzan Md Hanafiah, Asger B. Petersen, Peter Hammershøj, Gleb Konotop
Publikováno v:
Petersen, A B, Konotop, G, Hanafiah, N H M, Hammershøj, P, Raab, M S, Kraemer, A & Clausen, M H 2016, ' Strategies for improving the solubility and metabolic stability of griseofulvin analogues ', European Journal of Medicinal Chemistry, vol. 116, pp. 210-215 . https://doi.org/10.1016/j.ejmech.2016.03.071
We report two types of modifications to the natural product griseofulvin as strategies to improve solubility and metabolic stability: the conversion of aryl methyl ethers into aryl difluoromethyl ethers at metabolic hotspots and the conversion of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::768abadacc5ddce9d1ebbed0b25aac9f
https://orbit.dtu.dk/en/publications/40604233-593d-40af-be45-86a2e096e319
https://orbit.dtu.dk/en/publications/40604233-593d-40af-be45-86a2e096e319
Autor:
Thomas Bjørnholm, Kasper Moth-Poulsen, Mikael Bols, Titoo Jain, Erling Thyrhaug, Asger B. Petersen, Niels Harrit, Kristine Kilsaa
Publikováno v:
The Journal of Physical Chemistry B. 114:11771-11777
We present a strategy for chemical preparation of multiple copies of single-molecule electronic devices that is based on chemical self-assembly under equilibrium conditions in aqueous solution. As a first step in the realization of this, we show that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d62c1501bfdbebc983118770bca1a65c
https://doi.org/10.1021/jp105948v
https://doi.org/10.1021/jp105948v
Publikováno v:
ChemInform. 46
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87ac92a2124875355deda96bf0cfd1fc
https://doi.org/10.1002/chin.201510324
https://doi.org/10.1002/chin.201510324
Pseudo-complementary oligonucleotide analogues and mimics provide novel opportunities for targeting duplex structures in RNA and DNA. Previously, a pseudo-complementary A-T base pair has been introduced. Towards sequence unrestricted targeting, a pse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c18f7ba3121283d1cdef0569d7898a7
https://europepmc.org/articles/PMC3116581/
https://europepmc.org/articles/PMC3116581/
Autor:
Jérôme Cornil, Jeppe Fock, Anders Holmen Pedersen, Karsten Jennum, Mogens Brøndsted Nielsen, Klaus Bechgaard, Asger B. Petersen, Jakob Kryger Sørensen, Victor Geskin, Thomas Bjørnholm, Kristine Kilså
Publikováno v:
The Journal of organic chemistry. 76(1)
In continuation of previous studies showing promising metal-molecule contact properties a variety of C(60) end-capped "molecular wires" for molecular electronics were prepared by variants of the Prato 1,3-dipolar cycloaddition reaction. Either benzen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45a53b5106f9d3a570a10823a0b1b8c2
https://pubmed.ncbi.nlm.nih.gov/21133403
https://pubmed.ncbi.nlm.nih.gov/21133403
Publikováno v:
ChemInform. 35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ee639385ec2285c73bbb4bf7047aed4
https://doi.org/10.1002/chin.200404178
https://doi.org/10.1002/chin.200404178
Autor:
Asger B. Petersen, Otto Dahl, Ulla Henriksen, Brian M. Nielsen, Britta M. Dahl, Daniel Sejer Pedersen, Jacob Wagner Jensen, Thomas Boesen, Michael T. Munck
Publikováno v:
ChemInform. 35
Preparation of the nucleoside analogues 1 and incorporation of 1, B = T, in deoxyribooligonucleotides by the phosphoramidite method is described. A two-step deprotection procedure was developed to reduce cleavage of the modified allylic unit. The bin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0ae2e7fb4d150b0cf23dff8d5604f60
https://doi.org/10.1002/chin.200402218
https://doi.org/10.1002/chin.200402218
Publikováno v:
Organicbiomolecular chemistry. 1(19)
The conformations of an acyclic, achiral enamide thymidine analogue 1 have been studied by model building and geometry calculations, as well as by NMR NOE and UV experiments. The results indicate that there are no significant barriers to rotation aro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::278268b3ec931aa795f7d625acddbae9
https://pubmed.ncbi.nlm.nih.gov/14584792
https://pubmed.ncbi.nlm.nih.gov/14584792
Publikováno v:
Nucleosides, nucleotidesnucleic acids. 22(5-8)
The new monomer 1 seems to be an excellent mimic of nucleosides with different sugar conformations (north, south, and envelope), because of the relatively free rotation around gamma, delta, and chi. The rotation around chi is primarily controlled by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05dd4ea9daad8178a636b2fa2aa60ecf
https://pubmed.ncbi.nlm.nih.gov/14565265
https://pubmed.ncbi.nlm.nih.gov/14565265