Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Asgar Electricwala"'
Autor:
Tony Atkinson, Asgar Electricwala
Publikováno v:
European Journal of Biochemistry. 147:511-516
Two epithelial plasminogen activators were purified from the serum-free conditioned medium of guinea pig keratocytes (GPK) and human breast epithelial (BEB) cells in culture. The cells were cultured on Cytodex 3 microcarrier beads in Eagles' minimum
Autor:
Jack Melling, Alan Doyle, Michael Dennis Scawen, Ian Stewart Small, Kearns Michael John, Anthony Atkinson, Asgar Electricwala, North John Robert, Patrick A. Riley, Peter Morgan Sutton, Griffiths John Bryan
Tissue plasminogen activator (tPA) derived from the non-cancerous mammalian cell line JMI-229 is found to have significantly greater binding affinity to human fibrin clots than currently available therapeutic-grade tPA, which is based on human tPA, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7cfb2ca1a150fd6ba597661bee4f7b01
https://doi.org/10.1016/b978-1-4377-1720-4.00571-9
https://doi.org/10.1016/b978-1-4377-1720-4.00571-9
Publikováno v:
Journal of Protein Chemistry. 12:365-370
Unlike the European leech Hirudo medicinalis, the Asian jawed leech Hirudinaria manillensis is specialized for feeding on mammalian blood. In the salivary glands of both these leeches, there is a potent inhibitor of thrombin, called hirudin, which ac
Autor:
Asgar Electricwala
Publikováno v:
Cytotechnology. 8:1-4
Publikováno v:
Fibrinolysis. 6:51-55
Mammalian cells are conventionally cultured in nutrient medium containing 10% foetal calf serum (FCS). The aim of the project was to investigate whether bovine milk extract could be used to replace or minimise the use of serum in cell culture without
Publikováno v:
Blood Coagulation & Fibrinolysis. 2:83-90
The leech Hirudinaria manillensis belongs to the same family as the medicinal leech Hirudo medicinalis, which has been widely used for the study of hirudin, a specific thrombin inhibitor. A similar inhibitor has now been isolated from the heads of th
Publikováno v:
Journal of enzyme inhibition. 6(4)
The jawed leech, Hirudinaria manillensis is closely related to Hirudo medicinalis, both belonging to the same family Arhynchobdellida. From Hirudo, two potent peptide inhibitors, hirudin (a thrombin inhibitor) and eglin (an elastase/chymotrypsin inhi
Autor:
Bryan Griffiths, Asgar Electricwala
Publikováno v:
Cell Biochemistry and Function. 4:55-60
The aim of this study was to investigate the possibility of enhancing the yield of tissue plasminogen activator (tPA) from two epithelial cell lines of normal (non-malignant) derivation grown in tissue culture. The three agents used in this investiga
Publikováno v:
Thrombosis and Haemostasis. 53:200-203
SummaryThe fibrinolytic and thrombolytic properties of a tissue plasminogen activator (tPA) purified from the conditioned medium of an established guinea pig keratocyte (GPK) cell line were investigated in in vitro systems and compared with urokinase
Autor:
Asgar Electricwala
Publikováno v:
Biochimica et biophysica acta. 990(1)
A simple and sensitive chromogenic microtitre plate assay for glycoprotein enzymes is described, using melanoma tissue plasminogen activator (t-PA) as a model enzyme. The assay is based on the binding of t-PA to immobilised lectin and quantitating th