Zobrazeno 1 - 10
of 320
pro vyhledávání: '"Asfar S. Azmi"'
Autor:
Abdelrahim Maen, Betul Gok Yavuz, Yehia I. Mohamed, Abdullah Esmail, Jianming Lu, Amr Mohamed, Asfar S. Azmi, Mohamed Kaseb, Osama Kasseb, Dan Li, Michelle Gocio, Mehmet Kocak, Abdelhafez Selim, Qing Ma, Ahmed O. Kaseb
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Thymoquinone TQ, an active ingredient of Nigella Sativa, has been shown to inhibit COVID-19 symptoms in clinical trials. Thymoquinone Formulation (TQF or NP-101) is developed as a novel enteric-coated medication derivative from Nigella Sativa. TQF co
Externí odkaz:
https://doaj.org/article/1173d8f5ba9d4781bcf404aa0ad63ed4
Autor:
Md. Hafiz Uddin, Mohammad Najeeb Al‐Hallak, Husain Yar Khan, Amro Aboukameel, Yiwei Li, Sahar F. Bannoura, Gregory Dyson, Seongho Kim, Yosef Mzannar, Ibrahim Azar, Tanya Odisho, Amr Mohamed, Yosef Landesman, Steve Kim, Rafic Beydoun, Ramzi M. Mohammad, Philip A. Philip, Anthony F. Shields, Asfar S. Azmi
Publikováno v:
Clinical and Translational Medicine, Vol 13, Iss 12, Pp n/a-n/a (2023)
Abstract Background The majority of pancreatic ductal adenocarcinoma (PDAC) patients experience disease progression while on treatment with gemcitabine and nanoparticle albumin‐bound (nab)‐paclitaxel (GemPac) necessitating the need for a more eff
Externí odkaz:
https://doaj.org/article/746a7f24c49c48c5878e393d3f6d9f55
Autor:
Amr Mohamed, Asfar S. Azmi, Sylvia L. Asa, Sree Harsha Tirumani, Amit Mahipal, Sakti Cjakrabarti, David Bajor, J. Eva Selfridge, Ahmed O. Kaseb
Publikováno v:
Current Oncology, Vol 29, Iss 11, Pp 9018-9030 (2022)
Background: Neuroendocrine neoplasms (NENs) are a heterogeneous group of cancers that had a significant increase in annual incidence in the last decade. They can be divided into well-differentiated neuroendocrine tumors (NETs) and poorly differentiat
Externí odkaz:
https://doaj.org/article/80967a0031ad4e5b89627f3228c23052
Autor:
Jessica Elderkin, Najeeb Al Hallak, Asfar S. Azmi, Hussein Aoun, Jeffrey Critchfield, Miguel Tobon, Eliza W. Beal
Publikováno v:
Cancers, Vol 15, Iss 21, p 5118 (2023)
Hepatocellular carcinoma (HCC) ranks fourth in cancer-related deaths worldwide. Semiannual surveillance of the disease for patients with cirrhosis or hepatitis B virus allows for early detection with more favorable outcomes. The current underuse of s
Externí odkaz:
https://doaj.org/article/eb79cb6cee1c470c9feee75caf18c405
Autor:
Husain Yar Khan, PhD, Mandana Kamgar, MD, Amro Aboukameel, MS, Sahar Bannoura, MS, Brian Y. Chung, PhD, Yiwei Li, MD, Mohammed Najeeb Al Hallak, MD, Philip A. Philip, MD, PhD, Susan Tsai, MD, Sanjeev Luther, MBA, William A. Hall, MD, Asfar S. Azmi, PhD
Publikováno v:
Advances in Radiation Oncology, Vol 8, Iss 1, Pp 101122- (2023)
Purpose: Local tumor progression is a cause of significant morbidity and mortality in patients with pancreatic ductal adenocarcinoma (PDAC) with surgically unresectable disease. Novel and effective approaches to accomplish durable local control are u
Externí odkaz:
https://doaj.org/article/ee77f111869b4d7c8620b432196590f6
Autor:
Vijendra Singh, Mohammed Hafiz Uddin, Jeffrey A. Zonder, Asfar S. Azmi, Suresh Kumar Balasubramanian
Publikováno v:
Molecular Cancer, Vol 20, Iss 1, Pp 1-10 (2021)
Abstract Although mechanistic studies clarifying the molecular underpinnings of AML have facilitated the development of several novel targeted therapeutics, most AML patients still relapse. Thus, overcoming the inherent and acquired resistance to cur
Externí odkaz:
https://doaj.org/article/e69252ad152d4db9abeb3705116de2f9
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
KRAS mutations are among the most commonly occurring mutations in cancer. After being deemed undruggable for decades, KRAS G12C specific inhibitors showed that small molecule inhibitors can be developed against this notorious target. At the same time
Externí odkaz:
https://doaj.org/article/bf8d5909f59d4a7ab5eb5fdc2beb73ec
Autor:
Misako Nagasaka, Mohammed Hafiz Uddin, Mohammed Najeeb Al-Hallak, Sarah Rahman, Suresh Balasubramanian, Ammar Sukari, Asfar S. Azmi
Publikováno v:
Molecular Cancer, Vol 20, Iss 1, Pp 1-16 (2021)
Abstract Liquid biopsy is now considered a valuable diagnostic tool for advanced metastatic non-small cell lung cancer (NSCLC). In NSCLC, circulating tumor DNA (ctDNA) analysis has been shown to increase the chances of identifying the presence of tar
Externí odkaz:
https://doaj.org/article/bae4d04066c14c28aa6aacad179cce99
Publikováno v:
Heliyon, Vol 6, Iss 11, Pp e05442- (2020)
Development of acquired resistance to cisplatin (CDDP) is a major obstacle in the treatment of ovarian cancer patients. According to the cancer stem cell (CSC) hypothesis, the recurrence and chemoresistance are presumed to be linked to cancer stem/pr
Externí odkaz:
https://doaj.org/article/5b248ce1d8e345e1a6e106073dd11a5b
Autor:
Rachel E. Sexton BS, Mohammed Najeeb Al Hallak MD, Md. Hafiz Uddin PhD, Maria Diab MD, Asfar S. Azmi PhD
Publikováno v:
Technology in Cancer Research & Treatment, Vol 19 (2020)
Gastric adenocarcinoma is a highly aggressive disease with poor overall survival. The aggressive nature of this disease is in part due to the high intra and inter tumoral heterogeneity and also due to the late diagnosis at presentation. Once progress
Externí odkaz:
https://doaj.org/article/7084db465f554c94b98de5dd13709236