Silencing of microRNA-106b-5p prevents doxorubicin-mediated cardiotoxicity through modulation of the PR55α/YY1/sST2 signaling axis.

Autor: Lax A; Biomedical Research Institute Virgen de la Arrixaca (IMIB-Arrixaca), University of Murcia, 30120 Murcia, Spain., Soler F; Biomedical Research Institute Virgen de la Arrixaca (IMIB-Arrixaca), University of Murcia, 30120 Murcia, Spain., Fernandez Del Palacio MJ; Veterinary Hospital, University of Murcia 30100 Murcia, Spain., Pascual-Oliver S; Biomedical Research Institute Virgen de la Arrixaca (IMIB-Arrixaca), University of Murcia, 30120 Murcia, Spain., Ballester MR; Biomedical Research Institute Virgen de la Arrixaca (IMIB-Arrixaca), University of Murcia, 30120 Murcia, Spain., Fuster JJ; Centro Nacional de Investigaciones Cardiovasculares (CNIC), 28029 Madrid, Spain., Pascual-Figal D; Centro Nacional de Investigaciones Cardiovasculares (CNIC), 28029 Madrid, Spain.; Cardiology Department, Hospital Virgen de la Arrixaca, IMIB-Arrixaca and University of Murcia, 30120 Murcia, Spain.; Centro de Investigación Biomédica en Red Enfermedades Cardiovasculares (CIBERCV), 28029 Madrid, Spain., Asensio-Lopez MDC; Centro Nacional de Investigaciones Cardiovasculares (CNIC), 28029 Madrid, Spain.

Publikováno v: Molecular therapy. Nucleic acids [Mol Ther Nucleic Acids] 2023 May 03; Vol. 32, pp. 704-720. Date of Electronic Publication: 2023 May 03 (Print Publication: 2023).

Pharmacological inhibition of the mitochondrial NADPH oxidase 4/PKCα/Gal-3 pathway reduces left ventricular fibrosis following myocardial infarction.

Autor: Asensio-Lopez MDC; Biomedical Research Institute Virgen de la Arrixaca (IMIB-Arrixaca), University of Murcia, Murcia, Spain., Lax A; Biomedical Research Institute Virgen de la Arrixaca (IMIB-Arrixaca), University of Murcia, Murcia, Spain. Electronic address: alax@um.es., Fernandez Del Palacio MJ; Veterinary Teaching Hospital, Veterinary Medicine and Surgery Department, University of Murcia, Murcia, Spain., Sassi Y; Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, New York., Hajjar RJ; Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, New York., Pascual-Figal DA; Cardiology Department, Clinic and Universitary Hospital Virgen de la Arrixaca, Murcia, Spain; CIBER in Cardiovascular Diseases (CIBERCV), Madrid, Spain.

Publikováno v: Translational research : the journal of laboratory and clinical medicine [Transl Res] 2018 Sep; Vol. 199, pp. 4-23. Date of Electronic Publication: 2018 Apr 23.

Empagliflozin and colchicine in patients with reduced left ventricular ejection fraction following ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention: a study protocol for a randomized, double-blinded, three-arm parallel-group, controlled trial

Autor: Khiali, Sajad¹ (AUTHOR), Taban-Sadeghi, Mohammadreza² (AUTHOR), Sarbakhsh, Parvin³ (AUTHOR), Khezerlouy-Aghdam, Naser² (AUTHOR), Namdar, Hossein² (AUTHOR), Salehi, Rezvanieh² (AUTHOR), Rezagholizadeh, Afra¹ (AUTHOR), Entezari-Maleki, Taher^1,2 (AUTHOR) tentezari@gmail.com

Publikováno v: Trials. 10/6/2023, Vol. 24 Issue 1, p1-12. 12p. 1 Diagram, 1 Chart.

Role and molecular mechanisms of SGLT2 inhibitors in pathological cardiac remodeling (Review).

Autor: Chen, Bixian^1,2 (AUTHOR), Guo, Jing¹ (AUTHOR) xi88056172@163.com, Ye, Hongmei^1,2 (AUTHOR), Wang, Xinyu^1,2 (AUTHOR), Feng, Yufei³ (AUTHOR) xi88056172@163.com

Publikováno v: Molecular Medicine Reports. May2024, Vol. 29 Issue 5, pN.PAG-N.PAG. 1p.

Empagliflozin impact on experimentally induced acetaminophen toxicity: Imprint of mitochondrial dynamics, biogenesis, and cGAS/STING signal in amending liver insult.

Autor: El-Gohary RM; Department of Medical Biochemistry, Faculty of Medicine, Tanta University, Tanta, Egypt., Abdeen A; Department of Forensic Medicine and Toxicology, Faculty of Veterinary Medicine, Benha University, Toukh, Egypt., Ibrahim HA; Department of Medical Biochemistry, Faculty of Medicine, Tanta University, Tanta, Egypt., Taher ES; Department of Basic Medical and Dental Sciences, Faculty of Dentistry, Zarqa University, Zarqa, Jordan., Ghabrial MM; Department of Anatomy and Embryology, Faculty of Medicine, Tanta University, Tanta, Egypt., Younis RL; Department of Physiology, Faculty of Medicine, Tanta University, Tanta, Egypt., Khattab H; Department of Physiology, Faculty of Medicine, Tanta University, Tanta, Egypt., Seleem MA; Department of Medical Pharmacology, Faculty of Medicine, Tanta University, Tanta, Egypt., Alwutayed KM; Department of Biology, College of Science, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia., Mihaela O; Department of Biology, Faculty of Agriculture, University of Life Sciences 'King Michael I' from Timisoara, Timisoara, Romania., Ioan BD; Department of Biology, Faculty of Agriculture, University of Life Sciences 'King Michael I' from Timisoara, Timisoara, Romania., El-Nablaway M; Department of Basic Medical Sciences, College of Medicine, AlMaarefa University, Riyadh, Saudi Arabia., Aldarmahi AA; Department of Basic Science, College of Science and Health Professions, King Saud bin Abdulaziz University for Health Sciences, Jeddah, Saudi Arabia.; National Guard- Health Affairs, King Abdullah International Medical Research Centre, Jeddah, Saudi Arabia., Ibrahim AM; Department of Administration and Nursing Education, College of Nursing, Prince Sattam bin Abdulaziz University, Al-Kharj, Saudi Arabia.; Department of Family and Community Health Nursing, Faculty of Nursing, Port-Said University, Port Said, Egypt., Al-Serwi RH; Department of Basic Sciences, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia., Ghalwash AA; Department of Medical Biochemistry, Faculty of Medicine, Tanta University, Tanta, Egypt.

Publikováno v: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2024 Jul 31; Vol. 38 (14), pp. e23816.