Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Ascención Torres-Escobar"'
Autor:
Ascención Torres-Escobar, Ashley Wilkins, María D. Juárez-Rodríguez, Magdalena Circu, Brian Latimer, Ana-Maria Dragoi, Stanimir S. Ivanov
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract The accidental human pathogen Legionella pneumophila (Lp) is the etiological agent for a severe atypical pneumonia known as Legionnaires’ disease. In human infections and animal models of disease alveolar macrophages are the primary cellul
Externí odkaz:
https://doaj.org/article/4425f9fbfb6c4b7faf351a32a50236d8
Publikováno v:
Journal of Bacteriology
Ehrlichia chaffeensis causes human monocytic ehrlichiosis by replicating within phagosomes of monocytes/macrophages. A function disruption mutation within the pathogen’s ECH_0660 gene, which encodes a phage head-to-tail connector protein, resulted
Publikováno v:
Molecular Oral Microbiology
Aggregatibacter actinomycetemcomitans QseBC regulates its own expression and is essential for biofilm growth and virulence. However, the signal that activates the QseC sensor has not been identified and the qseBC regulon has not been defined. In this
Publikováno v:
Plasmid. 69:211-222
To elucidate the putative function of a gene, effective tools are required for genetic characterization that facilitate its inactivation, deletion or modification on the bacterial chromosome. In the present study, the nucleotide sequence of the Esche
Publikováno v:
Vaccine. 28:5810-5816
Yersinia pestis PsaA is an adhesin that is synthesized inside macrophages. Here, we evaluated the immune profile of codon-optimized Y. pestis PsaA synthesized in a live recombinant attenuated Salmonella vaccine (RASV) strain chi9558. Oral immunizatio
Publikováno v:
FEMS Microbiology Letters. 302:106-113
Yersinia pestis PsaA is an adhesin important for the establishment of bacterial infection. PsaA synthesis requires the products of the psaEFABC genes. Here, by prediction analysis, we identified a PsaA signal sequence with two signal peptidase (SPase
Autor:
Kenneth L. Roland, Jacqueline D. Fetherston, Wei Sun, Ascención Torres-Escobar, Roy Curtiss, Christine G. Branger, Robert D. Perry
Publikováno v:
Vaccine. 27:5363-5370
The use of live recombinant attenuated Salmonella vaccines (RASV) synthesizing Yersinia proteins is a promising approach for controlling infection by Yersinia species. In this study, we constructed attenuated Salmonella strains which synthesize a tru
Publikováno v:
Microbiology (Reading, England). 160(Pt 12)
The QseBC two-component system plays a pivotal role in regulating virulence and biofilm growth of the oral pathogen Aggregatibacter actinomycetemcomitans. We previously showed that QseBC autoregulates the ygiW–qseBC operon. In this study, we charac
Publikováno v:
FEMS Microbiology Letters.
In this study, we show that integration host factor protein (IHF) is required for replication of pYGK plasmids in Aggregatibacter actinomycetemcomitans. YGK plasmids were not replicated in A. actinomycetemcomitans strains lacking either the α- or β
Publikováno v:
Journal of bacteriology. 196(8)
We previously showed that the Aggregatibacter actinomycetemcomitans lsrACDBFG and lsrRK operons are regulated by LsrR and cyclic AMP receptor protein (CRP) and that proper regulation of the lsr locus is required for optimal biofilm growth by A. actin