Predictors for quality of life improvement after surgery for degenerative cervical myelopathy: a prospective multi-center study

Autor: Hiroyuki Inose, Takashi Hirai, Toshitaka Yoshii, Atsushi Kimura, Katsushi Takeshita, Hirokazu Inoue, Asato Maekawa, Kenji Endo, Takuya Miyamoto, Takeo Furuya, Akira Nakamura, Kanji Mori, Shunsuke Kanbara, Shiro Imagama, Shoji Seki, Shunji Matsunaga, Atsushi Okawa

Publikováno v: Health and Quality of Life Outcomes, Vol 19, Iss 1, Pp 1-8 (2021)

Abstract Background Degenerative cervical myelopathy (DCM) can significantly impair a patient’s quality of life (QOL). In this study, we aimed to identify predictors associated with QOL improvement after surgery for DCM. Methods This study included

Externí odkaz: https://doaj.org/article/f092fbe5f8674f9fbad172ba62f3f3b5

Factors contributing to neck pain in patients with degenerative cervical myelopathy: A prospective multicenter study

Autor: Hiroyuki Inose, Takashi Hirai, Toshitaka Yoshii, Atsushi Kimura, Katsushi Takeshita, Hirokazu Inoue, Asato Maekawa, Kenji Endo, Takuya Miyamoto, Takeo Furuya, Akira Nakamura, Kanji Mori, Shunsuke Kanbara, Shiro Imagama, Shoji Seki, Shunji Matsunaga, Kunihiko Takahashi, Atsushi Okawa

Publikováno v: Journal of Orthopaedic Surgery, Vol 30 (2022)

Purpose Although the understanding of the mechanisms of low back pain due to spinopelvic sagittal imbalance has strengthened, the understanding of the mechanisms of neck pain remains insufficient. Thus, this study aimed to identify the factors associ

Externí odkaz: https://doaj.org/article/6477ad1311004e7f80567c2cb7def69e

Global sagittal spinal alignment at cervical flexion in patients with dropped head syndrome

Autor: Takamitsu Konishi, Kenji Endo, Takato Aihara, Hidekazu Suzuki, Yuji Matsuoka, Hirosuke Nishimura, Taichiro Takamatsu, Kazuma Murata, Takuya Kusakabe, Asato Maekawa, Yasunobu Sawaji, Kengo Yamamoto

Publikováno v: Journal of Orthopaedic Surgery, Vol 28 (2020)

Purpose: Dropped head syndrome (DHS) is characterized by the passively correctable chin-on-chest deformity. The characteristic feature is emphasized in the cervical flexion position. The purpose of this study was to analyze the influence of cervical

Externí odkaz: https://doaj.org/article/3d513cc296d64b938306e03673d56d6e

DUSP-1 Induced by PGE2 and PGE1 Attenuates IL-1β-Activated MAPK Signaling, Leading to Suppression of NGF Expression in Human Intervertebral Disc Cells

Autor: Takuya Kusakabe, Yasunobu Sawaji, Kenji Endo, Hidekazu Suzuki, Takamitsu Konishi, Asato Maekawa, Kazuma Murata, Kengo Yamamoto

Publikováno v: International Journal of Molecular Sciences, Vol 23, Iss 371, p 371 (2022)
International Journal of Molecular Sciences; Volume 23; Issue 1; Pages: 371
International Journal of Molecular Sciences

The molecular mechanism of discogenic low back pain (LBP) involves nonphysiological nerve invasion into a degenerated intervertebral disc (IVD), induced by nerve growth factor (NGF). Selective cyclooxygenase (COX)-2 inhibitors are mainly used in the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7c9a5ccf41d6c8a632ab8a38c2612f2
https://www.mdpi.com/1422-0067/23/1/371

Artificial intelligence for the detection of vertebral fractures on plain spinal radiography

Autor: Kenji Endo, Hideya Yamauchi, Kengo Yamamoto, Takato Aihara, Kei Kanazawa, Hiroo Endo, Hanako Tsuji, Yuji Matsuoka, Taichiro Takamatsu, Asato Maekawa, Shigeru Inoue, Takamitsu Konishi, Hidekazu Suzuki, Hiroyuki Kikuchi, Yasunobu Sawaji, Kazuma Murata, Noritoshi Fukushima, Hiroki Sato, Hirosuke Nishimura

Publikováno v: Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)
Scientific Reports

Vertebral fractures (VFs) cause serious problems, such as substantial functional loss and a high mortality rate, and a delayed diagnosis may further worsen the prognosis. Plain thoracolumbar radiography (PTLR) is an essential method for the evaluatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99641a8e7aaae6d3d7bbdcb4c72e3199
http://link.springer.com/article/10.1038/s41598-020-76866-w